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Search results 601 to 700 out of 202262 for *

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Categories

Category: OntologyTerm
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Type Details Score
Ontology Term
PANTHER:PTHR19876 | COATOMER
 
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Ontology Term
PANTHER:PTHR19876:SF1 | COATOMER SUBUNIT ALPHA
 
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Ontology Term
PANTHER:PTHR13620 | 3-5 EXONUCLEASE
 
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Ontology Term
Pfam:PF01612 | 3'-5' exonuclease
Description: This domain is responsible for the 3'-5' exonuclease proofreading activity of E. coli DNA polymerase I (polI) and other enzymes, it catalyses the hydrolysis of unpaired or mismatched nucleotides. This domain consists of the amino-terminal half of the Klenow fragment in E. coli polI it is also found in the Werner syndrome helicase (WRN), focus forming activity 1 protein (FFA-1) and ribonuclease D (RNase D). Werner syndrome is a human genetic disorder causing premature aging; the WRN protein has helicase activity in the 3'-5' direction [4,5]. The FFA-1 protein is required for formation of a replication foci and also has helicase activity; it is a homologue of the WRN protein [3]. RNase D is a 3'-5' exonuclease involved in tRNA processing. Also found in this family is the autoantigen PM/Scl thought to be involved in polymyositis-scleroderma overlap syndrome.
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Ontology Term
PANTHER:PTHR11795 | BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN LIVH
 
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Ontology Term
Pfam:PF00139 | Legume lectin domain
Description: NULL
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Ontology Term
PANTHER:PTHR11556 | FRUCTOSE-1,6-BISPHOSPHATASE-RELATED
 
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Ontology Term
PANTHER:PTHR11556:SF7 | FRUCTOSE-1,6-BISPHOSPHATASE, CHLOROPLASTIC
 
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Ontology Term
Pfam:PF00316 | Fructose-1-6-bisphosphatase, N-terminal domain
Description: This family represents the N-terminus of this protein family.
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Ontology Term
PANTHER:PTHR11439:SF127 | TRANSPOSON TY4-H GAG POLYPROTEIN-RELATED
 
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Ontology Term
PANTHER:PTHR11709:SF9 | LACCASE-7
 
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Ontology Term
PANTHER:PTHR24326 | HOMEOBOX-LEUCINE ZIPPER PROTEIN
 
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Ontology Term
PANTHER:PTHR10052 | 60S RIBOSOMAL PROTEIN L18A
 
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Ontology Term
Pfam:PF01775 | Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Description: This family includes: archaeal 50S ribosomal protein L18Ae, often referred to as L20e or LX; fungal 60S ribosomal protein L20; and higher eukaryote 60S ribosomal protein L18A.
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Ontology Term
PANTHER:PTHR10527 | IMPORTIN BETA
 
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Ontology Term
PANTHER:PTHR10527:SF5 | KARYOPHERIN (IMPORTIN) BETA 3
 
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Ontology Term
PANTHER:PTHR31390 | EXPRESSED PROTEIN
 
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Ontology Term
Pfam:PF12043 | Domain of unknown function (DUF3527)
Description: This presumed domain is functionally uncharacterised. This domain is found in eukaryotes. This domain is about 120 amino acids in length. This domain has a conserved CDCGGWD sequence motif.
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Ontology Term
PANTHER:PTHR10799 | SNF2/RAD54 HELICASE FAMILY
 
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Ontology Term
Pfam:PF05282 | AAR2 protein
Description: This family consists of several eukaryotic AAR2-like proteins. The yeast protein AAR2 is involved in splicing pre-mRNA of the a1 cistron and other genes that are important for cell growth [1].
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Ontology Term
PANTHER:PTHR31917 | AGENET DOMAIN-CONTAINING PROTEIN-RELATED
 
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Ontology Term
Pfam:PF01426 | BAH domain
Description: This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction [3].
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Ontology Term
Pfam:PF09174 | Maf1 regulator
Description: Maf1 is a negative regulator of RNA polymerase III [1][2]. It targets the initiation factor TFIIIB [3].
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Ontology Term
PANTHER:PTHR21290 | SPHINGOMYELIN SYNTHETASE
 
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Ontology Term
PANTHER:PTHR21290:SF1 | PHOSPHATIDYLINOSITOL:CERAMIDE INOSITOLPHOSPHOTRANSFERASE 1-RELATED
 
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Ontology Term
Pfam:PF14360 | PAP2 superfamily C-terminal
Description: This family is closely related to the C-terminal a region of PAP2.
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Ontology Term
PANTHER:PTHR24031:SF76 | ATP-DEPENDENT RNA HELICASE DDX6-RELATED
 
