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Search results 2301 to 2400 out of 44733 for *

Category restricted to GOTerm (x)

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Category: GOTerm
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Type Details Score
GO Term
GO:0007519 | skeletal muscle tissue development
Description: The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
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GO Term
GO:0048741 | skeletal muscle fiber development
Description: The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
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GO Term
GO:0061702 | inflammasome complex
Description: A cytosolic protein complex that is capable of activating caspase-1.
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GO Term
GO:1902808 | positive regulation of cell cycle G1/S phase transition
Description: Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
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GO Term
GO:0019740 | nitrogen utilization
Description: A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.
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GO Term
GO:0034340 | response to type I interferon
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
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GO Term
GO:0060337 | type I interferon signaling pathway
Description: A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
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GO Term
GO:1990822 | basic amino acid transmembrane transport
Description: The directed movement of basic amino acids from one side of a membrane to the other.
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GO Term
GO:0042611 | MHC protein complex
Description: A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.
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GO Term
GO:0004157 | dihydropyrimidinase activity
Description: Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.
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GO Term
GO:0050828 | regulation of liquid surface tension
Description: Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid.
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GO Term
GO:0007263 | nitric oxide mediated signal transduction
Description: Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.
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GO Term
GO:0031672 | A band
Description: The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
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GO Term
GO:0032465 | regulation of cytokinesis
Description: Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
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GO Term
GO:0010154 | fruit development
Description: The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.
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GO Term
GO:0008218 | bioluminescence
Description: The production of light by certain enzyme-catalyzed reactions in cells.
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GO Term
GO:0016837 | carbon-oxygen lyase activity, acting on polysaccharides
Description: Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.
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GO Term
GO:0005044 | scavenger receptor activity
Description: Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).
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GO Term
GO:0008200 | ion channel inhibitor activity
Description: Stops, prevents, or reduces the activity of an ion channel.
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GO Term
GO:0009111 | vitamin catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
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GO Term
GO:0048311 | mitochondrion distribution
Description: Any process that establishes the spatial arrangement of mitochondria between and within cells.
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GO Term
GO:0048308 | organelle inheritance
Description: The partitioning of organelles between daughter cells at cell division.
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GO Term
GO:0051646 | mitochondrion localization
Description: Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
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GO Term
GO:0008150 | biological_process
Description: A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
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GO Term
GO:0000006 | high-affinity zinc transmembrane transporter activity
Description: Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
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GO Term
GO:0003674 | molecular_function
Description: A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.
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GO Term
GO:0072509 | divalent inorganic cation transmembrane transporter activity
Description: Enables the transfer of inorganic cations with a valency of two from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
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GO Term
GO:0046915 | transition metal ion transmembrane transporter activity
Description: Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
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GO Term
GO:0000007 | low-affinity zinc ion transmembrane transporter activity
Description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
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GO Term
GO:0000010 | trans-hexaprenyltranstransferase activity
Description: Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate.
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GO Term
GO:0000014 | single-stranded DNA endodeoxyribonuclease activity
Description: Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.
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GO Term
GO:0005575 | cellular_component
Description: A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).
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GO Term
GO:0000016 | lactase activity
Description: Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.
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GO Term
GO:0042946 | glucoside transport
Description: The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue.
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GO Term
GO:0000017 | alpha-glucoside transport
Description: The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.
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GO Term
GO:1901656 | glycoside transport
Description: The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0000019 | regulation of mitotic recombination
Description: Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.
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GO Term
GO:0000022 | mitotic spindle elongation
Description: The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
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GO Term
GO:0051231 | spindle elongation
Description: The cell cycle process in which the distance is lengthened between poles of the spindle.
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GO Term
GO:0000023 | maltose metabolic process
Description: The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.
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GO Term
GO:0046351 | disaccharide biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units.
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GO Term
GO:0000024 | maltose biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).
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GO Term
GO:0046352 | disaccharide catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units.
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GO Term
GO:0000025 | maltose catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).
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GO Term
GO:0009313 | oligosaccharide catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
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GO Term
GO:0000026 | alpha-1,2-mannosyltransferase activity
Description: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.
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GO Term
GO:0000028 | ribosomal small subunit assembly
Description: The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
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GO Term
GO:0000031 | mannosylphosphate transferase activity
Description: Catalysis of the transfer of a mannosylphosphate group from one compound to another.
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GO Term
GO:0006057 | mannoprotein biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of mannoproteins, any protein that contains covalently bound mannose residues.
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GO Term
GO:0000032 | cell wall mannoprotein biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.
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GO Term
GO:0031506 | cell wall glycoprotein biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.
