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Search results 4301 to 4400 out of 202262 for *

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Category: OntologyTerm
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Type Details Score
Ontology Term
PANTHER:PTHR11998:SF13 | AP-4 COMPLEX SUBUNIT MU-1
 
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Ontology Term
PANTHER:PTHR14456 | INOSITOL POLYPHOSPHATE KINASE 1
 
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Ontology Term
PANTHER:PTHR14456:SF6 | INOSITOL-PENTAKISPHOSPHATE 2-KINASE
 
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Ontology Term
Pfam:PF06090 | Inositol-pentakisphosphate 2-kinase
Description: This is a family of inositol-pentakisphosphate 2-kinases (EC 2.7.1.158) (also known as inositol 1,3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase) and InsP5 2-kinase). This enzyme phosphorylates Ins(1,3,4,5,6)P5 to form Ins(1,2,3,4,5,6)P6 (also known as InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, nonhomologous end-joining, endocytosis and ion channel regulation.
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Ontology Term
PANTHER:PTHR19321 | PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED
 
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Ontology Term
Pfam:PF03999 | Microtubule associated protein (MAP65/ASE1 family)
Description: NULL
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Ontology Term
PANTHER:PTHR12103 | 5'-NUCLEOTIDASE DOMAIN-CONTAINING
 
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Ontology Term
Pfam:PF05761 | 5' nucleotidase family
Description: This family of eukaryotic proteins includes 5' nucleotidase enzymes, such as purine 5'-nucleotidase EC:3.1.3.5.
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Ontology Term
PANTHER:PTHR13600 | LEUCINE CARBOXYL METHYLTRANSFERASE
 
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Ontology Term
PANTHER:PTHR14445 | GRB10 INTERACTING GYF PROTEIN
 
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Ontology Term
Pfam:PF13320 | Domain of unknown function (DUF4091)
Description: This presumed domain is functionally uncharacterised. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 70 amino acids in length. There is a single completely conserved residue G that may be functionally important.
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Ontology Term
PANTHER:PTHR31116 | OS04G0501200 PROTEIN
 
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Ontology Term
Pfam:PF03352 | Methyladenine glycosylase
Description: The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.
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Ontology Term
Pfam:PF00045 | Hemopexin
Description: Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).
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Ontology Term
PANTHER:PTHR13286 | SAP30
 
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Ontology Term
Pfam:PF13867 | Sin3 binding region of histone deacetylase complex subunit SAP30
Description: This C-terminal domain of the SAP30 proteins appears to be the binding region for Sin3.
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Ontology Term
PANTHER:PTHR10942 | LEISHMANOLYSIN-LIKE PEPTIDASE
 
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Ontology Term
Pfam:PF01457 | Leishmanolysin
Description: NULL
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Ontology Term
Pfam:PF07974 | EGF-like domain
Description: This family contains EGF domains found in a variety of extracellular proteins.
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Ontology Term
PANTHER:PTHR11157 | FATTY ACID ACYL TRANSFERASE-RELATED
 
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Ontology Term
Pfam:PF01151 | GNS1/SUR4 family
Description: Members of this family are involved in long chain fatty acid elongation systems that produce the 26-carbon precursors for ceramide and sphingolipid synthesis [1]. Predicted to be integral membrane proteins, in eukaryotes they are probably located on the endoplasmic reticulum. Yeast ELO3 (Swiss:P40319) affects plasma membrane H+-ATPase activity, and may act on a glucose-signaling pathway that controls the expression of several genes that are transcriptionally regulated by glucose such as PMA1 [2].
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Ontology Term
PANTHER:PTHR16092 | SEC3/SYNTAXIN-RELATED
 
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Ontology Term
Pfam:PF09763 | Exocyst complex component Sec3
Description: This entry is the conserved middle and C-terminus of the Sec3 protein. Sec3 binds to the C-terminal cytoplasmic domain of GLYT1 (glycine transporter protein 1). Sec3 is the exocyst component that is closest to the plasma membrane docking site and it serves as a spatial landmark in the plasma membrane for incoming secretory vesicles. Sec3 is recruited to the sites of polarised membrane growth through its interaction with Rho1p, a small GTP-binding protein.
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Ontology Term
PANTHER:PTHR10993 | OCTANOYLTRANSFERASE
 
