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Search results 4801 to 4900 out of 202262 for *

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Categories

Category: OntologyTerm
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Type Details Score
Ontology Term
PANTHER:PTHR12277 | ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN
 
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Ontology Term
PANTHER:PTHR10173 | METHIONINE SULFOXIDE REDUCTASE
 
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Ontology Term
PANTHER:PTHR10173:SF6 | MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE
 
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Ontology Term
Pfam:PF01625 | Peptide methionine sulfoxide reductase
Description: This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine.
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Ontology Term
Pfam:PF07910 | Peptidase family C78
Description: This family formerly known as DUF1671 has been shown to be a cysteine peptidase called (Ufm1)-specific protease [1].
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Ontology Term
PANTHER:PTHR22748 | AP ENDONUCLEASE
 
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Ontology Term
Pfam:PF02364 | 1,3-beta-glucan synthase component
Description: This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyses the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall [1]. The reaction catalysed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1).
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Ontology Term
Pfam:PF14288 | 1,3-beta-glucan synthase subunit FKS1, domain-1
Description: The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself [1]. This family is found on proteins with family Glucan_synthase, Pfam:PF02364.
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Ontology Term
PANTHER:PTHR11119:SF9 | ADENINE/GUANINE PERMEASE AZG1
 
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Ontology Term
Pfam:PF13422 | Domain of unknown function (DUF4110)
Description: This is a family that is found predominantly at the C-terminus of Kelch-containing proteins. However, the exact function of this region is not known.
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Ontology Term
PANTHER:PTHR13932 | COPROPORPHYRINIGEN III OXIDASE
 
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Ontology Term
PANTHER:PTHR11135 | HISTONE ACETYLTRANSFERASE-RELATED
 
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Ontology Term
PANTHER:PTHR15830 | TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER
 
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Ontology Term
Pfam:PF10193 | Telomere length regulation protein
Description: This family is the central conserved 110 amino acid region of a group of proteins called telomere-length regulation or clock abnormal protein-2 which are conserved from plants to humans. The full-length protein regulates telomere length and contributes to silencing of sub-telomeric regions. In vitro the protein binds to telomeric DNA repeats.
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Ontology Term
PANTHER:PTHR24089:SF150 | MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN
 
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Ontology Term
Pfam:PF05191 | Adenylate kinase, active site lid
Description: Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organisms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function [1].
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Ontology Term
PANTHER:PTHR11599:SF3 | PROTEASOME SUBUNIT BETA TYPE
 
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Ontology Term
PANTHER:PTHR13403 | SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1
 
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Ontology Term
PANTHER:PTHR13403:SF6 | SNURPORTIN-1
 
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Ontology Term
PANTHER:PTHR31198 | COILED-COIL DOMAIN-CONTAINING PROTEIN 84
 
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Ontology Term
PANTHER:PTHR31198:SF1 | CENTROSOMAL AT-AC SPLICING FACTOR
 
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Ontology Term
Pfam:PF14968 | Coiled coil protein 84
Description: The function of this coiled-coil domain-containing family is not known. It is found in eukaryotes.
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Ontology Term
PANTHER:PTHR18968:SF13 | ACETOLACTATE SYNTHASE, CHLOROPLASTIC
 
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Ontology Term
Pfam:PF00205 | Thiamine pyrophosphate enzyme, central domain
Description: The central domain of TPP enzymes contains a 2-fold Rossman fold.
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Ontology Term
Pfam:PF02775 | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
Description: NULL
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Ontology Term
PANTHER:PTHR13468 | DEK PROTEIN
 
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Ontology Term
PANTHER:PTHR24015:SF72 | OS04G0436800 PROTEIN
 
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Ontology Term
PANTHER:PTHR12802:SF2 | SWI/SNF COMPLEX SUBUNIT SWI3A
 
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Ontology Term
PANTHER:PTHR21535 | MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8
 
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Ontology Term
PANTHER:PTHR24067:SF29 | UBIQUITIN-CONJUGATING ENZYME E2 K
 
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Ontology Term
PANTHER:PTHR13199 | GH03947P
 
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Ontology Term
Pfam:PF13889 | Chromosome segregation during meiosis
Description: The proteins come from eukaryotes, plants and animals, and are necessary for chromosome segregation during meiosis.
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Ontology Term
Pfam:PF13915 | Domain of unknown function (DUF4210)
Description: This short domain is found in fungi, plants and animals, and the proteins appear to be necessary for chromosome segregation during meiosis.
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Ontology Term
PANTHER:PTHR10627 | SCP160
 
