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Search results 301 to 400 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0030131 | clathrin adaptor complex
Description: A membrane coat adaptor complex that links clathrin to a membrane.
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GO Term
GO:0003872 | 6-phosphofructokinase activity
Description: Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.
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GO Term
GO:0005945 | 6-phosphofructokinase complex
Description: A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.
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GO Term
GO:0006002 | fructose 6-phosphate metabolic process
Description: The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.
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GO Term
GO:0006096 | glycolytic process
Description: The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
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GO Term
GO:0005085 | guanyl-nucleotide exchange factor activity
Description: Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
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GO Term
GO:0004089 | carbonate dehydratase activity
Description: Catalysis of the reaction: H2CO3 = CO2 + H2O.
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GO Term
GO:0015976 | carbon utilization
Description: A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.
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GO Term
GO:0006073 | cellular glucan metabolic process
Description: The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell.
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GO Term
GO:0016762 | xyloglucan:xyloglucosyl transferase activity
Description: Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.
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GO Term
GO:0043169 | cation binding
Description: Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.
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GO Term
GO:0015935 | small ribosomal subunit
Description: The smaller of the two subunits of a ribosome.
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GO Term
GO:0004349 | glutamate 5-kinase activity
Description: Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+).
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GO Term
GO:0006561 | proline biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
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GO Term
GO:0004350 | glutamate-5-semialdehyde dehydrogenase activity
Description: Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP(+) + phosphate = L-glutamyl 5-phosphate + H(+) + NADPH.
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GO Term
GO:0006621 | protein retention in ER lumen
Description: The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
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GO Term
GO:0046923 | ER retention sequence binding
Description: Interacting selectively and non-covalently with an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER.
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GO Term
GO:0048544 | recognition of pollen
Description: The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the recognition or rejection of the self pollen by cells in the stigma. This process ensures out-breeding in certain plant species.
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GO Term
GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity
Description: Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
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GO Term
GO:0007050 | cell cycle arrest
Description: A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
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GO Term
GO:0004592 | pantoate-beta-alanine ligase activity
Description: Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.
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GO Term
GO:0015940 | pantothenate biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
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GO Term
GO:0008375 | acetylglucosaminyltransferase activity
Description: Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar.
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GO Term
GO:0003755 | peptidyl-prolyl cis-trans isomerase activity
Description: Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
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GO Term
GO:0032549 | ribonucleoside binding
Description: Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.
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GO Term
GO:0008131 | primary amine oxidase activity
Description: Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
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GO Term
GO:0009308 | amine metabolic process
Description: The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
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GO Term
GO:0048038 | quinone binding
Description: Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.
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GO Term
GO:0003934 | GTP cyclohydrolase I activity
Description: Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
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GO Term
GO:0046654 | tetrahydrofolate biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
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GO Term
GO:0016887 | ATPase activity
Description: Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
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GO Term
GO:0042626 | ATPase-coupled transmembrane transporter activity
Description: Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
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GO Term
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors
Description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
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GO Term
GO:0030259 | lipid glycosylation
Description: Covalent attachment of a glycosyl residue to a lipid molecule.
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GO Term
GO:0007005 | mitochondrion organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
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GO Term
GO:0004372 | glycine hydroxymethyltransferase activity
Description: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
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GO Term
GO:0006544 | glycine metabolic process
Description: The chemical reactions and pathways involving glycine, aminoethanoic acid.
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GO Term
GO:0006563 | L-serine metabolic process
Description: The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
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GO Term
GO:0008173 | RNA methyltransferase activity
Description: Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
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GO Term
GO:0005200 | structural constituent of cytoskeleton
Description: The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
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GO Term
GO:0008272 | sulfate transport
Description: The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0015116 | sulfate transmembrane transporter activity
Description: Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
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GO Term
GO:0008242 | omega peptidase activity
Description: Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by isopeptide bonds (peptide linkages other than those of alpha-carboxyl to alpha-amino groups).
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GO Term
GO:0006952 | defense response
Description: Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
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GO Term
GO:0043531 | ADP binding
Description: Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate.
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GO Term
GO:0006857 | oligopeptide transport
Description: The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
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GO Term
GO:0005198 | structural molecule activity
Description: The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
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GO Term
GO:0030130 | clathrin coat of trans-Golgi network vesicle
Description: A clathrin coat found on a vesicle of the trans-Golgi network.
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GO Term
GO:0030132 | clathrin coat of coated pit
Description: The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.
