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Search results 6001 to 6100 out of 202262 for *

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Categories

Category: OntologyTerm
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Type Details Score
Ontology Term
PANTHER:PTHR13108 | CONDENSIN COMPLEX SUBUNIT 2
 
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Ontology Term
PANTHER:PTHR13108:SF9 | CONDENSIN COMPLEX SUBUNIT 2
 
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Ontology Term
Pfam:PF05786 | Condensin complex subunit 2
Description: This family consists of several Barren protein homologues from several eukaryotic organisms. In Drosophila Barren (barr) is required for sister-chromatid segregation in mitosis. barr encodes a novel protein that is present in proliferating cells and has homologues in yeast and human. Mitotic defects in barr embryos become apparent during cycle 16, resulting in a loss of PNS and CNS neurons. Centromeres move apart at the metaphase-anaphase transition and Cyclin B is degraded, but sister chromatids remain connected, resulting in chromatin bridging. Barren protein localises to chromatin throughout mitosis. Colocalisation and biochemical experiments indicate that Barren associates with Topoisomerase II throughout mitosis and alters the activity of Topoisomerase II. It has been suggested that this association is required for proper chromosomal segregation by facilitating the decatenation of chromatids at anaphase [1]. This family forms one of the three non-structural maintenance of chromosomes (SMC) subunits of the mitotic condensation complex along with Cnd1 and Cnd3 [4].
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Ontology Term
PANTHER:PTHR23389 | CHROMOSOME TRANSMISSION FIDELITY FACTOR 18
 
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Ontology Term
Pfam:PF01930 | Domain of unknown function DUF83
Description: This domain has no known function. The domain contains three conserved cysteines at its C terminus.
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Ontology Term
Pfam:PF08696 | DNA replication factor Dna2
Description: Dna2 is a DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, ( 5'-flap endonuclease) and helicase activities. It is required for Okazaki fragment processing and is involved in DNA repair pathways [1].
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Ontology Term
PANTHER:PTHR10252:SF5 | DR1-ASSOCIATED COREPRESSOR
 
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Ontology Term
Pfam:PF14639 | Holliday-junction resolvase-like of SPT6
Description: The YqgF domain of SPT6 proteins is homologous to the E.coli RuvC [1] but its putative catalytic site lacks the carboxylate side chains critical for coordinating magnesium ions that mediate phosphodiester bond-cleavage [2]
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Ontology Term
Pfam:PF04873 | Ethylene insensitive 3
Description: Ethylene insensitive 3 (EIN3) proteins are a family of plant DNA-binding proteins that regulate transcription in response to the gaseous plant hormone ethylene, and are essential for ethylene-mediated responses including the triple response, cell growth inhibition, and accelerated senescence.
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Ontology Term
PANTHER:PTHR13165:SF0 | SERRATE RNA EFFECTOR MOLECULE HOMOLOG
 
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Ontology Term
Pfam:PF14966 | DNA repair REX1-B
Description: This family of proteins includes Chlamydomonas reinhardtii REX1-B (Required for Excision 1-B) which is involved in a light-independent DNA repair pathway [1].
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Ontology Term
PANTHER:PTHR24092:SF7 | PROTEIN TAT-3
 
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Ontology Term
Pfam:PF13243 | Squalene-hopene cyclase C-terminal domain
Description: Squalene-hopene cyclase, EC:5.4.99.17, catalyses the cyclisation of squalene into hopene in bacteria. This reaction is part of a cationic cyclisation cascade, which is homologous to a key step in cholesterol biosynthesis. This family is the C-terminal half of the molecule.
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Ontology Term
PANTHER:PTHR10188:SF6 | N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE
 
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Ontology Term
PANTHER:PTHR11804 | PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED
 
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Ontology Term
PANTHER:PTHR11804:SF5 | OLIGOENDOPEPTIDASE F
 
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Ontology Term
Pfam:PF02597 | ThiS family
Description: ThiS (thiaminS) is a 66 aa protein involved in sulphur transfer Swiss:O32583. ThiS is coded in the thiCEFSGH operon in E. coli. This family of proteins have two conserved Glycines at the COOH terminus. Thiocarboxylate is formed at the last G in the activation process. Sulphur is transferred from ThiI to ThiS in a reaction catalysed by IscS [1]. MoaD, Swiss:P30748 a protein involved sulphur transfer in molybdopterin synthesis, is about the same length and shows limited sequence similarity to ThiS. Both have the conserved GG at the COOH end.
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Ontology Term
PANTHER:PTHR31533 | GPI-ANCHORED PROTEIN LLG1-RELATED-RELATED
 
