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Search results 701 to 800 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0005199 | structural constituent of cell wall
Description: The action of a molecule that contributes to the structural integrity of a cell wall.
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GO Term
GO:0000808 | origin recognition complex
Description: A multisubunit complex that is located at the replication origins of a chromosome.
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GO Term
GO:0005672 | transcription factor TFIIA complex
Description: A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12).
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GO Term
GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Description: Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.
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GO Term
GO:0031047 | gene silencing by RNA
Description: Any process in which RNA molecules inactivate expression of target genes.
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GO Term
GO:0004807 | triose-phosphate isomerase activity
Description: Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
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GO Term
GO:0006275 | regulation of DNA replication
Description: Any process that modulates the frequency, rate or extent of DNA replication.
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GO Term
GO:0003935 | GTP cyclohydrolase II activity
Description: Catalysis of the reaction: GTP + 3 H(2)O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H(+).
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GO Term
GO:0008686 | 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
Description: Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+).
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GO Term
GO:0009231 | riboflavin biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
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GO Term
GO:0031011 | Ino80 complex
Description: A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity and 3' to 5' DNA helicase activity.
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GO Term
GO:0003849 | 3-deoxy-7-phosphoheptulonate synthase activity
Description: Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate.
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GO Term
GO:0006208 | pyrimidine nucleobase catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
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GO Term
GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Description: Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
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GO Term
GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Description: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.
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GO Term
GO:0000015 | phosphopyruvate hydratase complex
Description: A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
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GO Term
GO:0004634 | phosphopyruvate hydratase activity
Description: Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
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GO Term
GO:0004519 | endonuclease activity
Description: Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
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GO Term
GO:0004375 | glycine dehydrogenase (decarboxylating) activity
Description: Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2.
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GO Term
GO:0004197 | cysteine-type endopeptidase activity
Description: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
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GO Term
GO:0009089 | lysine biosynthetic process via diaminopimelate
Description: The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.
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GO Term
GO:0010285 | L,L-diaminopimelate aminotransferase activity
Description: Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+).
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GO Term
GO:0016485 | protein processing
Description: Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
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GO Term
GO:0009269 | response to desiccation
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.
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GO Term
GO:0016307 | phosphatidylinositol phosphate kinase activity
Description: Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.
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GO Term
GO:0046488 | phosphatidylinositol metabolic process
Description: The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
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GO Term
GO:0009378 | four-way junction helicase activity
Description: Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions.
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GO Term
GO:0004497 | monooxygenase activity
Description: Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
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GO Term
GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor
Description: Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen.
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GO Term
GO:0032040 | small-subunit processome
Description: A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
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GO Term
GO:0006452 | translational frameshifting
Description: A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon.
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GO Term
GO:0043022 | ribosome binding
Description: Interacting selectively and non-covalently with any part of a ribosome.
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GO Term
GO:0045901 | positive regulation of translational elongation
Description: Any process that activates or increases the frequency, rate or extent of translational elongation.
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GO Term
GO:0045905 | positive regulation of translational termination
Description: Any process that activates or increases the frequency, rate or extent of translational termination.
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GO Term
GO:0030145 | manganese ion binding
Description: Interacting selectively and non-covalently with manganese (Mn) ions.
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GO Term
GO:0001510 | RNA methylation
Description: Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
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GO Term
GO:0005838 | proteasome regulatory particle
Description: A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.
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GO Term
GO:0005267 | potassium channel activity
Description: Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
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GO Term
GO:0009011 | starch synthase activity
Description: Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1).
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GO Term
GO:0009250 | glucan biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.
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GO Term
GO:0004070 | aspartate carbamoyltransferase activity
Description: Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate.
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GO Term
GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
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GO Term
GO:0016743 | carboxyl- or carbamoyltransferase activity
Description: Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).
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GO Term
GO:0006790 | sulfur compound metabolic process
Description: The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
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GO Term
GO:0008441 | 3'(2'),5'-bisphosphate nucleotidase activity
Description: Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.
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GO Term
GO:0046854 | phosphatidylinositol phosphorylation
Description: The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.
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GO Term
GO:0009349 | riboflavin synthase complex
Description: An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine.
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GO Term
GO:0016209 | antioxidant activity
Description: Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
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GO Term
GO:0051920 | peroxiredoxin activity
Description: Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
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GO Term
GO:0033180 | proton-transporting V-type ATPase, V1 domain
Description: A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.