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Ontology Term
Pfam:PF03099 | Biotin/lipoate A/B protein ligase family
Description: This family includes biotin protein ligase, lipoate-protein ligase A and B. Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Each organism probably has only one BPL. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine [2]. Lipoate-protein ligase A (LPLA) catalyses the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes [3]. The unusual biosynthesis pathway of lipoic acid is mechanistically intertwined with attachment of the cofactor [5].
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Ontology Term
PANTHER:PTHR24286:SF0 | CYTOCHROME P450 61
 
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Ontology Term
PANTHER:PTHR10755 | COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL
 
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Ontology Term
PANTHER:PTHR10755:SF0 | OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL
 
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Ontology Term
PANTHER:PTHR12869 | SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN
 
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Ontology Term
Pfam:PF09767 | Predicted membrane protein (DUF2053)
Description: This entry is of the conserved N-terminal 150 residues of proteins conserved from plants to humans. The function is unknown although some annotation suggests it to be a transmembrane protein.
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Ontology Term
Pfam:PF08041 | PetM family of cytochrome b6f complex subunit 7
Description: This family consists of the PetM family of cytochrome b6f complex subunit IV. The cytochrome b6f complex consists of 7 subunits and contains 2 beta hemes and 1 chlorophyll alpha per cytochrome f. It is highly active in transferring electrons from decylplastoquinol to oxidised plastocyanin [1].
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Ontology Term
PANTHER:PTHR12383:SF1 | CHLOROPLAST PROCESSING PEPTIDASE
 
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Ontology Term
Pfam:PF10502 | Signal peptidase, peptidase S26
Description: This is a family of membrane signal serine endopeptidases which function in the processing of newly-synthesised secreted proteins. Peptidase S26 removes the hydrophobic, N-terminal, signal peptides as proteins are translocated across membranes. The active site residues take the form of a catalytic dyad that is Ser, Lys in subfamily S26A; the Ser is the nucleophile in catalysis, and the Lys is the general base.
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Ontology Term
PANTHER:PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN
 
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Ontology Term
Pfam:PF00079 | Serpin (serine protease inhibitor)
Description: Structure is a multi-domain fold containing a bundle of helices and a beta sandwich.
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Ontology Term
PANTHER:PTHR31696 | PROTEIN MIZU-KUSSEI 1
 
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Ontology Term
Pfam:PF02602 | Uroporphyrinogen-III synthase HemD
Description: This family consists of uroporphyrinogen-III synthase HemD EC:4.2.1.75 also known as Hydroxymethylbilane hydrolyase (cyclizing) from eukaryotes, bacteria and archaea. This enzyme catalyses the reaction: Hydroxymethylbilane <=> uroporphyrinogen-III + H(2)O. Some members of this family are multi-functional proteins possessing other enzyme activities related to porphyrin biosynthesis, such as Swiss:Q59294 with Pfam:PF00590, however the aligned region corresponds with the uroporphyrinogen-III synthase EC:4.2.1.75 activity only. Uroporphyrinogen-III synthase is the fourth enzyme in the heme pathway [2]. Mutant forms of the Uroporphyrinogen-III synthase gene cause congenital erythropoietic porphyria in humans a recessive inborn error of metabolism also known as Gunther disease [1].
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Ontology Term
Pfam:PF14295 | PAN domain
Description: NULL
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Ontology Term
PANTHER:PTHR13832:SF25 | PROTEIN PHOSPHATASE 2C 12-RELATED
 
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Ontology Term
PANTHER:PTHR12901 | SPERM PROTEIN HOMOLOG
 
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Ontology Term
Pfam:PF03364 | Polyketide cyclase / dehydrase and lipid transport
Description: This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. The family also includes proteins which are involved in the binding/transport of lipids.
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Ontology Term
PANTHER:PTHR13375 | FMS INTERACTING PROTEIN
 
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Ontology Term
PANTHER:PTHR13375:SF3 | THO COMPLEX SUBUNIT 5 HOMOLOG
 
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Ontology Term
Pfam:PF09766 | Fms-interacting protein/Thoc5
Description: This entry carries part of the crucial 144 N-terminal residues of the FmiP (Fms interacting protein). A member of the THO (suppressors of the transcriptional defects of hpr1delta by overexpression) complex which is a subcomplex of the transcription/export (TREX) complex [1]. It is essential for the binding of the protein to the cytoplasmic domain of activated Fms-molecules in M-CSF induced haematopoietic differentiation of macrophages. Fmip is also known as THOC5 (THO complex subunit 5) a 683 amino acids long protein which contains a nuclear localisation sequence (NLS), a leucine zipper and a PEST like sequence (aa. 303-319) that carries three ataxia-telangiectasia mutated (ATM) kinase specific phosphorylation sites. The C-terminus contains a THOC1 binding site [2]. The level of FMIP/Thoc5 expression might form a threshold that determines whether cells differentiate into macrophages or into granulocytes [3].
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Ontology Term
PANTHER:PTHR14155:SF2 | GH10160P
 
