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Search results 42701 to 42800 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0009959 | negative gravitropism
Description: The orientation of plant parts away from gravity.
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GO Term
GO:0007095 | mitotic G2 DNA damage checkpoint
Description: A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
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GO Term
GO:0097501 | stress response to metal ion
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus.
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GO Term
GO:0001091 | RNA polymerase II general transcription initiation factor binding
Description: Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
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GO Term
GO:1900150 | regulation of defense response to fungus
Description: Any process that modulates the frequency, rate or extent of defense response to fungus.
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GO Term
GO:0035101 | FACT complex
Description: An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer.
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GO Term
GO:0010497 | plasmodesmata-mediated intercellular transport
Description: The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
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GO Term
GO:0010115 | regulation of abscisic acid biosynthetic process
Description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.
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GO Term
GO:0000911 | cytokinesis by cell plate formation
Description: The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana.
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GO Term
GO:0080183 | response to photooxidative stress
Description: Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
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GO Term
GO:0032480 | negative regulation of type I interferon production
Description: Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
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GO Term
GO:0039536 | negative regulation of RIG-I signaling pathway
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.
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GO Term
GO:0032120 | ascospore-type prospore membrane assembly
Description: The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.
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GO Term
GO:0033551 | monopolin complex
Description: A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits.
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GO Term
GO:0080143 | regulation of amino acid export
Description: Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle.
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GO Term
GO:0003691 | double-stranded telomeric DNA binding
Description: Interacting selectively and non-covalently with double-stranded telomere-associated DNA.
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GO Term
GO:1900364 | negative regulation of mRNA polyadenylation
Description: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation.
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GO Term
GO:0031053 | primary miRNA processing
Description: Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.
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GO Term
GO:0070877 | microprocessor complex
Description: A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs.
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GO Term
GO:0009786 | regulation of asymmetric cell division
Description: Any process that modulates the frequency, rate or extent of asymmetric cell division.
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GO Term
GO:0032875 | regulation of DNA endoreduplication
Description: Any process that modulates the frequency, rate or extent of DNA endoreduplication.
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GO Term
GO:0000900 | translation repressor activity, mRNA regulatory element binding
Description: Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
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GO Term
GO:0006997 | nucleus organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
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GO Term
GO:0036396 | RNA N6-methyladenosine methyltransferase complex
Description: A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).
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GO Term
GO:0000127 | transcription factor TFIIIC complex
Description: A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.
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GO Term
GO:0042753 | positive regulation of circadian rhythm
Description: Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.
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GO Term
GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type II
Description: A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.
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GO Term
GO:1901998 | toxin transport
Description: The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0010098 | suspensor development
Description: The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm.
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GO Term
GO:0043177 | organic acid binding
Description: Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage.
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GO Term
GO:0015849 | organic acid transport
Description: The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0032482 | Rab protein signal transduction
Description: A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.
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GO Term
GO:0004661 | protein geranylgeranyltransferase activity
Description: Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein.
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GO Term
GO:0005953 | CAAX-protein geranylgeranyltransferase complex
Description: A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane.
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GO Term
GO:0050277 | sedoheptulokinase activity
Description: Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate.
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GO Term
GO:1901981 | phosphatidylinositol phosphate binding
Description: Interacting selectively and non-covalently with phosphatidylinositol phosphate.
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GO Term
GO:0009083 | branched-chain amino acid catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
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GO Term
GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity
Description: Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
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GO Term
GO:0140223 | general transcription initiation factor activity
Description: An activity that contributes to transcription start site selection and transcription initiation.
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GO Term
GO:0017054 | negative cofactor 2 complex
Description: A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.
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GO Term
GO:0006283 | transcription-coupled nucleotide-excision repair
Description: The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
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GO Term
GO:0047173 | phosphatidylcholine-retinol O-acyltransferase activity
Description: Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine.
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GO Term
GO:0042572 | retinol metabolic process
Description: The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
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GO Term
GO:0097198 | histone H3-K36 trimethylation
Description: The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone.
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GO Term
GO:1900745 | positive regulation of p38MAPK cascade
Description: Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.
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GO Term
GO:0071765 | nuclear inner membrane organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.
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GO Term
GO:0070692 | CTDK-1 complex
Description: A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).
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GO Term
GO:1902412 | regulation of mitotic cytokinesis
Description: Any process that modulates the frequency, rate or extent of mitotic cytokinesis.
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GO Term
GO:0030098 | lymphocyte differentiation
Description: The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
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GO Term
GO:0019767 | IgE receptor activity
Description: Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
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GO Term
GO:0032998 | Fc-epsilon receptor I complex
Description: A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE.
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GO Term
GO:0002322 | B cell proliferation involved in immune response
Description: The expansion of a B cell population by cell division following B cell activation during an immune response.