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Ontology Term
PANTHER:PTHR11638:SF19 | CASEINOLYTIC PEPTIDASE B PROTEIN HOMOLOG
 
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Ontology Term
PANTHER:PTHR10335 | RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN
 
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Ontology Term
Pfam:PF01269 | Fibrillarin
Description: NULL
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Ontology Term
PANTHER:PTHR22980 | CORTISTATIN
 
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Ontology Term
PANTHER:PTHR22980:SF0 | CENTROMERE PROTEIN S
 
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Ontology Term
Pfam:PF15630 | CENP-S protein
Description: CENP-S is a family of vertebral and fungal kinetochore component proteins. CENP-S complexes with CENP-X to form a stable CENP-T-W-S-X heterotetramer.
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Ontology Term
Pfam:PF06206 | CpeT/CpcT family (DUF1001)
Description: This family consists of proteins of proteins belonging to the CpeT/CpcT family. These proteins are around 200 amino acids in length. The proteins contain a conserved motif PYR in the amino terminal half of the protein that may be functionally important. The species distribution of the family is interesting. So far it is restricted to cyanobacteria, cryptomonads and plants. It has been shown that CpcT encodes a bilin lyase responsible for attachment of phycocyanobilin to the beta subunit of phycocyanin [1].
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Ontology Term
PANTHER:PTHR11073 | CALRETICULIN AND CALNEXIN
 
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Ontology Term
PANTHER:PTHR11073:SF1 | CALNEXIN 14D-RELATED
 
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Ontology Term
Pfam:PF00262 | Calreticulin family
Description: NULL
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Ontology Term
PANTHER:PTHR12302 | EBNA2 BINDING PROTEIN P100
 
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Ontology Term
PANTHER:PTHR12302:SF0 | SERINE/THREONINE-PROTEIN KINASE 31
 
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Ontology Term
Pfam:PF00565 | Staphylococcal nuclease homologue
Description: Present in all three domains of cellular life. Four copies in the transcriptional coactivator p100: these, however, appear to lack the active site residues of Staphylococcal nuclease. Positions 14 (Asp-21), 34 (Arg-35), 39 (Asp-40), 42 (Glu-43) and 110 (Arg-87) [SNase numbering in parentheses] are thought to be involved in substrate-binding and catalysis.
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Ontology Term
Pfam:PF00567 | Tudor domain
Description: NULL
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Ontology Term
PANTHER:PTHR24015:SF148 | SUBFAMILY NOT NAMED
 
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Ontology Term
PANTHER:PTHR21347 | CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED
 
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Ontology Term
Pfam:PF05602 | Cleft lip and palate transmembrane protein 1 (CLPTM1)
Description: This family consists of several eukaryotic cleft lip and palate transmembrane protein 1 sequences. Cleft lip with or without cleft palate is a common birth defect that is genetically complex. The nonsyndromic forms have been studied genetically using linkage and candidate-gene association studies with only partial success in defining the loci responsible for orofacial clefting. CLPTM1 encodes a transmembrane protein and has strong homology to two Caenorhabditis elegans genes, suggesting that CLPTM1 may belong to a new gene family [1]. This family also contains the human cisplatin resistance related protein CRR9p which is associated with CDDP-induced apoptosis [2].
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Ontology Term
PANTHER:PTHR21660 | THIOESTERASE SUPERFAMILY MEMBER-RELATED
 
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Ontology Term
PANTHER:PTHR16193 | UNCHARACTERIZED
 
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Ontology Term
PANTHER:PTHR16193:SF0 | TETRATRICOPEPTIDE REPEAT PROTEIN 27
 
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Ontology Term
PANTHER:PTHR24093:SF82 | CATION-TRANSPORTING ATPASE 13A1-RELATED
 
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Ontology Term
PANTHER:PTHR15546 | BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN, 2A
 
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Ontology Term
Pfam:PF10537 | ATP-utilising chromatin assembly and remodelling N-terminal
Description: ACF (for ATP-utilising chromatin assembly and remodelling factor) is a chromatin-remodelling complex that catalyses the ATP-dependent assembly of periodic nucleosome arrays. The WAC (WSTF/Acf1/cbp146) domain is an approximately 110-residue module present at the N-termini of Acf1-related proteins in a variety of organisms. The DNA-binding region of Acf1 includes the WAC domain, which is necessary for the efficient binding of ACF complex to DNA.
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Ontology Term
PANTHER:PTHR22870:SF26 | UVB-RESISTANCE PROTEIN UVR8-RELATED
 
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Ontology Term
PANTHER:PTHR12403 | TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2
 
