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Search results 42601 to 42700 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0051091 | positive regulation of DNA-binding transcription factor activity
Description: Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
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GO Term
GO:0043063 | intercellular bridge organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.
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GO Term
GO:0051306 | mitotic sister chromatid separation
Description: The process in which sister chromatids are physically detached from each other during mitosis.
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GO Term
GO:1901537 | positive regulation of DNA demethylation
Description: Any process that activates or increases the frequency, rate or extent of DNA demethylation.
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GO Term
GO:0002953 | 5'-deoxynucleotidase activity
Description: Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate.
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GO Term
GO:0016980 | creatinase activity
Description: Catalysis of the reaction: creatine + H(2)O = sarcosine + urea.
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GO Term
GO:1990593 | nascent polypeptide-associated complex binding
Description: Interacting selectively and non-covalently with the nascent polypeptide-associated complex, which is a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.
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GO Term
GO:0010374 | stomatal complex development
Description: The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
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GO Term
GO:0030548 | acetylcholine receptor regulator activity
Description: Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.
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GO Term
GO:0030368 | interleukin-17 receptor activity
Description: Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
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GO Term
GO:0060548 | negative regulation of cell death
Description: Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
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GO Term
GO:0071480 | cellular response to gamma radiation
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
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GO Term
GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity
Description: Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.
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GO Term
GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment
Description: A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport.
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GO Term
GO:0033218 | amide binding
Description: Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
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GO Term
GO:0032963 | collagen metabolic process
Description: The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
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GO Term
GO:0005147 | oncostatin-M receptor binding
Description: Interacting selectively and non-covalently with the oncostatin-M receptor.
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GO Term
GO:0038165 | oncostatin-M-mediated signaling pathway
Description: A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
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GO Term
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
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GO Term
GO:0009638 | phototropism
Description: The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.
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GO Term
GO:0019210 | kinase inhibitor activity
Description: Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
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GO Term
GO:0009734 | auxin-activated signaling pathway
Description: A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
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GO Term
GO:2000762 | regulation of phenylpropanoid metabolic process
Description: Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process.
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GO Term
GO:0010227 | floral organ abscission
Description: The controlled shedding of floral organs.
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GO Term
GO:0010119 | regulation of stomatal movement
Description: Any process that modulates the frequency, rate or extent of stomatal movement.
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GO Term
GO:0047324 | phosphoenolpyruvate-glycerone phosphotransferase activity
Description: Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.
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GO Term
GO:0019563 | glycerol catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
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GO Term
GO:0015918 | sterol transport
Description: The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
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GO Term
GO:0050528 | acyloxyacyl hydrolase activity
Description: Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.
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GO Term
GO:0042007 | interleukin-18 binding
Description: Interacting selectively and non-covalently with interleukin-18.
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GO Term
GO:0005689 | U12-type spliceosomal complex
Description: Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.
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GO Term
GO:0035198 | miRNA binding
Description: Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
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GO Term
GO:0043175 | RNA polymerase core enzyme binding
Description: Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.
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GO Term
GO:0019815 | B cell receptor complex
Description: An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
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GO Term
GO:0070773 | protein-N-terminal glutamine amidohydrolase activity
Description: Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein.
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GO Term
GO:0047464 | heparosan-N-sulfate-glucuronate 5-epimerase activity
Description: Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate.
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GO Term
GO:0015012 | heparan sulfate proteoglycan biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
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GO Term
GO:0043551 | regulation of phosphatidylinositol 3-kinase activity
Description: Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring.
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GO Term
GO:0045022 | early endosome to late endosome transport
Description: The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
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GO Term
GO:0004445 | inositol-polyphosphate 5-phosphatase activity
Description: Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
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GO Term
GO:0000493 | box H/ACA snoRNP assembly
Description: The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
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GO Term
GO:0000938 | GARP complex
Description: A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles.
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GO Term
GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding
Description: Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.
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GO Term
GO:0005858 | axonemal dynein complex
Description: A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
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GO Term
GO:0001731 | formation of translation preinitiation complex
Description: The joining of the small ribosomal subunit, ternary complex, and mRNA.
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GO Term
GO:0000470 | maturation of LSU-rRNA
Description: Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.
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GO Term
GO:0071108 | protein K48-linked deubiquitination
Description: A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
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GO Term
GO:0072659 | protein localization to plasma membrane
Description: A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
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GO Term
GO:0006780 | uroporphyrinogen III biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of uroporphyrinogen III.
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GO Term
GO:1990116 | ribosome-associated ubiquitin-dependent protein catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein.