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Ontology Term
PANTHER:PTHR23139:SF9 | SPLICING FACTOR U2AF 65 KDA SUBUNIT
 
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Ontology Term
PANTHER:PTHR21304:SF0 | MICOS COMPLEX SUBUNIT MIC10
 
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Ontology Term
PANTHER:PTHR20861 | HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE
 
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Ontology Term
PANTHER:PTHR20861:SF1 | HOMOSERINE KINASE
 
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Ontology Term
PANTHER:PTHR24015:SF74 | SUBFAMILY NOT NAMED
 
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Ontology Term
PANTHER:PTHR31110 | PESTICIDAL CRYSTAL CRY8BA PROTEIN
 
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Ontology Term
PANTHER:PTHR14140 | E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED
 
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Ontology Term
PANTHER:PTHR32077:SF3 | FASCICLIN-LIKE ARABINOGALACTAN PROTEIN 7
 
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Ontology Term
PANTHER:PTHR23198 | NUCLEOPORIN
 
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Ontology Term
PANTHER:PTHR23198:SF0 | NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96
 
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Ontology Term
Pfam:PF04096 | Nucleoporin autopeptidase
Description: The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins [2]. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore [3].
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Ontology Term
Pfam:PF12110 | Nuclear protein 96
Description: Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex. [1] [2]
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Ontology Term
Pfam:PF00476 | DNA polymerase family A
Description: NULL
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Ontology Term
PANTHER:PTHR11430 | LIPOCALIN
 
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Ontology Term
PANTHER:PTHR11430:SF32 | CHLOROPLASTIC LIPOCALIN
 
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Ontology Term
PANTHER:PTHR12805 | KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG
 
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Ontology Term
PANTHER:PTHR12805:SF0 | DNA/RNA-BINDING PROTEIN KIN17
 
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Ontology Term
Pfam:PF10357 | Domain of Kin17 curved DNA-binding protein
Description: Kin17_mid is the conserved central 169 residue region of a family of Kin17 proteins. Towards the N-terminal end there is a zinc-finger domain, and in human and mouse members there is a RecA-like domain further downstream. The Kin17 protein in humans forms intra-nuclear foci during cell proliferation and is re-distributed in the nucleoplasm during the cell cycle [1].
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Ontology Term
PANTHER:PTHR13228 | CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5
 
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Ontology Term
PANTHER:PTHR13228:SF3 | CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5
 
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Ontology Term
Pfam:PF10392 | Golgi transport complex subunit 5
Description: The COG complex, the peripheral membrane oligomeric protein complex involved in intra-Golgi protein trafficking, consists of eight subunits arranged in two lobes bridged by Cog1. Cog5 is in the smaller, B lobe, bound in with Cog6-8, and is itself bound to Cog1 as well as, strongly, to Cog7.
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Ontology Term
PANTHER:PTHR11959 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE
 
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Ontology Term
PANTHER:PTHR11959:SF1 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE
 
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Ontology Term
PANTHER:PTHR31480 | BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE
 
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Ontology Term
Pfam:PF00494 | Squalene/phytoene synthase
Description: NULL
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Ontology Term
Pfam:PF12313 | NPR1/NIM1 like defence protein C terminal
Description: This family of proteins is found in eukaryotes. Proteins in this family are typically between 251 and 588 amino acids in length. The family is found in association with Pfam:PF00023, Pfam:PF00651. There are two conserved sequence motifs: LENRV and DLN. NPR1 (NIM1) is a defence protein in many plant species.
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Ontology Term
PANTHER:PTHR13439 | CT120 PROTEIN
 
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Ontology Term
PANTHER:PTHR13439:SF0 | TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4
 
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Ontology Term
PANTHER:PTHR12862 | BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN
 
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Ontology Term
Pfam:PF01869 | BadF/BadG/BcrA/BcrD ATPase family
Description: This family includes the BadF Swiss:O07462 and BadG Swiss:O07463 proteins that are two subunits of Benzoyl-CoA reductase, that may be involved in ATP hydrolysis. The family also includes an activase subunit from the enzyme 2-hydroxyglutaryl-CoA dehydratase Swiss:P11568. The protein Swiss:O66634 contains two copies of this region suggesting that the family may structurally dimerise. This family appears to be related to Pfam:PF00370.
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Ontology Term
PANTHER:PTHR10799:SF70 | CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1
 