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Ontology Term
PANTHER:PTHR11102 | SEL-1-LIKE PROTEIN
 
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Ontology Term
Pfam:PF08238 | Sel1 repeat
Description: This short repeat is found in the Sel1 protein [1]. It is related to TPR repeats.
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Ontology Term
PANTHER:PTHR23012 | RING/FYVE/PHD ZINC FINGER DOMAIN-CONTAINING
 
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Ontology Term
Pfam:PF12906 | RING-variant domain
Description: NULL
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Ontology Term
PANTHER:PTHR24015:SF44 | SUBFAMILY NOT NAMED
 
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Ontology Term
PANTHER:PTHR12197 | HISTONE-LYSINE N-METHYLTRANSFERASE SMYD
 
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Ontology Term
PANTHER:PTHR12197:SF13 | HISTONE-LYSINE N-METHYLTRANSFERASE ASHR2
 
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Ontology Term
PANTHER:PTHR11527 | HEAT-SHOCK PROTEIN 20 FAMILY MEMBER
 
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Ontology Term
Pfam:PF00011 | Hsp20/alpha crystallin family
Description: Not only do small heat-shock-proteins occur in eukaryotes and prokaryotes but they have also now been shown to occur in cyanobacterial phages as well as their bacterial hosts [2].
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Ontology Term
PANTHER:PTHR12483 | SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS
 
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Ontology Term
Pfam:PF04145 | Ctr copper transporter family
Description: The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high-affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane. A series of clustered methionine residues in the hydrophilic extracellular domain, and an MXXXM motif in the second transmembrane domain, are important for copper uptake. These methionine probably coordinate copper during the process of metal transport.
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Ontology Term
PANTHER:PTHR11785 | AMINO ACID TRANSPORTER
 
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Ontology Term
Pfam:PF13520 | Amino acid permease
Description: NULL
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Ontology Term
PANTHER:PTHR31669 | PROTEIN FAR1-RELATED SEQUENCE 10-RELATED
 
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Ontology Term
PANTHER:PTHR31669:SF0 | FAR-RED IMPAIRED RESPONSIVE (FAR1) FAMILY PROTEIN-RELATED
 
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Ontology Term
PANTHER:PTHR31964 | ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN
 
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Ontology Term
Pfam:PF00582 | Universal stress protein family
Description: The universal stress protein UspA Swiss:P28242 [1] is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA [3] reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP [2], though UspA lacks ATP-binding activity.
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Ontology Term
Pfam:PF00043 | Glutathione S-transferase, C-terminal domain
Description: GST conjugates reduced glutathione to a variety of targets including S-crystallin from squid, the eukaryotic elongation factor 1-gamma, the HSP26 family of stress-related proteins and auxin-regulated proteins in plants. Stringent starvation proteins in E. coli are also included in the alignment but are not known to have GST activity. The glutathione molecule binds in a cleft between N and C-terminal domains. The catalytically important residues are proposed to reside in the N-terminal domain [1]. In plants, GSTs are encoded by a large gene family (48 GST genes in Arabidopsis) and can be divided into the phi, tau, theta, zeta, and lambda classes [2].
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Ontology Term
PANTHER:PTHR11260 | GLUTATHIONE S-TRANSFERASE, GST, SUPERFAMILY, GST DOMAIN CONTAINING
 
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Ontology Term
PANTHER:PTHR11260:SF16 | GLUTATHIONE S-TRANSFERASE, N-TERMINAL DOMAIN CONTAINING PROTEIN, EXPRESSED
 
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Ontology Term
Pfam:PF13417 | Glutathione S-transferase, N-terminal domain
Description: NULL
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Ontology Term
PANTHER:PTHR11260:SF39 | GLUTATHIONE S-TRANSFERASE U1-RELATED
 
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Ontology Term
Pfam:PF03759 | PRONE (Plant-specific Rop nucleotide exchanger)
Description: This is a functional guanine exchange factor (GEF) of plant Rho GTPase [3].
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Ontology Term
Pfam:PF14368 | Probable lipid transfer
Description: The members of this family are probably involved in lipid transfer. The family has several highly conserved cysteines, paired in various ways.
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Ontology Term
PANTHER:PTHR11038 | MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10
 
