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Search results 44401 to 44500 out of 44733 for *

Category restricted to GOTerm (x)

0.039s

Categories

Category: GOTerm
Type Details Score
GO Term
Description: The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.
GO Term
Description: Any process that activates or increases the frequency, rate or extent of axonogenesis.
GO Term
Description: Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
GO Term
Description: The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.
GO Term
Description: Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
GO Term
Description: The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GO Term
Description: The chemical reactions and pathways involving quinone.
GO Term
Description: The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
GO Term
Description: The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.
GO Term
Description: The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
GO Term
Description: Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.
GO Term
Description: Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.
GO Term
Description: A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
GO Term
Description: A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.
GO Term
Description: A cascade of processes induced by the detection of DNA damage within a cell.
GO Term
Description: A mitotic cell cycle checkpoint that detects and negatively regulates progression through the cell cycle in response to DNA damage.
GO Term
Description: Any process in which is the spindle is transported to, and/or maintained in, a specific location.
GO Term
Description: The directed movement of the spindle to a specific location in the cell.
GO Term
Description: Interacting selectively and non-covalently with a dopamine receptor.
GO Term
Description: The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.
GO Term
Description: The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.
GO Term
Description: The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
GO Term
Description: The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
GO Term
Description: Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GO Term
Description: Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
GO Term
Description: The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
GO Term
Description: Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.
GO Term
Description: Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.
GO Term
Description: Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.
GO Term
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.
GO Term
Description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
GO Term
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.
GO Term
Description: A DNA recombination process that results in the equal exchange of genetic material between the recombining DNA molecules.
GO Term
Description: The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
GO Term
Description: A synapse that uses glutamate as a neurotransmitter.
GO Term
Description: An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.
GO Term
Description: Any process that modulates the frequency, rate or extent of receptor signaling via STAT.
GO Term
Description: Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT.
GO Term
Description: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
GO Term
Description: Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GO Term
Description: The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO Term
Description: The adhesion of one platelet to one or more other platelets via adhesion molecules.
GO Term
Description: The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.
GO Term
Description: The attachment of a cell to a second cell of the identical type via adhesion molecules.
GO Term
Description: A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
GO Term
Description: Any process that modulates the levels of body fluids.
GO Term
Description: A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
GO Term
Description: A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.
GO Term
Description: The directed movement of lipids within cells.
GO Term
Description: The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.
GO Term
Description: Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO Term
Description: The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
GO Term
Description: The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.
GO Term
Description: The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.
GO Term
Description: The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
GO Term
Description: The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
GO Term
Description: Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO Term
Description: A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5.
GO Term
Description: Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA.
GO Term
Description: The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products.
GO Term
Description: The transport of substances that occurs outside cells.
GO Term
Description: The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
GO Term
Description: A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules.
GO Term
Description: A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
GO Term
Description: Any process that modulates the frequency, rate or extent of hemopoiesis.
GO Term
Description: The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.
GO Term
Description: Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
GO Term
Description: The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
GO Term
Description: The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.
GO Term
Description: Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO Term
Description: The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.
GO Term
Description: The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
GO Term
Description: A protein complex which is capable of ATPase activity.
GO Term
Description: A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.
GO Term
Description: A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).
GO Term
Description: A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.
GO Term
Description: A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
GO Term
Description: Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
GO Term
Description: The directed movement of synaptic vesicles.
GO Term
Description: A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair.
GO Term
Description: Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
GO Term
Description: Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.
GO Term
Description: The portion of the nuclear lumen proximal to the inner nuclear membrane.
GO Term
Description: Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
GO Term
Description: The directed movement of the nucleus to a specific location within a cell.
GO Term
Description: The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle.
GO Term
Description: Any process that modulates the frequency, rate or extent of Ras protein signal transduction.
GO Term
Description: Interacting selectively and non-covalently with a mitogen-activated protein kinase.
GO Term
Description: The portion of the plasma membrane surrounding the leading edge of a motile cell.
GO Term
Description: The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.
GO Term
Description: The area of a motile cell closest to the direction of movement.
GO Term
Description: The directed movement of a protein to a specific location in a chloroplast.
GO Term
Description: A process in which a protein is transported to, or maintained at, a location in a chloroplast.
GO Term
Description: The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
GO Term
Description: Cleavage of the 5'-cap of an RNA.
GO Term
Description: The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
GO Term
Description: A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.
GO Term
Description: Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.
GO Term
Description: The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.
GO Term
Description: The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
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