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Search results 1801 to 1900 out of 202262 for *

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Categories

Category: OntologyTerm
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Type Details Score
Ontology Term
PANTHER:PTHR10067 | PHOSPHATIDYLSERINE DECARBOXYLASE
 
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Ontology Term
Pfam:PF02666 | Phosphatidylserine decarboxylase
Description: This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyse the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine [2].
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Ontology Term
PANTHER:PTHR10520 | TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED
 
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Ontology Term
PANTHER:PTHR10520:SF7 | FORMYL TRANSFERASE-RELATED
 
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Ontology Term
Pfam:PF08264 | Anticodon-binding domain of tRNA ligase
Description: This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
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Ontology Term
PANTHER:PTHR23249 | TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT
 
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Ontology Term
Pfam:PF04099 | Sybindin-like family
Description: Sybindin is a physiological syndecan-2 ligand on dendritic spines, the small protrusions on the surface of dendrites that receive the vast majority of excitatory synapses [1].
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Ontology Term
Pfam:PF05641 | Agenet domain
Description: This domain is related to the TUDOR domain Pfam:PF00567 [1]. The function of the agenet domain is unknown. This family now matches both the two Agenet domains in the FMR proteins [1].
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Ontology Term
PANTHER:PTHR31818 | O-FUCOSYLTRANSFERASE 16
 
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Ontology Term
PANTHER:PTHR31818:SF0 | SUBFAMILY NOT NAMED
 
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Ontology Term
PANTHER:PTHR13402 | RGPR-RELATED
 
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Ontology Term
Pfam:PF12931 | Sec23-binding domain of Sec16
Description: Sec16 is a multi-domain vesicle coat protein. The C-terminal region is the part that binds to Sec23, a COPII vesicle coat protein. This association is part of the transport vesicle coat structure [1].
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Ontology Term
Pfam:PF12932 | Vesicle coat trafficking protein Sec16 mid-region
Description: Sec16 is a multi-domain vesicle coat protein. This central region is the functional part of the molecules and thus is vital for the family's role in mediating the movement of protein-cargo between the organelles of the secretory pathway [1].
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Ontology Term
PANTHER:PTHR31321 | ACYL-COA THIOESTER HYDROLASE YBHC-RELATED
 
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Ontology Term
Pfam:PF11875 | DnaJ-like protein C11, C-terminal
Description: This is the C-terminal domain found in DnaJ-like proteins, including DnaJ homolog subfamily C member 11 (DNAJC11) from mammals and Chaperone protein dnaJ 13 from Arabidopsis. DNAJC11 is a mitochondrial outer membrane protein involved in mitochondrial biogenesis and in the response to microenvironment changes and requirements. The J-domain is mediated its mitochondrial localization, while this domain is critical for protein-protein interactions [1].
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Ontology Term
PANTHER:PTHR10969 | MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED
 
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Ontology Term
Pfam:PF02991 | Autophagy protein Atg8 ubiquitin like
Description: Light chain 3 is proposed to function primarily as a subunit of microtubule associated proteins 1A and 1B and that its expression may regulate microtubule binding activity [1]. Autophagy is generally known as a process involved in the degradation of bulk cytoplasmic components that are non-specifically sequestered into an autophagosome, where they are sequestered into double-membrane vesicles and delivered to the degradative organelle, the lysosome/vacuole, for breakdown and eventual recycling of the resulting macromolecules. The yeast proteins are involved in the autophagosome, and Atg8 binds Atg19, via its N-terminus and the C-terminus of Atg19.
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Ontology Term
PANTHER:PTHR11540:SF3 | SUBFAMILY NOT NAMED
 
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Ontology Term
Pfam:PF15413 | Pleckstrin homology domain
Description: This Pleckstrin homology domain is found in some fungal species.
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Ontology Term
PANTHER:PTHR31681 | C2H2-LIKE ZINC FINGER PROTEIN
 
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Ontology Term
PANTHER:PTHR11776 | ADENINE PHOSPHORIBOSYLTRANSFERASE
 
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Ontology Term
PANTHER:PTHR11776:SF0 | ADENINE PHOSPHORIBOSYLTRANSFERASE 1, CHLOROPLASTIC
 