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Ontology Term
Pfam:PF02953 | Tim10/DDP family zinc finger
Description: Putative zinc binding domain with four conserved cysteine residues. This domain is found in the human disease protein Swiss:O60220. Members of this family such as Tim9 and Tim10 are involved in mitochondrial protein import [1]. Members of this family seem to be localised to the mitochondrial intermembrane space [2].
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Ontology Term
PANTHER:PTHR11654 | OLIGOPEPTIDE TRANSPORTER-RELATED
 
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Ontology Term
Pfam:PF00854 | POT family
Description: The POT (proton-dependent oligopeptide transport) family all appear to be proton dependent transporters [1].
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Ontology Term
Pfam:PF07526 | Associated with HOX
Description: The function of this domain is unknown [1]. It is often found in plant proteins associated with Pfam:PF00046.
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Ontology Term
Pfam:PF01221 | Dynein light chain type 1
Description: NULL
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Ontology Term
PANTHER:PTHR31276 | FAMILY NOT NAMED
 
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Ontology Term
Pfam:PF04759 | Protein of unknown function, DUF617
Description: This family represents a conserved region in a number of uncharacterised plant proteins.
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Ontology Term
PANTHER:PTHR11654:SF20 | PROTEIN NRT1/ PTR FAMILY 2.13
 
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Ontology Term
PANTHER:PTHR31038 | EXPRESSED PROTEIN-RELATED
 
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Ontology Term
Pfam:PF11891 | Protein RETICULATA-related
Description: This entry represents RETICULATA and related proteins from plants. Arabidopsis RETICULATA protein is involved in differential development of bundle sheath and mesophyll cell chloroplasts [1].
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Ontology Term
PANTHER:PTHR12859 | PRA1 PROTEIN
 
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Ontology Term
PANTHER:PTHR12859:SF0 | PRA1 FAMILY PROTEIN
 
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Ontology Term
Pfam:PF03208 | PRA1 family protein
Description: This family includes the PRA1 (Prenylated rab acceptor) protein which is a Rab guanine dissociation inhibitor (GDI) displacement factor [2]. This family also includes the glutamate transporter EAAC1 interacting protein GTRAP3-18 [3].
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Ontology Term
PANTHER:PTHR11063 | GLUTAMATE SEMIALDEHYDE DEHYDROGENASE
 
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Ontology Term
PANTHER:PTHR11732:SF34 | ALDO-KETO REDUCTASE
 
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Ontology Term
Pfam:PF02330 | Mitochondrial glycoprotein
Description: This mitochondrial matrix protein family contains members of the MAM33 family which bind to the globular 'heads' of C1Q. It is thought to be involved in mitochondrial oxidative phosphorylation and in nucleus-mitochondrion interactions [1].
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Ontology Term
Pfam:PF01991 | ATP synthase (E/31 kDa) subunit
Description: This family includes the vacuolar ATP synthase E subunit [1], as well as the archaebacterial ATP synthase E subunit [2].
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Ontology Term
Pfam:PF14770 | Transmembrane protein 18
Description: The function of this family is not known, however it is predicted to be a three-pass membrane protein.
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Ontology Term
PANTHER:PTHR11540 | MALATE AND LACTATE DEHYDROGENASE
 
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Ontology Term
Pfam:PF02866 | lactate/malate dehydrogenase, alpha/beta C-terminal domain
Description: L-lactate dehydrogenases are metabolic enzymes which catalyse the conversion of L-lactate to pyruvate, the last step in anaerobic glycolysis. L-2-hydroxyisocaproate dehydrogenases are also members of the family. Malate dehydrogenases catalyse the interconversion of malate to oxaloacetate. The enzyme participates in the citric acid cycle. L-lactate dehydrogenase is also found as a lens crystallin in bird and crocodile eyes.
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Ontology Term
PANTHER:PTHR13902 | SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED
 
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Ontology Term
PANTHER:PTHR13902:SF5 | SERINE/THREONINE-PROTEIN KINASE-LIKE PROTEIN-RELATED
 
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Ontology Term
PANTHER:PTHR11119 | XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER
 
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Ontology Term
Pfam:PF00860 | Permease family
Description: This family includes permeases for diverse substrates such as xanthine Swiss:P42086, uracil Swiss:P39766 and vitamin C Swiss:Q9UGH3. However many members of this family are functionally uncharacterised and may transport other substrates. Members of this family have ten predicted transmembrane helices.
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Ontology Term
PANTHER:PTHR23138 | RAN BINDING PROTEIN
 
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Ontology Term
Pfam:PF00638 | RanBP1 domain
Description: NULL
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Ontology Term
PANTHER:PTHR24310 | FAMILY NOT NAMED
 