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GO Term
GO:1990112 | RQC complex
Description: A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
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GO Term
GO:0106035 | protein maturation by [4Fe-4S] cluster transfer
Description: The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
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GO Term
GO:0016971 | flavin-linked sulfhydryl oxidase activity
Description: Catalysis of the formation of disulfide bridges.
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GO Term
GO:0004438 | phosphatidylinositol-3-phosphatase activity
Description: Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.
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GO Term
GO:0035494 | SNARE complex disassembly
Description: The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
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GO Term
GO:0010265 | SCF complex assembly
Description: The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.
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GO Term
GO:0035303 | regulation of dephosphorylation
Description: Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.
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GO Term
GO:0099122 | RNA polymerase II C-terminal domain binding
Description: Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.
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GO Term
GO:0005682 | U5 snRNP
Description: A ribonucleoprotein complex that contains small nuclear RNA U5.
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GO Term
GO:0005078 | MAP-kinase scaffold activity
Description: The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.
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GO Term
GO:0008356 | asymmetric cell division
Description: The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
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GO Term
GO:0046922 | peptide-O-fucosyltransferase activity
Description: Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.
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GO Term
GO:0036066 | protein O-linked fucosylation
Description: The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage.
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GO Term
GO:0007143 | female meiotic nuclear division
Description: A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
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GO Term
GO:0032703 | negative regulation of interleukin-2 production
Description: Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.
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GO Term
GO:0042130 | negative regulation of T cell proliferation
Description: Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
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GO Term
GO:0043031 | negative regulation of macrophage activation
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
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GO Term
GO:0019005 | SCF ubiquitin ligase complex
Description: A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
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GO Term
GO:0010485 | H4 histone acetyltransferase activity
Description: Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
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GO Term
GO:0043998 | H2A histone acetyltransferase activity
Description: Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.
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GO Term
GO:0048658 | anther wall tapetum development
Description: The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure.
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GO Term
GO:0051017 | actin filament bundle assembly
Description: The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
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GO Term
GO:0030628 | pre-mRNA 3'-splice site binding
Description: Interacting selectively and non-covalently with the pre-mRNA 3' splice site sequence.
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GO Term
GO:0051879 | Hsp90 protein binding
Description: Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
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GO Term
GO:0033781 | cholesterol 24-hydroxylase activity
Description: Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+).
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GO Term
GO:0047631 | ADP-ribose diphosphatase activity
Description: Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.
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GO Term
GO:0000347 | THO complex
Description: The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.
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GO Term
GO:0150077 | regulation of neuroinflammatory response
Description: Any process that modulates the frequency, rate or extent of neuroinflammatory response.
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GO Term
GO:0006611 | protein export from nucleus
Description: The directed movement of a protein from the nucleus into the cytoplasm.
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GO Term
GO:0006409 | tRNA export from nucleus
Description: The directed movement of tRNA from the nucleus to the cytoplasm.
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GO Term
GO:0071528 | tRNA re-export from nucleus
Description: The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.
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GO Term
GO:0009421 | bacterial-type flagellum filament cap
Description: The proteinaceous structure at the distal tip of the bacterial-type flagellar filament.
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GO Term
GO:0036377 | arbuscular mycorrhizal association
Description: A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil.
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GO Term
GO:0000076 | DNA replication checkpoint
Description: A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
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GO Term
GO:0000422 | autophagy of mitochondrion
Description: The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.
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GO Term
GO:0030979 | alpha-glucan biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
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GO Term
GO:0035721 | intraciliary retrograde transport
Description: The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.
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GO Term
GO:1990745 | EARP complex
Description: A quatrefoil tethering complex required for endocytic recycling.
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GO Term
GO:0035368 | selenocysteine insertion sequence binding
Description: Interacting selectively and non-covalently with the selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.
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GO Term
GO:0034066 | RIC1-RGP1 guanyl-nucleotide exchange factor complex
Description: A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.
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GO Term
GO:0071786 | endoplasmic reticulum tubular network organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.
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GO Term
GO:0045639 | positive regulation of myeloid cell differentiation
Description: Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.
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GO Term
GO:0040027 | negative regulation of vulval development
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
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GO Term
GO:0140053 | mitochondrial gene expression
Description: The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
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GO Term
GO:0045727 | positive regulation of translation
Description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
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GO Term
GO:0070579 | methylcytosine dioxygenase activity
Description: Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2.
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GO Term
GO:0006211 | 5-methylcytosine catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA.
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GO Term
GO:0080111 | DNA demethylation
Description: The removal of a methyl group from one or more nucleotides within an DNA molecule.
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GO Term
GO:0006998 | nuclear envelope organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
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GO Term
GO:0035458 | cellular response to interferon-beta
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
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