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Search results 1001 to 1100 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0006419 | alanyl-tRNA aminoacylation
Description: The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
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GO Term
GO:0006505 | GPI anchor metabolic process
Description: The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
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GO Term
GO:0006333 | chromatin assembly or disassembly
Description: The formation or destruction of chromatin structures.
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GO Term
GO:0042286 | glutamate-1-semialdehyde 2,1-aminomutase activity
Description: Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.
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GO Term
GO:0006824 | cobalt ion transport
Description: The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0015087 | cobalt ion transmembrane transporter activity
Description: Enables the transfer of cobalt (Co) ions from one side of a membrane to the other.
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GO Term
GO:0015099 | nickel cation transmembrane transporter activity
Description: Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.
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GO Term
GO:0015675 | nickel cation transport
Description: The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0004044 | amidophosphoribosyltransferase activity
Description: Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.
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GO Term
GO:0009113 | purine nucleobase biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
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GO Term
GO:0017150 | tRNA dihydrouridine synthase activity
Description: Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor.
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GO Term
GO:0006527 | arginine catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
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GO Term
GO:0008295 | spermidine biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
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GO Term
GO:0008792 | arginine decarboxylase activity
Description: Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2).
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GO Term
GO:0009415 | response to water
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.
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GO Term
GO:0004401 | histidinol-phosphatase activity
Description: Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate.
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GO Term
GO:0004146 | dihydrofolate reductase activity
Description: Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.
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GO Term
GO:0004799 | thymidylate synthase activity
Description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.
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GO Term
GO:0006231 | dTMP biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).
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GO Term
GO:0006545 | glycine biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.
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GO Term
GO:0048015 | phosphatidylinositol-mediated signaling
Description: A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
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GO Term
GO:0004930 | G protein-coupled receptor activity
Description: Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
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GO Term
GO:0008158 | hedgehog receptor activity
Description: Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.
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GO Term
GO:0004181 | metallocarboxypeptidase activity
Description: Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
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GO Term
GO:0070008 | serine-type exopeptidase activity
Description: Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
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GO Term
GO:0006596 | polyamine biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
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GO Term
GO:0006694 | steroid biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
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GO Term
GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity
Description: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
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GO Term
GO:0016298 | lipase activity
Description: Catalysis of the hydrolysis of a lipid or phospholipid.
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GO Term
GO:0004590 | orotidine-5'-phosphate decarboxylase activity
Description: Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.
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GO Term
GO:0005674 | transcription factor TFIIF complex
Description: A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.
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GO Term
GO:0035299 | inositol pentakisphosphate 2-kinase activity
Description: Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+).
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GO Term
GO:0000910 | cytokinesis
Description: The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
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GO Term
GO:0004585 | ornithine carbamoyltransferase activity
Description: Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
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GO Term
GO:0006591 | ornithine metabolic process
Description: The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
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GO Term
GO:0008725 | DNA-3-methyladenine glycosylase activity
Description: Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.
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GO Term
GO:0007155 | cell adhesion
Description: The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
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GO Term
GO:0009107 | lipoate biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.
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GO Term
GO:0016415 | octanoyltransferase activity
Description: Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule.
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GO Term
GO:0009512 | cytochrome b6f complex
Description: Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.
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GO Term
GO:0005615 | extracellular space
Description: That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
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GO Term
GO:0004852 | uroporphyrinogen-III synthase activity
Description: Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III.
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GO Term
GO:0010389 | regulation of G2/M transition of mitotic cell cycle
Description: Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
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GO Term
GO:0048193 | Golgi vesicle transport
Description: The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
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GO Term
GO:0004084 | branched-chain-amino-acid transaminase activity
Description: Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
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GO Term
GO:0009081 | branched-chain amino acid metabolic process
Description: The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
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GO Term
GO:0045739 | positive regulation of DNA repair
Description: Any process that activates or increases the frequency, rate or extent of DNA repair.
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GO Term
GO:0070531 | BRCA1-A complex
Description: A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.
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GO Term
GO:0070552 | BRISC complex
Description: A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.
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GO Term
GO:0004325 | ferrochelatase activity
Description: Catalysis of the reaction: protoheme = Fe(2+) + protoporphyrin IX.