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Ontology Term
Pfam:PF04628 | Sedlin, N-terminal conserved region
Description: Mutations in this protein are associated with the X-linked spondyloepiphyseal dysplasia tarda syndrome (OMIM:313400) [1]. This family represents an N-terminal conserved region.
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Ontology Term
PANTHER:PTHR12403:SF1 | TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2
 
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Ontology Term
PANTHER:PTHR11895:SF7 | GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL
 
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Ontology Term
PANTHER:PTHR11193 | SMALL NUCLEAR RIBONUCLEOPROTEIN E
 
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Ontology Term
PANTHER:PTHR11085 | CHROMATIN REGULATORY PROTEIN SIR2
 
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Ontology Term
Pfam:PF02146 | Sir2 family
Description: This region is characteristic of Silent information regulator 2 (Sir2) proteins, or sirtuins. These are protein deacetylases that depend on nicotine adenine dinucleotide (NAD). They are found in many subcellular locations, including the nucleus, cytoplasm and mitochondria. Eukaryotic forms play in important role in the regulation of transcriptional repression. Moreover, they are involved in microtubule organisation and DNA damage repair processes [1].i
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Ontology Term
PANTHER:PTHR15944 | FARNESYLCYSTEINE LYASE
 
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Ontology Term
PANTHER:PTHR15944:SF0 | PRENYLCYS_LYASE DOMAIN-CONTAINING PROTEIN
 
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Ontology Term
Pfam:PF07156 | Prenylcysteine lyase
Description: This family contains prenylcysteine lyases (EC:1.8.3.5) that are approximately 500 residues long. Prenylcysteine lyase is a FAD-dependent thioether oxidase that degrades a variety of prenylcysteines, producing free cysteine, an isoprenoid aldehyde and hydrogen peroxide as products of the reaction [1]. It has been noted that this enzyme has considerable homology with ClP55, a 55 kDa protein that is associated with chloride ion pumps [2].
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Ontology Term
PANTHER:PTHR31370 | F-BOX PROTEIN FAMILY-LIKE
 
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Ontology Term
PANTHER:PTHR11390 | PROKARYOTIC DNA TOPOISOMERASE
 
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Ontology Term
Pfam:PF01131 | DNA topoisomerase
Description: This subfamily of topoisomerase is divided on the basis that these enzymes preferentially relax negatively supercoiled DNA, from a 5' phospho- tyrosine linkage in the enzyme-DNA covalent intermediate and has high affinity for single stranded DNA.
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Ontology Term
PANTHER:PTHR10322:SF11 | DNA POLYMERASE DELTA CATALYTIC SUBUNIT
 
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Ontology Term
PANTHER:PTHR11516 | PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR
 
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Ontology Term
PANTHER:PTHR11516:SF1 | 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL
 
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Ontology Term
Pfam:PF00676 | Dehydrogenase E1 component
Description: This family uses thiamine pyrophosphate as a cofactor. This family includes pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase and 2-oxoisovalerate dehydrogenase.
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Ontology Term
PANTHER:PTHR16318 | GAMMA-SECRETASE SUBUNIT PEN-2
 
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Ontology Term
PANTHER:PTHR16318:SF0 | GAMMA-SECRETASE SUBUNIT PEN-2
 
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Ontology Term
Pfam:PF10251 | Presenilin enhancer-2 subunit of gamma secretase
Description: This entry is a short 101 peptide protein which is the smallest subunit of the gamma-secretase aspartyl protease complex that catalyses the intramembrane cleavage of a subset of type I transmembrane proteins. The other active constituents of the complex are presenilin (PS) nicastrin and anterior pharynx defective-1 (APH-1) protein. PEN-2 adopts a hairpin orientation in the membrane with its N- and C-terminal domains facing the luminal/extracellular space, and the C-terminal domain maintains PS stability within the complex [1].
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Ontology Term
Pfam:PF11910 | Cyanobacterial and plant NDH-1 subunit O
Description: The proton-pumping NADH:ubiquinone oxidoreductase catalyzes the electron transfer from NADH to ubiquinone linked with proton translocation across the membrane. It is the largest, most complex and least understood of the respiratory chain enzymes and is referred to as Complex I. The subunit composition of the enzyme varies between groups of organisms. Complex I originating from mammalian mitochondria contains 45 different proteins, whereas in bacteria, the corresponding complex NDH-1 consists of 14 different polypeptides. Homologues of these 14 proteins are found among subunits of the mitochondrial complex I, and therefore bacterial NDH-1 might be considered a model proton-pumping NADH dehydrogenase with a minimal set of subunits. Escherichia coli NDH-1 readily disintegrates into 3 subcomplexes: a water-soluble NADH dehydrogenase fragment (NuoE, -F, and -G),the connecting fragment (NuoB, -C, -D, and -I), and the membrane fragment (NuoA, -H, -J, -K, -L, -M, -N). In cyanobacteria and their descendants, the chloroplasts of green plants, the subunit composition of NDH-1 remains obscure. The genes for eleven subunits NdhA-NdhK, homologous to the NuoA-NuoD and NuoH-NuoN of the E. coli complex, have been found in the genome of Synechocystis sp. PCC 6803 which has a family of 6 ndhD genes and a family of 3 ndhF genes. Two reported multisubunit complexes, NDH-1L and NDH-1M, represent distinct NDH-1 complexes in the thylakoid membrane of Synechocystis 6803 -cyanobacterium. NDH-1L was shown to be essential for photoheterotrophic cell growth, whereas expression of NDH-1M was a prerequisite for CO2 uptake and played an important role in growth of cells at low CO2. Here we report the subunit composition of these two complexes. Fifteen proteins were discovered in NDH-1L including NdhL, a new component of the membrane fragment, and Ssl1690 (designated as NdhO), a novel peripheral subunit [1, 2]. The three nuclear-encoded subunits NdhM,NdhN and NdhO are vital for the functional integrity of the plastidial complex [3].
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Ontology Term
Pfam:PF04652 | Vta1 like
Description: Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region [1].
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Ontology Term
PANTHER:PTHR15242 | SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN
 
