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Search results 42401 to 42500 out of 44733 for *

Category restricted to GOTerm (x)

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Category: GOTerm
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Type Details Score
GO Term
GO:0007173 | epidermal growth factor receptor signaling pathway
Description: A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
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GO Term
GO:0000285 | 1-phosphatidylinositol-3-phosphate 5-kinase activity
Description: Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+).
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GO Term
GO:0043024 | ribosomal small subunit binding
Description: Interacting selectively and non-covalently with any part of the small ribosomal subunit.
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GO Term
GO:0001520 | outer dense fiber
Description: A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins.
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GO Term
GO:0060828 | regulation of canonical Wnt signaling pathway
Description: Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
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GO Term
GO:0098640 | integrin binding involved in cell-matrix adhesion
Description: Any integrin binding that occurs as part of the process of cell-matrix adhesion.
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GO Term
GO:2000403 | positive regulation of lymphocyte migration
Description: Any process that activates or increases the frequency, rate or extent of lymphocyte migration.
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GO Term
GO:0000829 | inositol heptakisphosphate kinase activity
Description: Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
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GO Term
GO:0097320 | plasma membrane tubulation
Description: A membrane tubulation process occurring in a plasma membrane.
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GO Term
GO:0048666 | neuron development
Description: The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
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GO Term
GO:0046622 | positive regulation of organ growth
Description: Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
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GO Term
GO:0042144 | vacuole fusion, non-autophagic
Description: The fusion of two vacuole membranes to form a single vacuole.
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GO Term
GO:0000329 | fungal-type vacuole membrane
Description: The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
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GO Term
GO:0010099 | regulation of photomorphogenesis
Description: Any process that modulates the rate or extent of photomorphogenesis.
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GO Term
GO:0033612 | receptor serine/threonine kinase binding
Description: Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity.
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GO Term
GO:0010087 | phloem or xylem histogenesis
Description: The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.
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GO Term
GO:0010089 | xylem development
Description: The formation of the principal water-conducting tissue of a vascular plant.
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GO Term
GO:0045746 | negative regulation of Notch signaling pathway
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
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GO Term
GO:0009644 | response to high light intensity
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
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GO Term
GO:0036033 | mediator complex binding
Description: Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
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GO Term
GO:0010183 | pollen tube guidance
Description: The process in which the growth of pollen tube is directed towards the female gametophyte.
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GO Term
GO:0071467 | cellular response to pH
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
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GO Term
GO:0050570 | 4-hydroxythreonine-4-phosphate dehydrogenase activity
Description: Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+.
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GO Term
GO:0030196 | cyanide hydratase activity
Description: Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide.
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GO Term
GO:0019500 | cyanide catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.
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GO Term
GO:0070197 | meiotic attachment of telomere to nuclear envelope
Description: The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.
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GO Term
GO:1990862 | nuclear membrane complex Bqt3-Bqt4
Description: A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4.
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GO Term
GO:1904970 | brush border assembly
Description: The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border.
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GO Term
GO:0050957 | equilibrioception
Description: The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.
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GO Term
GO:0005246 | calcium channel regulator activity
Description: Modulates the activity of a calcium channel.
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GO Term
GO:0032237 | activation of store-operated calcium channel activity
Description: A process that initiates the activity of an inactive store-operated calcium channel.
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GO Term
GO:0031080 | nuclear pore outer ring
Description: A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates).
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GO Term
GO:0043488 | regulation of mRNA stability
Description: Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
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GO Term
GO:0000812 | Swr1 complex
Description: A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.
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GO Term
GO:0070096 | mitochondrial outer membrane translocase complex assembly
Description: The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.
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GO Term
GO:0061671 | Cbp3p-Cbp6 complex
Description: A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly.
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GO Term
GO:0044325 | ion channel binding
Description: Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
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GO Term
GO:1901386 | negative regulation of voltage-gated calcium channel activity
Description: Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.
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GO Term
GO:0031295 | T cell costimulation
Description: The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
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GO Term
GO:0070507 | regulation of microtubule cytoskeleton organization
Description: Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
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GO Term
GO:0000056 | ribosomal small subunit export from nucleus
Description: The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.
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GO Term
GO:0035004 | phosphatidylinositol 3-kinase activity
Description: Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.
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GO Term
GO:0004677 | DNA-dependent protein kinase activity
Description: Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of DNA.
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GO Term
GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity
Description: Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+).
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GO Term
GO:0050254 | rhodopsin kinase activity
Description: Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin.
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GO Term
GO:0022400 | regulation of rhodopsin mediated signaling pathway
Description: Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
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GO Term
GO:0048564 | photosystem I assembly
Description: The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane.
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GO Term
GO:0061098 | positive regulation of protein tyrosine kinase activity
Description: Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
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GO Term
GO:0009639 | response to red or far red light
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
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GO Term
GO:0008353 | RNA polymerase II CTD heptapeptide repeat kinase activity
Description: Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.