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Ontology Term
PANTHER:PTHR31896 | FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED
 
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Ontology Term
PANTHER:PTHR24115:SF277 | ATP BINDING MICROTUBULE MOTOR FAMILY PROTEIN-RELATED
 
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Ontology Term
PANTHER:PTHR13902:SF23 | SUBFAMILY NOT NAMED
 
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Ontology Term
PANTHER:PTHR10188 | L-ASPARAGINASE
 
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Ontology Term
Pfam:PF01112 | Asparaginase
Description: NULL
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Ontology Term
PANTHER:PTHR31988 | ESTERASE, PUTATIVE (DUF303)-RELATED
 
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Ontology Term
Pfam:PF03629 | Carbohydrate esterase, sialic acid-specific acetylesterase
Description: The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665 [1,2].
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Ontology Term
Pfam:PF05712 | MRG
Description: This family consists of three different eukaryotic proteins (mortality factor 4 (MORF4/MRG15), male-specific lethal 3(MSL-3) and ESA1-associated factor 3(EAF3)). It is thought that the MRG family is involved in transcriptional regulation via histone acetylation [1][2]. It contains 2 chromo domains and a leucine zipper motif [3].
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Ontology Term
Pfam:PF13943 | WPP domain
Description: NULL
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Ontology Term
PANTHER:PTHR22846 | WD40 REPEAT PROTEIN
 
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Ontology Term
PANTHER:PTHR22846:SF2 | F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN EBI
 
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Ontology Term
PANTHER:PTHR10177:SF100 | CYCLIN-A3-2-RELATED
 
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Ontology Term
Pfam:PF09177 | Syntaxin 6, N-terminal
Description: Members of this family, which are found in the amino terminus of various SNARE proteins, adopt a structure consisting of an antiparallel three-helix bundle. Their exact function has not been determined, though it is known that they regulate the SNARE motif, as well as mediate various protein-protein interactions involved in membrane-transport [1].
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Ontology Term
PANTHER:PTHR32379 | GUANIDINOACETATE N-METHYLTRANSFERASE
 
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Ontology Term
PANTHER:PTHR32379:SF0 | ARGININE N-METHYLTRANSFERASE 2
 
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Ontology Term
PANTHER:PTHR31807 | AUGMIN FAMILY MEMBER
 
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Ontology Term
Pfam:PF04484 | QWRF family
Description: AUG8 belongs to the plant QWRF motif-containing protein family, which also includes microtubule-associated protein ENDOSPERM DEFECTIVE 1 [1, 2] and SNOWY COTYLEDON 3 [3]. AUG8 binds the microtubule plus-end and participates in the reorientation of microtubules in hypocotyls (the stem of a germinating seedling) [4,5].
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Ontology Term
PANTHER:PTHR21494 | ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100
 
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Ontology Term
PANTHER:PTHR21494:SF0 | ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2
 
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Ontology Term
PANTHER:PTHR12354 | INTERFERON-RELATED DEVELOPMENTAL REGULATOR
 
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Ontology Term
PANTHER:PTHR12354:SF1 | LP04564P
 
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Ontology Term
Pfam:PF04836 | Interferon-related protein conserved region
Description: Family of proteins thought to be involved in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF [1].
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Ontology Term
Pfam:PF05004 | Interferon-related developmental regulator (IFRD)
Description: Interferon-related developmental regulator (IFRD1) is the human homologue of the rat early response protein PC4 and its murine homologue TIS7 [1]. The exact function of IFRD1 is unknown but it has been shown that PC4 is necessary to muscle differentiation and that it might have a role in signal transduction. This family also contains IFRD2 and its murine equivalent SKMc15 which are highly expressed soon after gastrulation and in the hepatic primordium, suggesting an involvement in early hematopoiesis [2].
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Ontology Term
PANTHER:PTHR22850:SF2 | DNA EXCISION REPAIR PROTEIN ERCC-8
 
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Ontology Term
PANTHER:PTHR21231:SF3 | GPN-LOOP GTPASE 2
 
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Ontology Term
PANTHER:PTHR24206 | OS06G0237300 PROTEIN
 
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Ontology Term
PANTHER:PTHR24031:SF71 | ATP-DEPENDENT RNA HELICASE DDX54
 