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GO Term
GO:0050864 | regulation of B cell activation
Description: Any process that modulates the frequency, rate or extent of B cell activation.
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GO Term
GO:0061138 | morphogenesis of a branching epithelium
Description: The process in which the anatomical structures of a branched epithelium are generated and organized.
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GO Term
GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex
Description: A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates.
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GO Term
GO:0060340 | positive regulation of type I interferon-mediated signaling pathway
Description: Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
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GO Term
GO:0003726 | double-stranded RNA adenosine deaminase activity
Description: Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.
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GO Term
GO:0042010 | interleukin-15 receptor activity
Description: Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
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GO Term
GO:0035723 | interleukin-15-mediated signaling pathway
Description: A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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GO Term
GO:0032813 | tumor necrosis factor receptor superfamily binding
Description: Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily.
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GO Term
GO:0008179 | adenylate cyclase binding
Description: Interacting selectively and non-covalently with the enzyme adenylate cyclase.
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GO Term
GO:0045762 | positive regulation of adenylate cyclase activity
Description: Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.
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GO Term
GO:0050777 | negative regulation of immune response
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
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GO Term
GO:0002309 | T cell proliferation involved in immune response
Description: The expansion of a T cell population by cell division as part of an immune response.
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GO Term
GO:0042922 | neuromedin U receptor binding
Description: Interacting selectively and non-covalently with one or more specific sites on a neuromedin U receptor.
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GO Term
GO:0002819 | regulation of adaptive immune response
Description: Any process that modulates the frequency, rate, or extent of an adaptive immune response.
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GO Term
GO:0071787 | endoplasmic reticulum tubular network formation
Description: The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
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GO Term
GO:0047057 | vitamin-K-epoxide reductase (warfarin-sensitive) activity
Description: Catalysis of the reaction: 2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol.
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GO Term
GO:0042373 | vitamin K metabolic process
Description: The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.
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GO Term
GO:0021983 | pituitary gland development
Description: The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
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GO Term
GO:0042288 | MHC class I protein binding
Description: Interacting selectively and non-covalently with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
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GO Term
GO:0036157 | outer dynein arm
Description: Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
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GO Term
GO:0098038 | non-replicative transposition, DNA-mediated
Description: Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.
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GO Term
GO:0032798 | Swi5-Sfr1 complex
Description: A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces).
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GO Term
GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator
Description: Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
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GO Term
GO:0005881 | cytoplasmic microtubule
Description: Any microtubule in the cytoplasm of a cell.
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GO Term
GO:0050337 | thiosulfate-thiol sulfurtransferase activity
Description: Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide.
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GO Term
GO:0070221 | sulfide oxidation, using sulfide:quinone oxidoreductase
Description: A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.
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GO Term
GO:0035252 | UDP-xylosyltransferase activity
Description: Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule.
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GO Term
GO:2000781 | positive regulation of double-strand break repair
Description: Any process that activates or increases the frequency, rate or extent of double-strand break repair.
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GO Term
GO:0045503 | dynein light chain binding
Description: Interacting selectively and non-covalently with a light chain of the dynein complex.
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GO Term
GO:0045504 | dynein heavy chain binding
Description: Interacting selectively and non-covalently with a heavy chain of the dynein complex.
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GO Term
GO:0004687 | myosin light chain kinase activity
Description: Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.
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GO Term
GO:0005412 | glucose:sodium symporter activity
Description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
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GO Term
GO:0015798 | myo-inositol transport
Description: The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.
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GO Term
GO:0004711 | ribosomal protein S6 kinase activity
Description: Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.
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GO Term
GO:0021520 | spinal cord motor neuron cell fate specification
Description: The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
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GO Term
GO:0032027 | myosin light chain binding
Description: Interacting selectively and non-covalently with a light chain of a myosin complex.
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GO Term
GO:0097224 | sperm connecting piece
Description: The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum.
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GO Term
GO:1900449 | regulation of glutamate receptor signaling pathway
Description: Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway.
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GO Term
GO:0035102 | PRC1 complex
Description: A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.
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GO Term
GO:0001872 | (1->3)-beta-D-glucan binding
Description: Interacting selectively and non-covalently with (1->3)-beta-D-glucans.
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GO Term
GO:0071226 | cellular response to molecule of fungal origin
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.
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GO Term
GO:0000253 | 3-keto sterol reductase activity
Description: Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H(+).
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GO Term
GO:1901612 | cardiolipin binding
Description: Interacting selectively and non-covalently with cardiolipin.
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GO Term
GO:0002729 | positive regulation of natural killer cell cytokine production
Description: Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
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GO Term
GO:0030490 | maturation of SSU-rRNA
Description: Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
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GO Term
GO:0090161 | Golgi ribbon formation
Description: The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.
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GO Term
GO:0050727 | regulation of inflammatory response
Description: Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
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GO Term
GO:0030545 | receptor regulator activity
Description: The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed.
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