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GO Term
GO:0006056 | mannoprotein metabolic process
Description: The chemical reactions and pathways involving mannoproteins, any protein that contains covalently bound mannose residues.
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GO Term
GO:0000033 | alpha-1,3-mannosyltransferase activity
Description: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.
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GO Term
GO:0000035 | acyl binding
Description: Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
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GO Term
GO:0044620 | ACP phosphopantetheine attachment site binding
Description: Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).
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GO Term
GO:0051192 | prosthetic group binding
Description: Interacting selectively and non-covalently with a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
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GO Term
GO:0000048 | peptidyltransferase activity
Description: Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2).
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GO Term
GO:0000050 | urea cycle
Description: The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.
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GO Term
GO:0071941 | nitrogen cycle metabolic process
Description: A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.
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GO Term
GO:0000052 | citrulline metabolic process
Description: The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
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GO Term
GO:0000053 | argininosuccinate metabolic process
Description: The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate.
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GO Term
GO:0072350 | tricarboxylic acid metabolic process
Description: The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).
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GO Term
GO:0071428 | rRNA-containing ribonucleoprotein complex export from nucleus
Description: The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm.
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GO Term
GO:0033750 | ribosome localization
Description: A process in which a ribosome is transported to, and/or maintained in, a specific location.
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GO Term
GO:0071166 | ribonucleoprotein complex localization
Description: Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.
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GO Term
GO:0071426 | ribonucleoprotein complex export from nucleus
Description: The directed movement of a ribonucleoprotein complex from the nucleus to the cytoplasm.
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GO Term
GO:1901567 | fatty acid derivative binding
Description: Interacting selectively and non-covalently with fatty acid derivative.
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GO Term
GO:0000064 | L-ornithine transmembrane transporter activity
Description: Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.
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GO Term
GO:0110100 | spindle pole body separation
Description: The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.
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GO Term
GO:0000073 | initial mitotic spindle pole body separation
Description: The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB.
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GO Term
GO:0061804 | mitotic spindle formation (spindle phase one)
Description: The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.
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GO Term
GO:1905047 | mitotic spindle pole body organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body.
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GO Term
GO:0051300 | spindle pole body organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.
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GO Term
GO:1904029 | regulation of cyclin-dependent protein kinase activity
Description: Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity.
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GO Term
GO:0051318 | G1 phase
Description: The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.
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GO Term
GO:0000080 | mitotic G1 phase
Description: The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.
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GO Term
GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle
Description: Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
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GO Term
GO:0000084 | mitotic S phase
Description: The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.
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GO Term
GO:0051320 | S phase
Description: The cell cycle phase, following G1, during which DNA synthesis takes place.
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GO Term
GO:0051319 | G2 phase
Description: The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).
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GO Term
GO:0000085 | mitotic G2 phase
Description: The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.
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GO Term
GO:0000087 | mitotic M phase
Description: A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.
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GO Term
GO:0051324 | prophase
Description: The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
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GO Term
GO:0000088 | mitotic prophase
Description: The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
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GO Term
GO:0000089 | mitotic metaphase
Description: The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.
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GO Term
GO:0051323 | metaphase
Description: The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.
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GO Term
GO:0000090 | mitotic anaphase
Description: The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.
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GO Term
GO:0051322 | anaphase
Description: The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.
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GO Term
GO:0000091 | mitotic anaphase A
Description: The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis.
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GO Term
GO:0000092 | mitotic anaphase B
Description: The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.
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GO Term
GO:0000093 | mitotic telophase
Description: The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
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GO Term
GO:1901682 | sulfur compound transmembrane transporter activity
Description: Enables the transfer of a sulfur compound from one side of a membrane to the other.
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GO Term
GO:0000095 | S-adenosyl-L-methionine transmembrane transporter activity
Description: Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
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GO Term
GO:0051185 | coenzyme transmembrane transporter activity
Description: Enables the transfer of a coenzyme from one side of a membrane to the other. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
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GO Term
GO:0051184 | cofactor transmembrane transporter activity
Description: Enables the transfer of a cofactor from one side of a membrane to the other. A cofactor is a substance that is required for the activity of an enzyme or other protein.
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GO Term
GO:0044272 | sulfur compound biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
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GO Term
GO:0000097 | sulfur amino acid biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
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GO Term
GO:0000098 | sulfur amino acid catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
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GO Term
GO:0000099 | sulfur amino acid transmembrane transporter activity
Description: Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.
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GO Term
GO:0000100 | S-methylmethionine transmembrane transporter activity
Description: Enables the transfer of S-methylmethionine from one side of a membrane to the other.
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