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Ontology Term
Pfam:PF00156 | Phosphoribosyl transferase domain
Description: This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7, Swiss:P07672. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase Swiss:P51900. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8 Swiss:P36766. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1 Swiss:P09329. Amidophosphoribosyltransferase EC:2.4.2.14 Swiss:P00496. Orotate phosphoribosyl-transferase EC:2.4.2.10 Swiss:P11172. Uracil phosphoribosyl-transferase EC:2.4.2.9 Swiss:P25532. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22 Swiss:P00501. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain [1].
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Ontology Term
PANTHER:PTHR23023 | DIMETHYLANILINE MONOOXYGENASE
 
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Ontology Term
PANTHER:PTHR23023:SF4 | DIMETHYLANALINE MONOOXYGENASE-LIKE
 
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Ontology Term
Pfam:PF00743 | Flavin-binding monooxygenase-like
Description: This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.
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Ontology Term
Pfam:PF04640 | PLATZ transcription factor
Description: Plant AT-rich sequence and zinc-binding proteins (PLATZ) are zinc dependant DNA binding proteins. They bind to AT rich sequences and functions in transcriptional repression [1]. Included in this family is the protein RGF1 INDUCIBLE TRANSCRIPTION FACTOR 1 (RITF1), a transcription factor that plays a central role in mediating RGF1 hormone peptide signalling, leading to the production of reactive oxygen species (ROS) in roots to modulate meristem size and root growth, probably via oxidative post-translational modification of the transcription factor PLETHORA [2].
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Ontology Term
PANTHER:PTHR31953 | BETA-FRUCTOFURANOSIDASE, INSOLUBLE ISOENZYME CWINV1-RELATED
 
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Ontology Term
Pfam:PF00251 | Glycosyl hydrolases family 32 N-terminal domain
Description: This domain corresponds to the N-terminal domain of glycosyl hydrolase family 32 which forms a five bladed beta propeller structure [1].
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Ontology Term
Pfam:PF08244 | Glycosyl hydrolases family 32 C terminal
Description: This domain corresponds to the C terminal domain of glycosyl hydrolase family 32. It forms a beta sandwich module [1].
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Ontology Term
Pfam:PF11837 | Beta-fructofuranosidase, N-terminal domain
Description: This entry represents the N-terminal domain of beta-fructofuranosidase, which is involved in the hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides [1].
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Ontology Term
Pfam:PF00805 | Pentapeptide repeats (8 copies)
Description: These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK [1]. The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix [2]. The repeat can be approximately described as A(D/N)LXX, where X can be any amino acid.
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Ontology Term
PANTHER:PTHR31989 | NAC DOMAIN-CONTAINING PROTEIN 82-RELATED
 
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Ontology Term
Pfam:PF02365 | No apical meristem (NAM) protein
Description: This is a family of no apical meristem (NAM) proteins these are plant development proteins. Mutations in NAM result in the failure to develop a shoot apical meristem in petunia embryos [2]. NAM is indicated as having a role in determining positions of meristems and primordial [2]. One member of this family NAP (NAC-like, activated by AP3/PI) is encoded by the target genes of the AP3/PI transcriptional activators and functions in the transition between growth by cell division and cell expansion in stamens and petals [1].
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Ontology Term
Pfam:PF13405 | EF-hand domain
Description: NULL
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Ontology Term
PANTHER:PTHR22602 | UNCHARACTERIZED
 
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Ontology Term
PANTHER:PTHR22602:SF0 | TRANSFERASE CAF17, MITOCHONDRIAL-RELATED
 
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Ontology Term
Pfam:PF01571 | Aminomethyltransferase folate-binding domain
Description: This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyses the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
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Ontology Term
Pfam:PF08669 | Glycine cleavage T-protein C-terminal barrel domain
Description: This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyses the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
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Ontology Term
Pfam:PF07279 | Protein of unknown function (DUF1442)
Description: This family consists of several hypothetical Arabidopsis thaliana proteins of around 225 residues in length. The function of this family is unknown.
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Ontology Term
PANTHER:PTHR10211 | DEOXYRIBODIPYRIMIDINE PHOTOLYASE
 
