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Search results 42501 to 42600 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:2000042 | negative regulation of double-strand break repair via homologous recombination
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.
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GO Term
GO:0061635 | regulation of protein complex stability
Description: Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly.
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GO Term
GO:0031641 | regulation of myelination
Description: Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
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GO Term
GO:0033270 | paranode region of axon
Description: An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.
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GO Term
GO:0043220 | Schmidt-Lanterman incisure
Description: Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier.
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GO Term
GO:0070300 | phosphatidic acid binding
Description: Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
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GO Term
GO:0042793 | plastid transcription
Description: The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase.
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GO Term
GO:0000427 | plastid-encoded plastid RNA polymerase complex
Description: An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition.
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GO Term
GO:0000974 | Prp19 complex
Description: A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.
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GO Term
GO:0042644 | chloroplast nucleoid
Description: The region of a chloroplast to which the DNA is confined.
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GO Term
GO:0019566 | arabinose metabolic process
Description: The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.
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GO Term
GO:0035103 | sterol regulatory element binding protein cleavage
Description: The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids.
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GO Term
GO:0044695 | Dsc E3 ubiquitin ligase complex
Description: An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.
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GO Term
GO:0032300 | mismatch repair complex
Description: Any complex formed of proteins that act in mismatch repair.
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GO Term
GO:0019991 | septate junction assembly
Description: The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.
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GO Term
GO:0070824 | SHREC complex
Description: A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.
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GO Term
GO:0033255 | SAS acetyltransferase complex
Description: A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.
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GO Term
GO:0032150 | ubiquinone biosynthetic process from chorismate
Description: The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.
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GO Term
GO:0039678 | viral genome ejection through host cell envelope
Description: Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm.
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GO Term
GO:0099002 | viral genome ejection through host cell envelope, short tail mechanism
Description: Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties.
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GO Term
GO:0046798 | viral portal complex
Description: A multimeric ring of proteins through which the DNA enters and exits the viral capsid.
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GO Term
GO:0005158 | insulin receptor binding
Description: Interacting selectively and non-covalently with the insulin receptor.
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GO Term
GO:0008286 | insulin receptor signaling pathway
Description: The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
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GO Term
GO:0050355 | triphosphatase activity
Description: Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.
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GO Term
GO:0007520 | myoblast fusion
Description: A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
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GO Term
GO:0060538 | skeletal muscle organ development
Description: The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.
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GO Term
GO:1904684 | negative regulation of metalloendopeptidase activity
Description: Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity.
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GO Term
GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity
Description: Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.
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GO Term
GO:0062101 | peptidyl-aspartic acid 3-dioxygenase activity
Description: Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2.
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GO Term
GO:0042264 | peptidyl-aspartic acid hydroxylation
Description: The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid.
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GO Term
GO:0022008 | neurogenesis
Description: Generation of cells within the nervous system.
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GO Term
GO:0106050 | tRNA 2'-O-methyltransferase activity
Description: Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.
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GO Term
GO:0006408 | snRNA export from nucleus
Description: The directed movement of snRNA from the nucleus to the cytoplasm.
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GO Term
GO:0030891 | VCB complex
Description: A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.
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GO Term
GO:0035023 | regulation of Rho protein signal transduction
Description: Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
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GO Term
GO:0090173 | regulation of synaptonemal complex assembly
Description: Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.
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GO Term
GO:0031396 | regulation of protein ubiquitination
Description: Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.
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GO Term
GO:0001889 | liver development
Description: The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
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GO Term
GO:0030073 | insulin secretion
Description: The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
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GO Term
GO:0031016 | pancreas development
Description: The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
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GO Term
GO:0009749 | response to glucose
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
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GO Term
GO:0042304 | regulation of fatty acid biosynthetic process
Description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.
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GO Term
GO:0050796 | regulation of insulin secretion
Description: Any process that modulates the frequency, rate or extent of the regulated release of insulin.
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GO Term
GO:0060326 | cell chemotaxis
Description: The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
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GO Term
GO:0002250 | adaptive immune response
Description: An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
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GO Term
GO:0032732 | positive regulation of interleukin-1 production
Description: Any process that activates or increases the frequency, rate, or extent of interleukin-1 production.
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GO Term
GO:0090222 | centrosome-templated microtubule nucleation
Description: The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.
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GO Term
GO:0046627 | negative regulation of insulin receptor signaling pathway
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
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GO Term
GO:0051881 | regulation of mitochondrial membrane potential
Description: Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
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GO Term
GO:0061929 | gamma-glutamylaminecyclotransferase activity
Description: Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline.
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GO Term
GO:0017065 | single-strand selective uracil DNA N-glycosylase activity
Description: Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
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GO Term
GO:0004679 | AMP-activated protein kinase activity
Description: Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.
