Protein Domain : Bone marrow stromal antigen 2 IPR024886

Type  Family
Description  Bone marrow stromal antigen 2, also known as tetherin, is an antiretroviral defence protein, that blocks release of enveloped virus from the cell surface [ , , ]. Bst2/tetherin contains two membrane anchors which are employed to retain some enveloped viruses, including HIV-1, tethered to the plasma membrane in the absence of virus encoded antagonists []. Its expression is induced by interferon-alpha [] and was originally linked to B cell development [].
Short Name  BST2
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