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Ontology Term
PANTHER:PTHR10211:SF0 | DNA PHOTOLYASE
 
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Ontology Term
PANTHER:PTHR12290 | CORNICHON-RELATED
 
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Ontology Term
Pfam:PF03311 | Cornichon protein
Description: NULL
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Ontology Term
PANTHER:PTHR11638 | ATP-DEPENDENT CLP PROTEASE
 
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Ontology Term
PANTHER:PTHR10361 | SODIUM-BILE ACID COTRANSPORTER
 
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Ontology Term
Pfam:PF01758 | Sodium Bile acid symporter family
Description: This family consists of Na+/bile acid co-transporters. These transmembrane proteins function in the liver in the uptake of bile acids from portal blood plasma a process mediated by the co-transport of Na+ [2]. Also in the family is ARC3 from S. cerevisiae Swiss:Q06598 this is a putative transmembrane protein involved in resistance to arsenic compounds [1].
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Ontology Term
Pfam:PF12214 | Cell cycle regulated microtubule associated protein
Description: This domain is found in eukaryotes. This domain is typically between 127 to 182 amino acids in length. This domain is found associated with Pfam:PF06886. This domain is found in the protein TPX2 (a.k.a p100) which is involved in cell cycling. It is only expressed between the start of the S phase and completion of cytokinesis. The microtubule-associated protein TPX2 has been reported to be crucial for mitotic spindle formation. This domain is close to the C terminal of TPX2. The protein importin alpha regulates the activity of TPX2 by binding to the nuclear localisation signal in this domain.
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Ontology Term
Pfam:PF02225 | PA domain
Description: The PA (Protease associated) domain is found as an insert domain in diverse proteases. The PA domain is also found in a plant vacuolar sorting receptor Swiss:O22925 and members of the RZF family Swiss:O43567. It has been suggested that this domain forms a lid-like structure that covers the active site in active proteases, and is involved in protein recognition in vacuolar sorting receptors [1].
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Ontology Term
PANTHER:PTHR31032 | PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC
 
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Ontology Term
PANTHER:PTHR31750 | PROTEIN STAY-GREEN 1, CHLOROPLASTIC-RELATED
 
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Ontology Term
Pfam:PF12638 | Staygreen protein
Description: This family of proteins have been implicated in chlorophyll degradation [1,2]. Intriguingly members of this family are also found in non-photosynthetic bacteria.
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Ontology Term
PANTHER:PTHR18063 | NF-E2 INDUCIBLE PROTEIN
 
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Ontology Term
PANTHER:PTHR18063:SF6 | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE
 
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Ontology Term
Pfam:PF04424 | MINDY deubiquitinase
Description: This entry represents a group of deubiquitinating (DUB) enzymes known as the MINDY family (MIU-containing novel DUB). Ubiquitin (Ub) is released one molecule at a time from the distal end of proteins with Lys48-linked polyubiquitin chains. Long polyubiquitin chains are preferred. The catalytic Cys and His residues have been identified by site-directed mutagenesis, as has the Gln that participates in formation of the oxyanion hole during catalysis. Despite the structural similarity to papain-like cysteine peptidases, a residue corresponding to the Asn that orientates the imidazolium ring of the catalytic His has not been identified. Members of the MINDY family of DUBs contain an MIU (motif interacting with Ub) motif, which is a helical motif that binds mono-Ub [1].
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Ontology Term
PANTHER:PTHR18896:SF15 | PHOSPHOLIPASE D BETA 1-RELATED
 
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Ontology Term
PANTHER:PTHR11877 | HYDROXYMETHYLGLUTARYL-COA SYNTHASE
 
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Ontology Term
PANTHER:PTHR11877:SF10 | TYPE III POLYKETIDE SYNTHASE B
 
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Ontology Term
Pfam:PF01154 | Hydroxymethylglutaryl-coenzyme A synthase N terminal
Description: NULL
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Ontology Term
Pfam:PF08540 | Hydroxymethylglutaryl-coenzyme A synthase C terminal
Description: NULL
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Ontology Term
PANTHER:PTHR14237 | MOLYBDOPTERIN COFACTOR SULFURASE MOSC
 
