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Search results 901 to 1000 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0008237 | metallopeptidase activity
Description: Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
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GO Term
GO:0031012 | extracellular matrix
Description: A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
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GO Term
GO:0048529 | magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity
Description: Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O.
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GO Term
GO:0016180 | snRNA processing
Description: Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.
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GO Term
GO:0032039 | integrator complex
Description: A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
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GO Term
GO:0032784 | regulation of DNA-templated transcription, elongation
Description: Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
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GO Term
GO:0004134 | 4-alpha-glucanotransferase activity
Description: Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
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GO Term
GO:0016866 | intramolecular transferase activity
Description: Catalysis of the transfer of a functional group from one position to another within a single molecule.
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GO Term
GO:0016579 | protein deubiquitination
Description: The removal of one or more ubiquitin groups from a protein.
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GO Term
GO:0003918 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
Description: Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
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GO Term
GO:0006265 | DNA topological change
Description: The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
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GO Term
GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity
Description: Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+).
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GO Term
GO:0015930 | glutamate synthase activity
Description: Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.
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GO Term
GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors
Description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
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GO Term
GO:0004735 | pyrroline-5-carboxylate reductase activity
Description: Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.
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GO Term
GO:0000266 | mitochondrial fission
Description: The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
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GO Term
GO:0004121 | cystathionine beta-lyase activity
Description: Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.
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GO Term
GO:0071266 | 'de novo' L-methionine biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components.
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GO Term
GO:0016844 | strictosidine synthase activity
Description: Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine.
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GO Term
GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity
Description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol.
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GO Term
GO:0009690 | cytokinin metabolic process
Description: The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.
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GO Term
GO:0019139 | cytokinin dehydrogenase activity
Description: Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.
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GO Term
GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity
Description: Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
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GO Term
GO:0006072 | glycerol-3-phosphate metabolic process
Description: The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
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GO Term
GO:0009331 | glycerol-3-phosphate dehydrogenase complex
Description: An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.
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GO Term
GO:0046168 | glycerol-3-phosphate catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.
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GO Term
GO:0006353 | DNA-templated transcription, termination
Description: The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
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GO Term
GO:0006878 | cellular copper ion homeostasis
Description: Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
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GO Term
GO:0002098 | tRNA wobble uridine modification
Description: The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
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GO Term
GO:0034227 | tRNA thio-modification
Description: The addition a sulfur atom to a nucleotide in a tRNA molecule.
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GO Term
GO:0004385 | guanylate kinase activity
Description: Catalysis of the reaction: ATP + GMP = ADP + GDP.
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GO Term
GO:0006163 | purine nucleotide metabolic process
Description: The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
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GO Term
GO:0004019 | adenylosuccinate synthase activity
Description: Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.
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GO Term
GO:0006164 | purine nucleotide biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
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GO Term
GO:0003747 | translation release factor activity
Description: Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
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GO Term
GO:0000213 | tRNA-intron endonuclease activity
Description: Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
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GO Term
GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation
Description: Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
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GO Term
GO:0000902 | cell morphogenesis
Description: The developmental process in which the size or shape of a cell is generated and organized.
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GO Term
GO:0030915 | Smc5-Smc6 complex
Description: A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.
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GO Term
GO:0009790 | embryo development
Description: The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
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GO Term
GO:0001671 | ATPase activator activity
Description: Binds to and increases the ATP hydrolysis activity of an ATPase.
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GO Term
GO:0003905 | alkylbase DNA N-glycosylase activity
Description: Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.
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GO Term
GO:0016872 | intramolecular lyase activity
Description: The catalysis of certain rearrangements of a molecule to break or form a ring.
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GO Term
GO:0008380 | RNA splicing
Description: The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
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GO Term
GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine
Description: The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
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GO Term
GO:0019135 | deoxyhypusine monooxygenase activity
Description: Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
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GO Term
GO:0006471 | protein ADP-ribosylation
Description: The transfer, from NAD, of ADP-ribose to protein amino acids.
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GO Term
GO:0010038 | response to metal ion
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
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GO Term
GO:0016756 | glutathione gamma-glutamylcysteinyltransferase activity
Description: Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.
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GO Term
GO:0046938 | phytochelatin biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
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GO Term
GO:0006069 | ethanol oxidation
Description: An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.
