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Search results 4201 to 4300 out of 44733 for *

Category restricted to GOTerm (x)

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Category: GOTerm
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Type Details Score
GO Term
GO:0046629 | gamma-delta T cell activation
Description: The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
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GO Term
GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
Description: The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.
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GO Term
GO:0002292 | T cell differentiation involved in immune response
Description: The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
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GO Term
GO:0002293 | alpha-beta T cell differentiation involved in immune response
Description: The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
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GO Term
GO:0002294 | CD4-positive, alpha-beta T cell differentiation involved in immune response
Description: The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
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GO Term
GO:0043367 | CD4-positive, alpha-beta T cell differentiation
Description: The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.
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GO Term
GO:0035710 | CD4-positive, alpha-beta T cell activation
Description: The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
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GO Term
GO:0042093 | T-helper cell differentiation
Description: The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.
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GO Term
GO:0002295 | T-helper cell lineage commitment
Description: The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.
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GO Term
GO:0043373 | CD4-positive, alpha-beta T cell lineage commitment
Description: The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.
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GO Term
GO:0043369 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
Description: The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.
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GO Term
GO:0045058 | T cell selection
Description: The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.
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GO Term
GO:0043368 | positive T cell selection
Description: The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.
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GO Term
GO:0002360 | T cell lineage commitment
Description: The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.
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GO Term
GO:0002363 | alpha-beta T cell lineage commitment
Description: The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell.
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GO Term
GO:0002296 | T-helper 1 cell lineage commitment
Description: The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.
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GO Term
GO:0045063 | T-helper 1 cell differentiation
Description: The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
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GO Term
GO:0042088 | T-helper 1 type immune response
Description: An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.
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GO Term
GO:0002297 | T-helper 2 cell lineage commitment
Description: The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.
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GO Term
GO:0045064 | T-helper 2 cell differentiation
Description: The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4.
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GO Term
GO:0042092 | type 2 immune response
Description: An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
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GO Term
GO:0002298 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
Description: The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.
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GO Term
GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
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GO Term
GO:0045066 | regulatory T cell differentiation
Description: The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types.
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GO Term
GO:0002299 | alpha-beta intraepithelial T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
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GO Term
GO:0002300 | CD8-positive, alpha-beta intraepithelial T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
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GO Term
GO:0043374 | CD8-positive, alpha-beta T cell differentiation
Description: The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.
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GO Term
GO:0036037 | CD8-positive, alpha-beta T cell activation
Description: The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
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GO Term
GO:0002301 | CD4-positive, alpha-beta intraepithelial T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
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GO Term
GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response
Description: The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
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GO Term
GO:0042492 | gamma-delta T cell differentiation
Description: The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.
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GO Term
GO:0002303 | gamma-delta T cell differentiation involved in immune response
Description: The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
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GO Term
GO:0002304 | gamma-delta intraepithelial T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
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GO Term
GO:0002305 | CD8-positive, gamma-delta intraepithelial T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
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GO Term
GO:0002306 | CD4-positive gamma-delta intraepithelial T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
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GO Term
GO:0002307 | CD8-positive, alpha-beta regulatory T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.
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GO Term
GO:0045065 | cytotoxic T cell differentiation
Description: The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.
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GO Term
GO:0002308 | CD8-positive, alpha-beta cytotoxic T cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
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GO Term
GO:0046630 | gamma-delta T cell proliferation
Description: The expansion of a gamma-delta T cell population by cell division.
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GO Term
GO:0002311 | gamma-delta T cell proliferation involved in immune response
Description: The expansion of a gamma-delta T cell population by cell division as part of an immune response.
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GO Term
GO:0002313 | mature B cell differentiation involved in immune response
Description: The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response.
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GO Term
GO:0002314 | germinal center B cell differentiation
Description: The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).
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GO Term
GO:0002315 | marginal zone B cell differentiation
Description: The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL).
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GO Term
GO:0002316 | follicular B cell differentiation
Description: The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
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GO Term
GO:0002317 | plasma cell differentiation
Description: The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.
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GO Term
GO:0002318 | myeloid progenitor cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
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GO Term
GO:0002319 | memory B cell differentiation
Description: The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.
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GO Term
GO:0090715 | immunological memory formation process
Description: Any immunological memory process that can contribute to the formation of immunological memory.
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GO Term
GO:0090713 | immunological memory process
Description: Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory.
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GO Term
GO:0002320 | lymphoid progenitor cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.
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GO Term
GO:0002321 | natural killer cell progenitor differentiation
Description: The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor.
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GO Term
GO:0002323 | natural killer cell activation involved in immune response
Description: The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
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GO Term
GO:0002324 | natural killer cell proliferation involved in immune response
Description: The expansion of a natural killer cell population by cell division as part of an immune response.