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GO Term
GO:0034220 | ion transmembrane transport
Description: A process in which an ion is transported across a membrane.
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GO Term
GO:0004351 | glutamate decarboxylase activity
Description: Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.
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GO Term
GO:0006536 | glutamate metabolic process
Description: The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
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GO Term
GO:0016831 | carboxy-lyase activity
Description: Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.
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GO Term
GO:0019752 | carboxylic acid metabolic process
Description: The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
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GO Term
GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Description: Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.
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GO Term
GO:0003993 | acid phosphatase activity
Description: Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.
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GO Term
GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
Description: Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
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GO Term
GO:0009039 | urease activity
Description: Catalysis of the reaction: urea + H2O = CO2 + 2 NH3.
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GO Term
GO:0016151 | nickel cation binding
Description: Interacting selectively and non-covalently with nickel (Ni) cations.
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GO Term
GO:0019627 | urea metabolic process
Description: The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.
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GO Term
GO:0043419 | urea catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
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GO Term
GO:0016651 | oxidoreductase activity, acting on NAD(P)H
Description: Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
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GO Term
GO:0004573 | mannosyl-oligosaccharide glucosidase activity
Description: Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).
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GO Term
GO:0009311 | oligosaccharide metabolic process
Description: The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
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GO Term
GO:0005094 | Rho GDP-dissociation inhibitor activity
Description: Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.
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GO Term
GO:0004072 | aspartate kinase activity
Description: Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+).
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GO Term
GO:0004412 | homoserine dehydrogenase activity
Description: Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.
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GO Term
GO:0008652 | cellular amino acid biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
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GO Term
GO:0009067 | aspartate family amino acid biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
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GO Term
GO:0004013 | adenosylhomocysteinase activity
Description: Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.
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GO Term
GO:0006730 | one-carbon metabolic process
Description: The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
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GO Term
GO:0004663 | Rab geranylgeranyltransferase activity
Description: Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.
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GO Term
GO:0018344 | protein geranylgeranylation
Description: The covalent attachment of a geranylgeranyl group to a protein.
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GO Term
GO:0005885 | Arp2/3 protein complex
Description: A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
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GO Term
GO:0030041 | actin filament polymerization
Description: Assembly of actin filaments by the addition of actin monomers to a filament.
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GO Term
GO:0034314 | Arp2/3 complex-mediated actin nucleation
Description: The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
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GO Term
GO:0004045 | aminoacyl-tRNA hydrolase activity
Description: Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
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GO Term
GO:0010277 | chlorophyllide a oxygenase [overall] activity
Description: Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.
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GO Term
GO:0019904 | protein domain specific binding
Description: Interacting selectively and non-covalently with a specific domain of a protein.
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GO Term
GO:0004112 | cyclic-nucleotide phosphodiesterase activity
Description: Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.
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GO Term
GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity
Description: Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
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GO Term
GO:0018279 | protein N-linked glycosylation via asparagine
Description: The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.
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GO Term
GO:0003825 | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
Description: Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.
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GO Term
GO:0004523 | RNA-DNA hybrid ribonuclease activity
Description: Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.
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GO Term
GO:0005093 | Rab GDP-dissociation inhibitor activity
Description: Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding.
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GO Term
GO:0004721 | phosphoprotein phosphatase activity
Description: Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
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GO Term
GO:0000775 | chromosome, centromeric region
Description: The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
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GO Term
GO:0004491 | methylmalonate-semialdehyde dehydrogenase (acylating) activity
Description: Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+.
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GO Term
GO:0008883 | glutamyl-tRNA reductase activity
Description: Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.
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GO Term
GO:0006813 | potassium ion transport
Description: The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0004506 | squalene monooxygenase activity
Description: Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+).
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GO Term
GO:0019295 | coenzyme M biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
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GO Term
GO:0010333 | terpene synthase activity
Description: Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.
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GO Term
GO:0008531 | riboflavin kinase activity
Description: Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+).
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GO Term
GO:0031145 | anaphase-promoting complex-dependent catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
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GO Term
GO:0006308 | DNA catabolic process
Description: The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
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GO Term
GO:0008352 | katanin complex
Description: A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).
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GO Term
GO:0051013 | microtubule severing
Description: The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends
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GO Term
GO:0004097 | catechol oxidase activity
Description: Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O.
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