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GO Term
GO:0051903 | S-(hydroxymethyl)glutathione dehydrogenase activity
Description: Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
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GO Term
GO:0043622 | cortical microtubule organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.
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GO Term
GO:0008837 | diaminopimelate epimerase activity
Description: Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.
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GO Term
GO:0000105 | histidine biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
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GO Term
GO:0003879 | ATP phosphoribosyltransferase activity
Description: Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.
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GO Term
GO:0004017 | adenylate kinase activity
Description: Catalysis of the reaction: ATP + AMP = 2 ADP.
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GO Term
GO:0030515 | snoRNA binding
Description: Interacting selectively and non-covalently with small nucleolar RNA.
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GO Term
GO:0072588 | box H/ACA RNP complex
Description: A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex.
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GO Term
GO:0005484 | SNAP receptor activity
Description: Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
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GO Term
GO:0016471 | vacuolar proton-transporting V-type ATPase complex
Description: A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
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GO Term
GO:0008836 | diaminopimelate decarboxylase activity
Description: Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2).
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GO Term
GO:0006559 | L-phenylalanine catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.
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GO Term
GO:0004001 | adenosine kinase activity
Description: Catalysis of the reaction: ATP + adenosine = ADP + AMP.
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GO Term
GO:0006166 | purine ribonucleoside salvage
Description: Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
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GO Term
GO:0016987 | sigma factor activity
Description: Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
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GO Term
GO:0004821 | histidine-tRNA ligase activity
Description: Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).
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GO Term
GO:0006427 | histidyl-tRNA aminoacylation
Description: The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA.
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GO Term
GO:0004478 | methionine adenosyltransferase activity
Description: Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.
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GO Term
GO:0006556 | S-adenosylmethionine biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
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GO Term
GO:0006777 | Mo-molybdopterin cofactor biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
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GO Term
GO:0004332 | fructose-bisphosphate aldolase activity
Description: Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
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GO Term
GO:0003844 | 1,4-alpha-glucan branching enzyme activity
Description: Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.
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GO Term
GO:0005978 | glycogen biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
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GO Term
GO:0097361 | CIA complex
Description: The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.
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GO Term
GO:0005750 | mitochondrial respiratory chain complex III
Description: A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.
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GO Term
GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c
Description: The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III.
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GO Term
GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters
Description: Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
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GO Term
GO:0004150 | dihydroneopterin aldolase activity
Description: Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde.
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GO Term
GO:0006760 | folic acid-containing compound metabolic process
Description: The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
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GO Term
GO:0004140 | dephospho-CoA kinase activity
Description: Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+).
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GO Term
GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity
Description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH.
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GO Term
GO:0009396 | folic acid-containing compound biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.
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GO Term
GO:0004788 | thiamine diphosphokinase activity
Description: Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.
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GO Term
GO:0006772 | thiamine metabolic process
Description: The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
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GO Term
GO:0009229 | thiamine diphosphate biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
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GO Term
GO:0006338 | chromatin remodeling
Description: Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
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GO Term
GO:0035267 | NuA4 histone acetyltransferase complex
Description: A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).
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GO Term
GO:0043967 | histone H4 acetylation
Description: The modification of histone H4 by the addition of an acetyl group.
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GO Term
GO:0043968 | histone H2A acetylation
Description: The modification of histone H2A by the addition of an acetyl group.
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GO Term
GO:0006808 | regulation of nitrogen utilization
Description: Any process that modulates the frequency, rate or extent of nitrogen utilization.
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GO Term
GO:0004827 | proline-tRNA ligase activity
Description: Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
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GO Term
GO:0006433 | prolyl-tRNA aminoacylation
Description: The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA.
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GO Term
GO:0008878 | glucose-1-phosphate adenylyltransferase activity
Description: Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate.
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GO Term
GO:0050790 | regulation of catalytic activity
Description: Any process that modulates the activity of an enzyme.
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GO Term
GO:0004345 | glucose-6-phosphate dehydrogenase activity
Description: Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
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GO Term
GO:0006006 | glucose metabolic process
Description: The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
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GO Term
GO:0033926 | glycopeptide alpha-N-acetylgalactosaminidase activity
Description: Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins.
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GO Term
GO:0008061 | chitin binding
Description: Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
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GO Term
GO:0004813 | alanine-tRNA ligase activity
Description: Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
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