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GO Term
GO:0002325 | natural killer cell differentiation involved in immune response
Description: The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response.
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GO Term
GO:0002326 | B cell lineage commitment
Description: The process in which a lymphoid progenitor cell becomes committed to become any type of B cell.
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GO Term
GO:0002327 | immature B cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of an immature B cell.
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GO Term
GO:0002328 | pro-B cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
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GO Term
GO:0002329 | pre-B cell differentiation
Description: The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
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GO Term
GO:0002330 | pre-B cell receptor expression
Description: The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, including expression of the surrogate light chain, association of the surrogate light chain with heavy chain, and expression of the complete pre-B cell receptor on the cell surface.
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GO Term
GO:0002331 | pre-B cell allelic exclusion
Description: Expression of a single heavy chain allele during pre-B cell differentiation.
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GO Term
GO:0002332 | transitional stage B cell differentiation
Description: The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.
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GO Term
GO:0002333 | transitional one stage B cell differentiation
Description: The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21.
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GO Term
GO:0002334 | transitional two stage B cell differentiation
Description: The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.
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GO Term
GO:0002336 | B-1 B cell lineage commitment
Description: The process in which an immature B cell becomes committed to become a B-1 B cell.
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GO Term
GO:0002337 | B-1a B cell differentiation
Description: The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.
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GO Term
GO:0002338 | B-1b B cell differentiation
Description: The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
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GO Term
GO:0002340 | central B cell selection
Description: Any B cell selection process that occurs in the bone marrow.
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GO Term
GO:0002510 | central B cell tolerance induction
Description: Tolerance induction of B cells in the bone marrow.
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GO Term
GO:0002341 | central B cell anergy
Description: Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.
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GO Term
GO:0002515 | B cell anergy
Description: Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.
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GO Term
GO:0002514 | B cell tolerance induction
Description: A process involving any mechanism for tolerance induction in B cells.
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GO Term
GO:0002508 | central tolerance induction
Description: Tolerance induction in the central lymphoid organs: the thymus and bone marrow.
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GO Term
GO:0002342 | central B cell deletion
Description: The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.
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GO Term
GO:0002516 | B cell deletion
Description: The apoptotic death of B cells which is part of B cell tolerance induction.
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GO Term
GO:1902742 | apoptotic process involved in development
Description: Any apoptotic process that is involved in anatomical structure development.
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GO Term
GO:0002452 | B cell receptor editing
Description: The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.
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GO Term
GO:0002345 | peripheral B cell receptor editing
Description: The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation.
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GO Term
GO:0002346 | B cell positive selection
Description: Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor.
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GO Term
GO:0002347 | response to tumor cell
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.
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GO Term
GO:0002348 | central B cell positive selection
Description: Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.
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GO Term
GO:0002349 | histamine production involved in inflammatory response
Description: The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
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GO Term
GO:0002350 | peripheral B cell positive selection
Description: Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.
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GO Term
GO:0002351 | serotonin production involved in inflammatory response
Description: The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
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GO Term
GO:0002352 | B cell negative selection
Description: Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.
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GO Term
GO:0002353 | plasma kallikrein-kinin cascade
Description: A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.
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GO Term
GO:0002354 | central B cell negative selection
Description: Any process leading to negative selection of B cells in the bone marrow.
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GO Term
GO:0002355 | detection of tumor cell
Description: The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal.
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GO Term
GO:0002356 | peripheral B cell negative selection
Description: Any process leading to negative selection of B cells in the periphery.
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GO Term
GO:0002357 | defense response to tumor cell
Description: Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism.
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GO Term
GO:0002358 | B cell homeostatic proliferation
Description: The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.
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GO Term
GO:0002359 | B-1 B cell proliferation
Description: The expansion of a B-1 B cell by cell division. Follows B cell activation.
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GO Term
GO:0002362 | CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment
Description: The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
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GO Term
GO:0002364 | NK T cell lineage commitment
Description: The process in which a pro-T cell becomes committed to becoming an NK T cell.
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GO Term
GO:0002365 | gamma-delta T cell lineage commitment
Description: The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell.
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GO Term
GO:0002367 | cytokine production involved in immune response
Description: The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.
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GO Term
GO:0002368 | B cell cytokine production
Description: Any process that contributes to cytokine production by a B cell.
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GO Term
GO:0002369 | T cell cytokine production
Description: Any process that contributes to cytokine production by a T cell.
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GO Term
GO:0002370 | natural killer cell cytokine production
Description: Any process that contributes to cytokine production by a natural killer cell.
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GO Term
GO:0002371 | dendritic cell cytokine production
Description: Any process that contributes to cytokine production by a dendritic cell.
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GO Term
GO:0002372 | myeloid dendritic cell cytokine production
Description: Any process that contributes to cytokine production by a myeloid dendritic cell.
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