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Ontology Term
PANTHER:PTHR14237:SF3 | PROTEIN F56A11.5
 
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Ontology Term
Pfam:PF11523 | Protein of unknown function (DUF3223)
Description: This family of proteins has no known function.
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Ontology Term
PANTHER:PTHR13118 | NUCLEOPORIN 50
 
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Ontology Term
PANTHER:PTHR31839 | DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 1D
 
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Ontology Term
PANTHER:PTHR31839:SF0 | DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 1A-RELATED
 
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Ontology Term
PANTHER:PTHR13522 | UNCHARACTERIZED
 
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Ontology Term
PANTHER:PTHR13522:SF3 | U6 SNRNA PHOSPHODIESTERASE
 
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Ontology Term
Pfam:PF09749 | Uncharacterised conserved protein
Description: This entry is of proteins of approximately 300 residues conserved from plants to humans. It contains two conserved motifs, HxSL and FHVSL. The function is unknown.
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Ontology Term
PANTHER:PTHR12558 | CELL DIVISION CYCLE 16,23,27
 
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Ontology Term
PANTHER:PTHR12558:SF10 | CELL DIVISION CYCLE PROTEIN 23 HOMOLOG
 
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Ontology Term
Pfam:PF04049 | Anaphase promoting complex subunit 8 / Cdc23
Description: The anaphase-promoting complex is composed of eight protein subunits, including BimE (APC1), CDC27 (APC3), CDC16 (APC6), and CDC23 (APC8).
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Ontology Term
Pfam:PF13424 | Tetratricopeptide repeat
Description: NULL
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Ontology Term
PANTHER:PTHR24286:SF11 | CYTOCHROME P450, FAMILY 87, SUBFAMILY A, POLYPEPTIDE 2
 
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Ontology Term
PANTHER:PTHR31764 | PROTEIN HAPLESS 2
 
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Ontology Term
PANTHER:PTHR12716 | TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT
 
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Ontology Term
PANTHER:PTHR12716:SF8 | TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA
 
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Ontology Term
Pfam:PF02186 | TFIIE beta subunit core domain
Description: General transcription factor TFIIE consists of two subunits, TFIIE alpha Pfam:PF02002 and TFIIE beta. TFIIE beta has been found to bind to the region where the promoter starts to open to be single-stranded upon transcription initiation by RNA polymerase II. The structure of the DNA binding core region has been solved [1] and has a winged helix fold.
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Ontology Term
Pfam:PF10358 | N-terminal C2 in EEIG1 and EHBP1 proteins
Description: This version of the C2 domain was initally identified in the vertebrate estrogen early-induced gene 1 (EEIG1) [1], and its Drosophila ortholog required for uptake of dsRNA via the endocytotic machinery to induce RNAi silencing [2]. It is also in C.elegans ortholog Sym-3 (SYnthetic lethal with Mec-3) and the mammalian protein EHBP1 (EH domain Binding Protein-1) that regulates endocytotic recycling and two plant proteins, RPG that regulates Rhizobium-directed polar growth and PMI1 (Plastid Movement Impaired 1) that is essential for intracellular movement of chloroplasts in response to blue light [2].
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Ontology Term
PANTHER:PTHR10233:SF6 | METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE
 
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Ontology Term
Pfam:PF04525 | LURP-one-related
Description: The structure of this family has been solved. It comprises a 12-stranded beta barrel with a central C-terminal alpha helix. This helix is thought to be a transmembrane helix. It is structurally similar to the C-terminal domain of the Tubby protein [1]. In plants it plays a role in defense against pathogens [2].
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Ontology Term
PANTHER:PTHR21686 | UNCHARACTERIZED
 
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Ontology Term
Pfam:PF08698 | Fcf2 pre-rRNA processing
Description: This is a family of eukaryotic nucleolar proteins that are involved in pre-rRNA processing [1].
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Ontology Term
PANTHER:PTHR12203 | KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED
 