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Ontology Term
Pfam:PF13907 | Domain of unknown function (DUF4208)
Description: This domain is found at the C-terminus of chromodomain-helicase-DNA-binding proteins. The exact function of the domain is undetermined.
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Ontology Term
PANTHER:PTHR10229 | GTP-BINDING PROTEIN HFLX
 
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Ontology Term
PANTHER:PTHR10229:SF0 | GTP-BINDING PROTEIN 6-RELATED
 
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Ontology Term
PANTHER:PTHR22870:SF90 | REGULATOR OF CHROMOSOME CONDENSATION-LIKE PROTEIN WITH FYVE ZINC FINGER DOMAIN-RELATED
 
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Ontology Term
PANTHER:PTHR31208 | EXPRESSED PROTEIN
 
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Ontology Term
Pfam:PF04178 | Got1/Sft2-like family
Description: Traffic through the yeast Golgi complex depends on a member of the syntaxin family of SNARE proteins, Sed5, present in early Golgi cisternae. Got1 is thought to facilitate Sed5-dependent fusion events [1]. This is a family of sequences derived from eukaryotic proteins. They are similar to a region of a SNARE-like protein required for traffic through the Golgi complex, SFT2 protein (Swiss:P38166) [2]. This is a conserved protein with four putative transmembrane helices, thought to be involved in vesicular transport in later Golgi compartments [1].
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Ontology Term
Pfam:PF13616 | PPIC-type PPIASE domain
Description: Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.
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Ontology Term
PANTHER:PTHR22630 | PRE-MRNA BRANCH SITE PROTEIN
 
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Ontology Term
PANTHER:PTHR22630:SF0 | PRE-MRNA BRANCH SITE PROTEIN P14
 
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Ontology Term
PANTHER:PTHR10277 | HOMOCITRATE SYNTHASE-RELATED
 
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Ontology Term
PANTHER:PTHR10277:SF1 | PROTEIN Y71G12B.10
 
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Ontology Term
Pfam:PF00682 | HMGL-like
Description: This family contains a diverse set of enzymes. These include various aldolases and a region of pyruvate carboxylase.
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Ontology Term
PANTHER:PTHR12075:SF0 | TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 9
 
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Ontology Term
PANTHER:PTHR31459 | FAMILY NOT NAMED
 
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Ontology Term
Pfam:PF08637 | ATP synthase regulation protein NCA2
Description: NCA2 has been shown to be required for the regulation of ATP synthase subunits Atp6p and Atp8p in Saccharomyces cerevisiae [1].
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Ontology Term
PANTHER:PTHR11595 | EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER
 
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Ontology Term
Pfam:PF00736 | EF-1 guanine nucleotide exchange domain
Description: This family is the guanine nucleotide exchange domain of EF-1 beta and EF-1 delta chains.
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Ontology Term
Pfam:PF01730 | UreF
Description: This family consists of the Urease accessory protein UreF. The urease enzyme (urea amidohydrolase) hydrolyses urea into ammonia and carbamic acid [2]. UreF is proposed to modulate the activation process of urease by eliminating the binding of nickel irons to noncarbamylated protein [1].
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Ontology Term
PANTHER:PTHR11753:SF5 | AP COMPLEX SUBUNIT SIGMA
 
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Ontology Term
PANTHER:PTHR10556:SF28 | VERY-LONG-CHAIN ENOYL-COA REDUCTASE
 
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Ontology Term
PANTHER:PTHR11353:SF22 | T-COMPLEX PROTEIN 1 SUBUNIT ETA
 
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Ontology Term
PANTHER:PTHR12581 | HIV-1 REV BINDING PROTEIN 2, 3
 
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Ontology Term
PANTHER:PTHR24411 | NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR
 
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Ontology Term
PANTHER:PTHR10192 | MOLYBDOPTERIN BIOSYNTHESIS PROTEIN
 
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Ontology Term
Pfam:PF03453 | MoeA N-terminal region (domain I and II)
Description: This family contains two structural domains. One of these contains the conserved DGXA motif. This region is found in proteins involved in biosynthesis of molybdopterin cofactor however the exact molecular function of this region is uncertain.
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Ontology Term
Pfam:PF03454 | MoeA C-terminal region (domain IV)
Description: This domain is found in proteins involved in biosynthesis of molybdopterin cofactor however the exact molecular function of this domain is uncertain. The structure of this domain is known [1] and forms an incomplete beta barrel.
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Ontology Term
PANTHER:PTHR10986 | 39S RIBOSOMAL PROTEIN L20
 
