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Search results 1901 to 2000 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0051011 | microtubule minus-end binding
Description: Interacting selectively and non-covalently with the minus end of a microtubule.
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GO Term
GO:0032264 | IMP salvage
Description: Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.
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GO Term
GO:0005784 | Sec61 translocon complex
Description: A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events.
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GO Term
GO:0007059 | chromosome segregation
Description: The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
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GO Term
GO:0022625 | cytosolic large ribosomal subunit
Description: The large subunit of a ribosome located in the cytosol.
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GO Term
GO:0003680 | AT DNA binding
Description: Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).
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GO Term
GO:0071816 | tail-anchored membrane protein insertion into ER membrane
Description: A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.
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GO Term
GO:0005092 | GDP-dissociation inhibitor activity
Description: Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.
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GO Term
GO:0005968 | Rab-protein geranylgeranyltransferase complex
Description: An protein-containing complex which catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein. In mammals it is composed of an alpha and a beta subunit, and associates with an accessory protein Rep (Rab escort protein).
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GO Term
GO:0030906 | retromer, cargo-selective complex
Description: The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
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GO Term
GO:0071949 | FAD binding
Description: Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
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GO Term
GO:0030619 | U1 snRNA binding
Description: Interacting selectively and non-covalently with the U1 small nuclear RNA (U1 snRNA).
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GO Term
GO:0003955 | NAD(P)H dehydrogenase (quinone) activity
Description: Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.
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GO Term
GO:0070006 | metalloaminopeptidase activity
Description: Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
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GO Term
GO:0032051 | clathrin light chain binding
Description: Interacting selectively and non-covalently with a clathrin light chain.
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GO Term
GO:0071439 | clathrin complex
Description: A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.
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GO Term
GO:0010242 | oxygen evolving activity
Description: Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.
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GO Term
GO:0045492 | xylan biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
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GO Term
GO:0015098 | molybdate ion transmembrane transporter activity
Description: Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid.
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GO Term
GO:0015689 | molybdate ion transport
Description: The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid.
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GO Term
GO:0044571 | [2Fe-2S] cluster assembly
Description: The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.
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GO Term
GO:0071704 | organic substance metabolic process
Description: The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
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GO Term
GO:0098599 | palmitoyl hydrolase activity
Description: Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.
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GO Term
GO:0030008 | TRAPP complex
Description: A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.
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GO Term
GO:1990380 | Lys48-specific deubiquitinase activity
Description: Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein.
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GO Term
GO:0005049 | nuclear export signal receptor activity
Description: Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.
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GO Term
GO:0008942 | nitrite reductase [NAD(P)H] activity
Description: Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+.
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GO Term
GO:0008252 | nucleotidase activity
Description: Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate.
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GO Term
GO:0043015 | gamma-tubulin binding
Description: Interacting selectively and non-covalently with the microtubule constituent protein gamma-tubulin.
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GO Term
GO:0033617 | mitochondrial respiratory chain complex IV assembly
Description: The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
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GO Term
GO:1990904 | ribonucleoprotein complex
Description: A macromolecular complex containing both protein and RNA molecules.
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GO Term
GO:0120009 | intermembrane lipid transfer
Description: The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).
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GO Term
GO:0120013 | lipid transfer activity
Description: Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
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GO Term
GO:0030014 | CCR4-NOT complex
Description: The evolutionarily conserved CCR4-NOT complex is involved in several aspects of mRNA metabolism, including repression and activation of mRNA initiation, control of mRNA elongation, and the deadenylation and subsequent degradation of mRNA. In Saccharomyces the CCR4-NOT complex comprises a core complex of 9 proteins (Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p), Caf4p, Caf16p, and several less well characterized proteins.
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GO Term
GO:0009785 | blue light signaling pathway
Description: The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.
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GO Term
GO:0009882 | blue light photoreceptor activity
Description: The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.
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GO Term
GO:0010112 | regulation of systemic acquired resistance
Description: Any process that modulates the frequency, rate or extent of systemic acquired resistance.
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GO Term
GO:0034061 | DNA polymerase activity
Description: Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.
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GO Term
GO:0030286 | dynein complex
Description: Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
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GO Term
GO:0030015 | CCR4-NOT core complex
Description: The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.
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GO Term
GO:0000956 | nuclear-transcribed mRNA catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
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GO Term
GO:0046910 | pectinesterase inhibitor activity
Description: Stops, prevents or reduces the activity of any pectinesterase enzyme.
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GO Term
GO:0031307 | integral component of mitochondrial outer membrane
Description: The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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GO Term
GO:0006996 | organelle organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
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GO Term
GO:0010011 | auxin binding
Description: Interacting selectively and non-covalently with auxin, plant hormones that regulate aspects of plant growth.