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Ontology Term
Pfam:PF08147 | DBP10CT (NUC160) domain
Description: This C terminal domain is found in the Dbp10p subfamily of hypothetical RNA helicases [1].
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Ontology Term
PANTHER:PTHR12000 | HEMOGLOBINASE FAMILY MEMBER
 
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Ontology Term
Pfam:PF01650 | Peptidase C13 family
Description: Members of this family are asparaginyl peptidases [1]. The blood fluke parasite Schistosoma mansoni has at least five Clan CA cysteine peptidases in its digestive tract including cathepsins B (2 isoforms), C, F and L. All have been recombinantly expressed as active enzymes, albeit in various stages of activation [2]. In addition, a Clan CD peptidase, termed asparaginyl endopeptidase or 'legumain' has been identified. This has formerly been characterised as a 'haemoglobinase', but this term is probably incorrect [2]. Two cDNAs have been described for Schistosoma mansoni legumain; one encodes an active enzyme whereas the active site cysteine residue encoded by the second cDNA is substituted by an asparagine residue. Both forms have been recombinantly expressed [3].
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Ontology Term
PANTHER:PTHR15660 | UNCHARACTERIZED
 
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Ontology Term
PANTHER:PTHR15660:SF1 | BRISC AND BRCA1-A COMPLEX MEMBER 1
 
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Ontology Term
PANTHER:PTHR11108 | FERROCHELATASE
 
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Ontology Term
Pfam:PF00762 | Ferrochelatase
Description: NULL
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Ontology Term
PANTHER:PTHR11995 | NADH DEHYDROGENASE
 
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Ontology Term
PANTHER:PTHR11995:SF2 | NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL
 
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Ontology Term
Pfam:PF01058 | NADH ubiquinone oxidoreductase, 20 Kd subunit
Description: NULL
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Ontology Term
PANTHER:PTHR31213 | FAMILY NOT NAMED
 
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Ontology Term
Pfam:PF10604 | Polyketide cyclase / dehydrase and lipid transport
Description: This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily [1].
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Ontology Term
Pfam:PF05875 | Ceramidase
Description: This family consists of several ceramidases. Ceramidases are enzymes involved in regulating cellular levels of ceramides, sphingoid bases, and their phosphates, EC:3.5.1.23. This family belongs to the CREST superfamily [2], which are distantly related to the GPCRs.
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Ontology Term
PANTHER:PTHR24301 | THROMBOXANE-A SYNTHASE
 
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Ontology Term
PANTHER:PTHR24301:SF2 | THROMBOXANE-A SYNTHASE
 
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Ontology Term
PANTHER:PTHR24089:SF0 | MITOCHONDRIAL CARRIER PROTEIN COAC2
 
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Ontology Term
PANTHER:PTHR24031:SF84 | EUKARYOTIC INITIATION FACTOR 4A
 
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Ontology Term
PANTHER:PTHR11533 | PROTEASE M1 ZINC METALLOPROTEASE
 
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Ontology Term
Pfam:PF01433 | Peptidase family M1 domain
Description: Members of this family are aminopeptidases. The members differ widely in specificity, hydrolysing acidic, basic or neutral N-terminal residues. This family includes leukotriene-A4 hydrolase Swiss:P09960, this enzyme also has an aminopeptidase activity [1].
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Ontology Term
PANTHER:PTHR10501:SF0 | NUCLEIC ACID/NUCLEOTIDE BINDING PROTEIN
 
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Ontology Term
Pfam:PF02353 | Mycolic acid cyclopropane synthetase
Description: This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyse the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
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Ontology Term
Pfam:PF02325 | YGGT family
Description: This family includes subunit CCB3 of cofactor assembly complex C, involved in c-type cytochrome maturation in photosynthetic organisms [1]. This family also includes uncharacterised protein YggT, associated with bacteria outside the cyanobacteria.
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Ontology Term
PANTHER:PTHR24093:SF124 | COPPER-TRANSPORTING ATPASE PAA1, CHLOROPLASTIC
 
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Ontology Term
PANTHER:PTHR13308 | UNCHARACTERIZED
 
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Ontology Term
Pfam:PF08590 | Domain of unknown function (DUF1771)
Description: This domain is highly charged and may represent a small helical extension of the Smr domain (Pfam:PF01713), known as N-ext, whose function is not yet clear [1].
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Ontology Term
Pfam:PF04851 | Type III restriction enzyme, res subunit
Description: NULL
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Ontology Term
PANTHER:PTHR14068 | EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED
 
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Ontology Term
PANTHER:PTHR12126 | NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED
 
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