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Ontology Term
Pfam:PF00453 | Ribosomal protein L20
Description: NULL
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Ontology Term
PANTHER:PTHR18937:SF8 | CHROMOSOME-ASSOCIATED PROTEIN, ISOFORM A
 
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Ontology Term
PANTHER:PTHR12416 | UNCHARACTERIZED
 
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Ontology Term
Pfam:PF04900 | Fcf1
Description: Fcf1 is a nucleolar protein involved in pre-rRNA processing [1]. Depletion of yeast Fcf1 and Fcf2 leads to a decrease in synthesis of the 18S rRNA and results in a deficit in 40S ribosomal subunits [1].
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Ontology Term
Pfam:PF14703 | Cytosolic domain of 10TM putative phosphate transporter
Description: PHM7_cyt is the predicted cytosolic domain of integral membrane proteins, such as yeast PHM7 and TM63A_HUMAN TRANSMEMBRANE PROTEIN 63A, SwissProt:O94886. This domain usually precedes the 7TM region, Pfam:PF02714, and follows a RSN1_TM, Pfam:PF13967. Fold recognition programs consistently and with high significance predict this domain to be distantly homologous to RNA binding proteins from the RRM clan.
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Ontology Term
PANTHER:PTHR25952 | ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN
 
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Ontology Term
Pfam:PF02221 | ML domain
Description: ML domain - MD-2-related lipid recognition domain. This family consists of proteins from plants, animals and fungi, including dust mite allergen Der P 2 (Swiss:P49278). It has been implicate in lipid recognition, particularly in the recognition of pathogen related products. A mutation in Npc2 (Swiss:Q15668) causes a rare form of Niemann-Pick type C2 disease. This domain has a similar topology to immunoglobulin domains.
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Ontology Term
Pfam:PF14647 | FAM91 N-terminus
Description: NULL
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Ontology Term
Pfam:PF14648 | FAM91 C-terminus
Description: NULL
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Ontology Term
PANTHER:PTHR23333 | UBX DOMAIN CONTAINING PROTEIN
 
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Ontology Term
Pfam:PF08059 | SEP domain
Description: The SEP domain is named after Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47. In p47, the SEP domain has been shown to bind to and inhibit the cysteine protease cathepsin L [1]. Most SEP domains are succeeded closely by a UBX domain [1].
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Ontology Term
PANTHER:PTHR10584:SF8 | TRANSMEMBRANE PROTEIN 256
 
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Ontology Term
Pfam:PF04241 | Protein of unknown function (DUF423)
Description: This family of proteins with unknown function is a possible integral membrane protein from Caenorhabditis elegans. This family of proteins has GO references indicating the protein is involved in nematode larval development and is a positive regulator of growth rate.
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Ontology Term
PANTHER:PTHR11124 | VACUOLAR SORTING PROTEIN VPS29
 
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Ontology Term
Pfam:PF12850 | Calcineurin-like phosphoesterase superfamily domain
Description: Members of this family are part of the Calcineurin-like phosphoesterase superfamily.
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Ontology Term
PANTHER:PTHR23163 | RING FINGER PROTEIN-RELATED
 
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Ontology Term
Pfam:PF00561 | alpha/beta hydrolase fold
Description: This catalytic domain is found in a very wide range of enzymes.
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Ontology Term
PANTHER:PTHR10504 | BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED
 
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Ontology Term
PANTHER:PTHR22814:SF34 | COPPER TRANSPORT PROTEIN-RELATED
 
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Ontology Term
Pfam:PF07172 | Glycine rich protein family
Description: This family of proteins includes several glycine rich proteins as well as two nodulins 16 and 24. The family also contains proteins that are induced in response to various stresses.
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Ontology Term
PANTHER:PTHR12309 | SEC61 GAMMA SUBUNIT
 
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Ontology Term
PANTHER:PTHR22854 | TRYPTOPHAN BIOSYNTHESIS PROTEIN
 
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Ontology Term
PANTHER:PTHR22854:SF2 | INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE
 
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Ontology Term
Pfam:PF00218 | Indole-3-glycerol phosphate synthase
Description: NULL
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