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GO Term
GO:0009742 | brassinosteroid mediated signaling pathway
Description: A series of molecular signals mediated by the detection of brassinosteroid.
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GO Term
GO:0019888 | protein phosphatase regulator activity
Description: Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
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GO Term
GO:0016279 | protein-lysine N-methyltransferase activity
Description: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
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GO Term
GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific
Description: A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
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GO Term
GO:0000987 | proximal promoter sequence-specific DNA binding
Description: Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter. The proximal promoter is in cis with and relatively close to the core promoter.
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GO Term
GO:0046608 | carotenoid isomerase activity
Description: Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids.
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GO Term
GO:0005096 | GTPase activator activity
Description: Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
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GO Term
GO:0003975 | UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
Description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.
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GO Term
GO:0031119 | tRNA pseudouridine synthesis
Description: The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
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GO Term
GO:0006401 | RNA catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
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GO Term
GO:0032299 | ribonuclease H2 complex
Description: A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.
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GO Term
GO:0019264 | glycine biosynthetic process from serine
Description: The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine.
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GO Term
GO:0035999 | tetrahydrofolate interconversion
Description: The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
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GO Term
GO:1990316 | Atg1/ULK1 kinase complex
Description: A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.
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GO Term
GO:0006696 | ergosterol biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
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GO Term
GO:0051996 | squalene synthase activity
Description: Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate.
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GO Term
GO:0003983 | UTP:glucose-1-phosphate uridylyltransferase activity
Description: Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
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GO Term
GO:0006011 | UDP-glucose metabolic process
Description: The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
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GO Term
GO:0070569 | uridylyltransferase activity
Description: Catalysis of the transfer of an uridylyl group to an acceptor.
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GO Term
GO:0019441 | tryptophan catabolic process to kynurenine
Description: The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.
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GO Term
GO:0061630 | ubiquitin protein ligase activity
Description: Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
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GO Term
GO:0090730 | Las1 complex
Description: A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).
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GO Term
GO:0000737 | DNA catabolic process, endonucleolytic
Description: The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.
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GO Term
GO:0016889 | endodeoxyribonuclease activity, producing 3'-phosphomonoesters
Description: Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
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GO Term
GO:0051743 | red chlorophyll catabolite reductase activity
Description: Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence.
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GO Term
GO:0005262 | calcium channel activity
Description: Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
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GO Term
GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity
Description: Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
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GO Term
GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport
Description: The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
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GO Term
GO:0000469 | cleavage involved in rRNA processing
Description: Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
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GO Term
GO:0046537 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Description: Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate.
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GO Term
GO:0030880 | RNA polymerase complex
Description: Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits.
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GO Term
GO:0032981 | mitochondrial respiratory chain complex I assembly
Description: The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
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GO Term
GO:0004127 | cytidylate kinase activity
Description: Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.
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GO Term
GO:0003860 | 3-hydroxyisobutyryl-CoA hydrolase activity
Description: Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.
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GO Term
GO:0005854 | nascent polypeptide-associated complex
Description: A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.
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GO Term
GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter
Description: Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
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GO Term
GO:0032366 | intracellular sterol transport
Description: The directed movement of sterols within cells.
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GO Term
GO:0009793 | embryo development ending in seed dormancy
Description: The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
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GO Term
GO:0089701 | U2AF
Description: A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point.
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GO Term
GO:0097428 | protein maturation by iron-sulfur cluster transfer
Description: The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
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GO Term
GO:0009263 | deoxyribonucleotide biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
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GO Term
GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA
Description: Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
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GO Term
GO:0008047 | enzyme activator activity
Description: Binds to and increases the activity of an enzyme.
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GO Term
GO:0000030 | mannosyltransferase activity
Description: Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
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GO Term
GO:0030975 | thiamine binding
Description: Interacting selectively and non-covalently with thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
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GO Term
GO:0016920 | pyroglutamyl-peptidase activity
Description: Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.
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GO Term
GO:0061608 | nuclear import signal receptor activity
Description: Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
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GO Term
GO:1990879 | CST complex
Description: A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.
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GO Term
GO:0051016 | barbed-end actin filament capping
Description: The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
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GO Term
GO:0047918 | GDP-mannose 3,5-epimerase activity
Description: Catalysis of the reaction: GDP-mannose = GDP-L-galactose.
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GO Term
GO:0009723 | response to ethylene
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
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GO Term
GO:0038199 | ethylene receptor activity
Description: Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.
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GO Term
GO:0051740 | ethylene binding
Description: Interacting selectively and non-covalently with ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
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GO Term
GO:0009411 | response to UV
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
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GO Term
GO:0008553 | proton-exporting ATPase activity, phosphorylative mechanism
Description: Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
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