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Ontology Term
Pfam:PF05686 | Glycosyl transferase family 90
Description: This family of glycosyl transferases are specifically (mannosyl) glucuronoxylomannan/galactoxylomannan -beta 1,2-xylosyltransferases, EC:2.4.2.-.
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Ontology Term
PANTHER:PTHR11913 | COFILIN-RELATED
 
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Ontology Term
Pfam:PF00241 | Cofilin/tropomyosin-type actin-binding protein
Description: Severs actin filaments and binds to actin monomers.
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Ontology Term
Pfam:PF03652 | Holliday junction resolvase
Description: The central intermediate formed during mitotic and meiotic recombination is a four stranded DNA structure, also known as the Holliday junction (HJ), and its efficient resolution is essential for proper segregation of chromosomes. Resolution of HJs is mediated by a diverse group of DNA structure specific endonucleases known as Holliday junction resolvases (HJR) [1]. This entry is specific for RuvX also known as YqgF a family of nucleases which resolves the Holliday junction intermediates in genetic recombination[2-3]. Studies carried out in M. tuberculosis, have shown that YqgF/RuvX is a genuine HJR analogous to RuvC from E. coli. Furthermore, a single cysteine present in M. tuberculosis RuvX was found to be required for disulfide-bond mediated intermolecular dimerization and HJ resolution activity, suggesting that M. tuberculosis RuvX has adapted its YqgF protein to function like a typical RuvC family HJR [1].
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Ontology Term
PANTHER:PTHR11592 | GLUTATHIONE PEROXIDASE
 
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Ontology Term
Pfam:PF00255 | Glutathione peroxidase
Description: NULL
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Ontology Term
PANTHER:PTHR10024 | SYNAPTOTAGMIN
 
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Ontology Term
PANTHER:PTHR10024:SF97 | SYNAPTOTAGMIN-7
 
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Ontology Term
Pfam:PF08372 | Plant phosphoribosyltransferase C-terminal
Description: This domain is found at the C-terminus of phosphoribosyltransferases and phosphoribosyltransferase-like proteins. It contains putative transmembrane regions. It often appears together with calcium-ion dependent C2 domains (Pfam:PF00168).
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Ontology Term
Pfam:PF08429 | PLU-1-like protein
Description: Sequences in this family bear similarity to the central region of PLU-1 (Swiss:Q9Y3Q5). This is a nuclear protein that may have a role in DNA-binding and transcription, and is closely associated with the malignant phenotype of breast cancer [1]. This region is found in various other Jumonji/ARID domain-containing proteins (see Pfam:PF02373, Pfam:PF01388).
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Ontology Term
PANTHER:PTHR10694 | LYSINE-SPECIFIC DEMETHYLASE
 
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Ontology Term
PANTHER:PTHR10694:SF8 | LYSINE-SPECIFIC DEMETHYLASE LID
 
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Ontology Term
Pfam:PF02373 | JmjC domain, hydroxylase
Description: The JmjC domain belongs to the Cupin superfamily [3]. JmjC-domain proteins may be protein hydroxylases that catalyse a novel histone modification [4]. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation [5].
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Ontology Term
Pfam:PF02375 | jmjN domain
Description: NULL
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Ontology Term
Pfam:PF02928 | C5HC2 zinc finger
Description: Predicted zinc finger with eight potential zinc ligand binding residues. This domain is found in Jumonji [1]. This domain may have a DNA binding function.
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Ontology Term
Pfam:PF04107 | Glutamate-cysteine ligase family 2(GCS2)
Description: Also known as gamma-glutamylcysteine synthetase and gamma-ECS (EC:6.3.2.2). This enzyme catalyses the first and rate limiting step in de novo glutathione biosynthesis. Members of this family are found in archaea, bacteria and plants. May and Leaver [1] discuss the possible evolutionary origins of glutamate-cysteine ligase enzymes in different organisms and suggest that it evolved independently in different eukaryotes, from an ancestral bacterial enzyme. They also state that Arabidopsis thaliana gamma-glutamylcysteine synthetase is structurally unrelated to mammalian, yeast and Escherichia coli homologues. In plants, there are separate cytosolic and chloroplast forms of the enzyme.
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