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GO Term
GO:0046580 | negative regulation of Ras protein signal transduction
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
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GO Term
GO:0071277 | cellular response to calcium ion
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
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GO Term
GO:0046695 | SLIK (SAGA-like) complex
Description: A SAGA-type histone acetyltransferase complex that contains Rtg2 and a smaller form of Spt7 than the fungal SAGA complex, and lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction.
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GO Term
GO:0052745 | inositol phosphate phosphatase activity
Description: Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate.
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GO Term
GO:0035542 | regulation of SNARE complex assembly
Description: Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
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GO Term
GO:1902936 | phosphatidylinositol bisphosphate binding
Description: Interacting selectively and non-covalently with phosphatidylinositol bisphosphate.
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GO Term
GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding
Description: Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
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GO Term
GO:0044666 | MLL3/4 complex
Description: A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species.
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GO Term
GO:0002080 | acrosomal membrane
Description: The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.
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GO Term
GO:0001965 | G-protein alpha-subunit binding
Description: Interacting selectively and non-covalently with a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.
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GO Term
GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding
Description: Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.
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GO Term
GO:0005178 | integrin binding
Description: Interacting selectively and non-covalently with an integrin.
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GO Term
GO:0071339 | MLL1 complex
Description: A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.
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GO Term
GO:0070513 | death domain binding
Description: Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.
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GO Term
GO:0005042 | netrin receptor activity
Description: Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
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GO Term
GO:0038007 | netrin-activated signaling pathway
Description: A series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.
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GO Term
GO:0002020 | protease binding
Description: Interacting selectively and non-covalently with any protease or peptidase.
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GO Term
GO:0097240 | chromosome attachment to the nuclear envelope
Description: The process in which chromatin is anchored to the nuclear envelope.
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GO Term
GO:0018818 | acetylene hydratase activity
Description: Catalysis of the reaction: acetaldehyde = acetylene + H(2)O.
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GO Term
GO:0007281 | germ cell development
Description: The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
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GO Term
GO:0045450 | bicoid mRNA localization
Description: Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.
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GO Term
GO:0048019 | receptor antagonist activity
Description: The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
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GO Term
GO:0016589 | NURF complex
Description: An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.
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GO Term
GO:0002039 | p53 binding
Description: Interacting selectively and non-covalently with one of the p53 family of proteins.
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GO Term
GO:0071564 | npBAF complex
Description: A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.
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GO Term
GO:0034472 | snRNA 3'-end processing
Description: Any process involved in forming the mature 3' end of an snRNA molecule.
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GO Term
GO:0031157 | regulation of aggregate size involved in sorocarp development
Description: Any process that modulates the size of the aggregate formed during sorocarp formation.
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GO Term
GO:0038066 | p38MAPK cascade
Description: An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
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GO Term
GO:0010082 | regulation of root meristem growth
Description: Any process involved in maintaining the size and shape of a root meristem.
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GO Term
GO:0045216 | cell-cell junction organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
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GO Term
GO:0032609 | interferon-gamma production
Description: The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.
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GO Term
GO:2000404 | regulation of T cell migration
Description: Any process that modulates the frequency, rate or extent of T cell migration.
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GO Term
GO:0033235 | positive regulation of protein sumoylation
Description: Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
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GO Term
GO:1902073 | positive regulation of hypoxia-inducible factor-1alpha signaling pathway
Description: Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
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GO Term
GO:0032486 | Rap protein signal transduction
Description: A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
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GO Term
GO:0009909 | regulation of flower development
Description: Any process that modulates the frequency, rate or extent of flower development.
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GO Term
GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Description: The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
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GO Term
GO:0007624 | ultradian rhythm
Description: The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours.
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GO Term
GO:0019408 | dolichol biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
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GO Term
GO:1904423 | dehydrodolichyl diphosphate synthase complex
Description: A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.
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GO Term
GO:0015929 | hexosaminidase activity
Description: Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.
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GO Term
GO:0034474 | U2 snRNA 3'-end processing
Description: Any process involved in forming the mature 3' end of a U2 snRNA molecule.
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GO Term
GO:0019863 | IgE binding
Description: Interacting selectively and non-covalently with an immunoglobulin of the IgE isotype.
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GO Term
GO:0045162 | clustering of voltage-gated sodium channels
Description: The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.
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GO Term
GO:1902017 | regulation of cilium assembly
Description: Any process that modulates the frequency, rate or extent of cilium assembly.
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GO Term
GO:0014066 | regulation of phosphatidylinositol 3-kinase signaling
Description: Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
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GO Term
GO:0009630 | gravitropism
Description: The orientation of plant parts under the stimulation of gravity.
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GO Term
GO:2000012 | regulation of auxin polar transport
Description: Any process that modulates the frequency, rate or extent of auxin polar transport.
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GO Term
GO:0006970 | response to osmotic stress
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
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GO Term
GO:0006995 | cellular response to nitrogen starvation
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
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