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Ontology Term
PANTHER:PTHR15242:SF0 | ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 27-RELATED
 
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Ontology Term
PANTHER:PTHR14413 | RIBOSOMAL PROTEIN L17
 
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Ontology Term
Pfam:PF01196 | Ribosomal protein L17
Description: NULL
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Ontology Term
Pfam:PF05479 | Photosystem I reaction centre subunit N (PSAN or PSI-N)
Description: This family contains several Photosystem I reaction centre subunit N (PSI-N) proteins. The protein has no known function although it is localised in the thylakoid lumen [1]. PSI-N is a small extrinsic subunit at the lumen side and is very likely involved in the docking of plastocyanin [2].
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Ontology Term
Pfam:PF00988 | Carbamoyl-phosphate synthase small chain, CPSase domain
Description: The carbamoyl-phosphate synthase domain is in the amino terminus of protein. Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate. This important enzyme initiates both the urea cycle and the biosynthesis of arginine and/or pyrimidines [1]. The carbamoyl-phosphate synthase (CPS) enzyme in prokaryotes is a heterodimer of a small and large chain. The small chain promotes the hydrolysis of glutamine to ammonia, which is used by the large chain to synthesise carbamoyl phosphate. See Pfam:PF00289. The small chain has a GATase domain in the carboxyl terminus. See Pfam:PF00117.
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Ontology Term
Pfam:PF14418 | OST-HTH Associated domain
Description: OHA occurs with OST-HTH [1].
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Ontology Term
Pfam:PF08787 | Alginate lyase
Description: Alginate lyases are enzymes that degrade the linear polysaccharide alignate. They cleave the glycosidic linkage of alignate through a beta-elimination reaction. This family forms an all beta fold and is different to all alpha fold of Pfam:PF05426.
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Ontology Term
PANTHER:PTHR13516:SF0 | PROTEIN ZK632.14
 
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Ontology Term
Pfam:PF15519 | linker between RRM2 and RRM3 domains in RBM39 protein
Description: A conserved linker between the second and the third RRM domain in human RBM39 (CAPER) protein, also present in other RNA binding proteins, especially those involved in RNA splicing. This linker was implicated in interactions with ESR1 and ESR2. Preliminary results from JCSG suggest that this is a structured domain with a well defined fold.
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Ontology Term
PANTHER:PTHR31876 | COV-LIKE PROTEIN 1
 
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Ontology Term
Pfam:PF04367 | Protein of unknown function (DUF502)
Description: Predicted to be an integral membrane protein.
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Ontology Term
PANTHER:PTHR11573 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN
 
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Ontology Term
PANTHER:PTHR11573:SF6 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT
 
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Ontology Term
Pfam:PF00317 | Ribonucleotide reductase, all-alpha domain
Description: NULL
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Ontology Term
Pfam:PF02867 | Ribonucleotide reductase, barrel domain
Description: NULL
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Ontology Term
Pfam:PF03477 | ATP cone domain
Description: NULL
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Ontology Term
PANTHER:PTHR10855 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4
 
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Ontology Term
PANTHER:PTHR10855:SF1 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12
 
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Ontology Term
Pfam:PF14559 | Tetratricopeptide repeat
Description: NULL
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