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GO Term
GO:0004343 | glucosamine 6-phosphate N-acetyltransferase activity
Description: Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+).
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GO Term
GO:0006392 | transcription elongation from mitochondrial promoter
Description: The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.
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GO Term
GO:0001736 | establishment of planar polarity
Description: Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
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GO Term
GO:0030295 | protein kinase activator activity
Description: Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.
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GO Term
GO:0030010 | establishment of cell polarity
Description: The specification and formation of anisotropic intracellular organization or cell growth patterns.
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GO Term
GO:0042593 | glucose homeostasis
Description: Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
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GO Term
GO:0090149 | mitochondrial membrane fission
Description: A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission.
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GO Term
GO:0000712 | resolution of meiotic recombination intermediates
Description: The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.
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GO Term
GO:0047486 | chondroitin ABC lyase activity
Description: Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.
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GO Term
GO:0006027 | glycosaminoglycan catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
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GO Term
GO:0032571 | response to vitamin K
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.
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GO Term
GO:0060348 | bone development
Description: The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
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GO Term
GO:1900076 | regulation of cellular response to insulin stimulus
Description: Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus.
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GO Term
GO:0001708 | cell fate specification
Description: The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
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GO Term
GO:0034128 | negative regulation of MyD88-independent toll-like receptor signaling pathway
Description: Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
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GO Term
GO:0048678 | response to axon injury
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
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GO Term
GO:0019433 | triglyceride catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
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GO Term
GO:0008420 | RNA polymerase II CTD heptapeptide repeat phosphatase activity
Description: Catalysis of the reaction: phospho-(DNA-directed RNA polymerase II) + H2O = (DNA-directed RNA polymerase II) + phosphate.
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GO Term
GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain
Description: The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.
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GO Term
GO:0071930 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle
Description: Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle.
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GO Term
GO:0030291 | protein serine/threonine kinase inhibitor activity
Description: Stops, prevents or reduces the activity of a protein serine/threonine kinase.
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GO Term
GO:0016554 | cytidine to uridine editing
Description: The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
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GO Term
GO:0035662 | Toll-like receptor 4 binding
Description: Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
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GO Term
GO:0055087 | Ski complex
Description: A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p.
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GO Term
GO:0018095 | protein polyglutamylation
Description: The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.
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GO Term
GO:0002768 | immune response-regulating cell surface receptor signaling pathway
Description: A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.
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GO Term
GO:0009627 | systemic acquired resistance
Description: The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.
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GO Term
GO:0032196 | transposition
Description: Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.
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GO Term
GO:0071209 | U7 snRNA binding
Description: Interacting selectively and non-covalently with the U7 small nuclear RNA (U7 snRNA).
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GO Term
GO:1990456 | mitochondrion-endoplasmic reticulum membrane tethering
Description: The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.
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GO Term
GO:0044233 | mitochondria-associated endoplasmic reticulum membrane
Description: A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.
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GO Term
GO:0048578 | positive regulation of long-day photoperiodism, flowering
Description: Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
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GO Term
GO:0098869 | cellular oxidant detoxification
Description: Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
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GO Term
GO:0043592 | exosporium
Description: The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid.
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GO Term
GO:0045041 | protein import into mitochondrial intermembrane space
Description: The import of proteins into the space between the inner and outer mitochondrial membranes.
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GO Term
GO:0035196 | production of miRNAs involved in gene silencing by miRNA
Description: Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.
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GO Term
GO:1903730 | regulation of phosphatidate phosphatase activity
Description: Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity.
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GO Term
GO:0007232 | osmosensory signaling pathway via Sho1 osmosensor
Description: A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.
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GO Term
GO:0010088 | phloem development
Description: The formation of the principal food-conducting tissue of a vascular plant.
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GO Term
GO:0007142 | male meiosis II
Description: A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.
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GO Term
GO:0080162 | intracellular auxin transport
Description: The directed movement of auxins within a cell. Auxins are a group of plant hormones that regulates aspects of plant growth.
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GO Term
GO:1900034 | regulation of cellular response to heat
Description: Any process that modulates the frequency, rate or extent of cellular response to heat.
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GO Term
GO:0045168 | cell-cell signaling involved in cell fate commitment
Description: Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.
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GO Term
GO:0030544 | Hsp70 protein binding
Description: Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
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GO Term
GO:0009787 | regulation of abscisic acid-activated signaling pathway
Description: Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling.
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GO Term
GO:0010100 | negative regulation of photomorphogenesis
Description: Any process that stops, reduces or prevents photomorphogenesis.
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GO Term
GO:0001681 | sialate O-acetylesterase activity
Description: Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.
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GO Term
GO:1903259 | exon-exon junction complex disassembly
Description: The disaggregation of an exon-exon junction complex into its constituent components.
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