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GO Term
GO:0000439 | transcription factor TFIIH core complex
Description: The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.
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GO Term
GO:0016868 | intramolecular transferase activity, phosphotransferases
Description: Catalysis of the transfer of a phosphate group from one position to another within a single molecule.
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GO Term
GO:0003885 | D-arabinono-1,4-lactone oxidase activity
Description: Catalysis of the reaction: D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2) + H(+).
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GO Term
GO:0030976 | thiamine pyrophosphate binding
Description: Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
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GO Term
GO:0004177 | aminopeptidase activity
Description: Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
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GO Term
GO:0008235 | metalloexopeptidase activity
Description: Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
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GO Term
GO:0003876 | AMP deaminase activity
Description: Catalysis of the reaction: AMP + H2O = IMP + NH3.
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GO Term
GO:0006188 | IMP biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate.
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GO Term
GO:0019239 | deaminase activity
Description: Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3).
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GO Term
GO:0008430 | selenium binding
Description: Interacting selectively and non-covalently with selenium (Se).
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GO Term
GO:0045454 | cell redox homeostasis
Description: Any process that maintains the redox environment of a cell or compartment within a cell.
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GO Term
GO:0051087 | chaperone binding
Description: Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
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GO Term
GO:0006826 | iron ion transport
Description: The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0006879 | cellular iron ion homeostasis
Description: Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
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GO Term
GO:0008199 | ferric iron binding
Description: Interacting selectively and non-covalently with ferric iron, Fe(III).
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GO Term
GO:0008271 | secondary active sulfate transmembrane transporter activity
Description: Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
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GO Term
GO:0005856 | cytoskeleton
Description: Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
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GO Term
GO:0008483 | transaminase activity
Description: Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.
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GO Term
GO:0006979 | response to oxidative stress
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
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GO Term
GO:0005764 | lysosome
Description: A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
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GO Term
GO:0006665 | sphingolipid metabolic process
Description: The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
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GO Term
GO:0006855 | drug transmembrane transport
Description: The process in which a drug is transported across a membrane.
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GO Term
GO:0015297 | antiporter activity
Description: Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
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GO Term
GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity
Description: Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
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GO Term
GO:0019901 | protein kinase binding
Description: Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
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GO Term
GO:0004659 | prenyltransferase activity
Description: Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).
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GO Term
GO:0032934 | sterol binding
Description: Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.
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GO Term
GO:0003913 | DNA photolyase activity
Description: Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA.
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GO Term
GO:0000175 | 3'-5'-exoribonuclease activity
Description: Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
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GO Term
GO:0005801 | cis-Golgi network
Description: The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
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GO Term
GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport
Description: The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
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GO Term
GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
Description: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
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GO Term
GO:0004222 | metalloendopeptidase activity
Description: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
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GO Term
GO:0008276 | protein methyltransferase activity
Description: Catalysis of the transfer of a methyl group (CH3-) to a protein.
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GO Term
GO:0032259 | methylation
Description: The process in which a methyl group is covalently attached to a molecule.
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GO Term
GO:0004802 | transketolase activity
Description: Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor.
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GO Term
GO:0003866 | 3-phosphoshikimate 1-carboxyvinyltransferase activity
Description: Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.
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GO Term
GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups
Description: Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
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GO Term
GO:0000145 | exocyst
Description: A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.
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GO Term
GO:0006887 | exocytosis
Description: A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
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GO Term
GO:0006904 | vesicle docking involved in exocytosis
Description: The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.
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GO Term
GO:0006303 | double-strand break repair via nonhomologous end joining
Description: The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
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GO Term
GO:0016817 | hydrolase activity, acting on acid anhydrides
Description: Catalysis of the hydrolysis of any acid anhydride.
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GO Term
GO:0005086 | ARF guanyl-nucleotide exchange factor activity
Description: Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
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GO Term
GO:0032012 | regulation of ARF protein signal transduction
Description: Any process that modulates the frequency, rate or extent of ARF protein signal transduction.
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GO Term
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Description: Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
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GO Term
GO:0003746 | translation elongation factor activity
Description: Functions in chain elongation during polypeptide synthesis at the ribosome.
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GO Term
GO:0004462 | lactoylglutathione lyase activity
Description: Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
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GO Term
GO:0006913 | nucleocytoplasmic transport
Description: The directed movement of molecules between the nucleus and the cytoplasm.
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GO Term
GO:0004722 | protein serine/threonine phosphatase activity
Description: Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
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GO Term
GO:0046577 | long-chain-alcohol oxidase activity
Description: Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.
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