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Ontology Term
PANTHER:PTHR10811 | FRINGE-RELATED
 
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Ontology Term
PANTHER:PTHR10811:SF5 | FRINGE GLYCOSYLTRANSFERASE
 
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Ontology Term
Pfam:PF04646 | Protein of unknown function, DUF604
Description: This family includes a conserved region found in several uncharacterised plant proteins.
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Ontology Term
Pfam:PF08241 | Methyltransferase domain
Description: Members of this family are SAM dependent methyltransferases.
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Ontology Term
Pfam:PF08631 | Meiosis protein SPO22/ZIP4 like
Description: SPO22/ZIP4 in yeast is a meiosis specific protein involved in sporulation [1]. It has been shown to regulate crossover distribution by promoting synaptonemal complex formation [3].
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Ontology Term
PANTHER:PTHR24420:SF525 | L-TYPE LECTIN-DOMAIN CONTAINING RECEPTOR KINASE IV.1-RELATED
 
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Ontology Term
PANTHER:PTHR31048 | OS03G0233200 PROTEIN
 
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Ontology Term
Pfam:PF00314 | Thaumatin family
Description: NULL
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Ontology Term
PANTHER:PTHR12942 | STEP II SPLICING FACTOR SLU7
 
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Ontology Term
Pfam:PF11708 | Pre-mRNA splicing Prp18-interacting factor
Description: The spliceosome, an assembly of snRNAs (U1, U2, U4/U6, and U5) and proteins, catalyses the excision of introns from pre-mRNAs in two successive trans-esterification reactions. Step 2 depends upon integral spliceosome constituents such as U5 snRNA and Prp8 and non-spliceosomal proteins Prp16, Slu7, Prp18, and Prp22. ATP hydrolysis by the DEAH-box enzyme Prp16 promotes a conformational change in the spliceosome that leads to protection of the 3'ss from targeted RNase H cleavage. This change, which probably reflects binding of the 3'ss PyAG in the catalytic centre of the spliceosome, requires the ordered recruitment of Slu7, Prp18, and Prp22 to the spliceosome. There is a close functional relationship between Prp8, Prp18, and Slu7, and Prp18 interacts with Slu7, so that together they recruit Prp22 to the spliceosome. Most members of the family carry a zinc-finger of the CCHC-type upstream of this domain.
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Ontology Term
Pfam:PF02358 | Trehalose-phosphatase
Description: This family consist of trehalose-phosphatases EC:3.1.3.12 these enzyme catalyse the de-phosphorylation of trehalose-6-phosphate to trehalose and orthophosphate. The aligned region is present in trehalose-phosphatases and comprises the entire length of the protein it is also found in the C-terminus of trehalose-6-phosphate synthase EC:2.4.1.15 adjacent to the trehalose-6-phosphate synthase domain - Pfam:PF00982. It would appear that the two equivalent genes in the E. coli otsBA operon [2] otsA the trehalose-6-phosphate synthase and otsB trehalose-phosphatase (this family) have undergone gene fusion in most eukaryotes e.g. Swiss:P31688 and Swiss:P93653. Trehalose is a common disaccharide of bacteria, fungi and invertebrates that appears to play a major role in desiccation tolerance [1].
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Ontology Term
PANTHER:PTHR13011 | TFIIF-ALPHA
 
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Ontology Term
PANTHER:PTHR13011:SF0 | GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1
 
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Ontology Term
Pfam:PF05793 | Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
Description: Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) or RNA polymerase II-associating protein 74 (RAP74) is the large subunit of transcription factor IIF (TFIIF), which is essential for accurate initiation and stimulates elongation by RNA polymerase II [1].
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Ontology Term
PANTHER:PTHR11709:SF25 | LACCASE-1-RELATED
 
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Ontology Term
Pfam:PF01070 | FMN-dependent dehydrogenase
Description: NULL
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Ontology Term
PANTHER:PTHR19139:SF52 | AQUAPORIN TIP1-1-RELATED
 
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Ontology Term
PANTHER:PTHR22820 | SH2 DOMAIN ADAPTOR PROTEIN
 
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Ontology Term
PANTHER:PTHR22820:SF9 | PROTEIN ENHANCER OF SEVENLESS 2B
 
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Ontology Term
PANTHER:PTHR31221 | WRKY TRANSCRIPTION FACTOR PROTEIN 1-RELATED
 
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Ontology Term
PANTHER:PTHR12725 | HALOACID DEHALOGENASE-LIKE HYDROLASE
 
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