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GO Term
GO:0006783 | heme biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
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GO Term
GO:0006672 | ceramide metabolic process
Description: The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
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GO Term
GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Description: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
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GO Term
GO:0004106 | chorismate mutase activity
Description: Catalysis of the reaction: chorismate = prephenate.
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GO Term
GO:0046417 | chorismate metabolic process
Description: The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid.
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GO Term
GO:0019538 | protein metabolic process
Description: The chemical reactions and pathways involving a protein. Includes protein modification.
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GO Term
GO:0004817 | cysteine-tRNA ligase activity
Description: Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
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GO Term
GO:0006423 | cysteinyl-tRNA aminoacylation
Description: The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
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GO Term
GO:0003968 | RNA-directed 5'-3' RNA polymerase activity
Description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
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GO Term
GO:0006811 | ion transport
Description: The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0005249 | voltage-gated potassium channel activity
Description: Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
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GO Term
GO:0003991 | acetylglutamate kinase activity
Description: Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate.
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GO Term
GO:0034508 | centromere complex assembly
Description: The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
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GO Term
GO:0070461 | SAGA-type complex
Description: A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins.
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GO Term
GO:0047134 | protein-disulfide reductase activity
Description: Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
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GO Term
GO:0012511 | monolayer-surrounded lipid storage body
Description: A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.
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GO Term
GO:0000917 | division septum assembly
Description: The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
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GO Term
GO:0009976 | tocopherol cyclase activity
Description: Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol).
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GO Term
GO:0004652 | polynucleotide adenylyltransferase activity
Description: Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
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GO Term
GO:0031123 | RNA 3'-end processing
Description: Any process involved in forming the mature 3' end of an RNA molecule.
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GO Term
GO:0043631 | RNA polyadenylation
Description: The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.
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GO Term
GO:0032957 | inositol trisphosphate metabolic process
Description: The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
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GO Term
GO:0047325 | inositol tetrakisphosphate 1-kinase activity
Description: Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.
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GO Term
GO:0052725 | inositol-1,3,4-trisphosphate 6-kinase activity
Description: Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+).
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GO Term
GO:0052726 | inositol-1,3,4-trisphosphate 5-kinase activity
Description: Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+).
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GO Term
GO:0005887 | integral component of plasma membrane
Description: The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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GO Term
GO:0008515 | sucrose transmembrane transporter activity
Description: Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.
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GO Term
GO:0015770 | sucrose transport
Description: The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.
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GO Term
GO:0004611 | phosphoenolpyruvate carboxykinase activity
Description: Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products.
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GO Term
GO:0004612 | phosphoenolpyruvate carboxykinase (ATP) activity
Description: Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate.
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GO Term
GO:0017076 | purine nucleotide binding
Description: Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.
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GO Term
GO:0004733 | pyridoxamine-phosphate oxidase activity
Description: Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide.
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GO Term
GO:0008615 | pyridoxine biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.
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GO Term
GO:0004056 | argininosuccinate lyase activity
Description: Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.
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GO Term
GO:0042450 | arginine biosynthetic process via ornithine
Description: The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.
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GO Term
GO:0004588 | orotate phosphoribosyltransferase activity
Description: Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.
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GO Term
GO:0006221 | pyrimidine nucleotide biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
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GO Term
GO:0044205 | 'de novo' UMP biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
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GO Term
GO:0004828 | serine-tRNA ligase activity
Description: Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).
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GO Term
GO:0006434 | seryl-tRNA aminoacylation
Description: The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA.
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GO Term
GO:0046148 | pigment biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.
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GO Term
GO:0016168 | chlorophyll binding
Description: Interacting selectively and non-covalently with chlorophyll; any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.
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GO Term
GO:0004619 | phosphoglycerate mutase activity
Description: Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate.
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GO Term
GO:0005544 | calcium-dependent phospholipid binding
Description: Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
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GO Term
GO:0070402 | NADPH binding
Description: Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
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GO Term
GO:0003951 | NAD+ kinase activity
Description: Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+).
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GO Term
GO:0004143 | diacylglycerol kinase activity
Description: Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.
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GO Term
GO:0007205 | protein kinase C-activating G protein-coupled receptor signaling pathway
Description: The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
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GO Term
GO:0003937 | IMP cyclohydrolase activity
Description: Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide.
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GO Term
GO:0004643 | phosphoribosylaminoimidazolecarboxamide formyltransferase activity
Description: Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide.
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