Protein Domain : L-fucose isomerase, N-terminal-1 IPR012888

Type  Domain
Description  Proteins containing this domain are similar to L-fucose isomerase expressed by Escherichia coli ( , ). This enzyme corresponds to glucose-6-phosphate isomerase in glycolysis, and converts an aldo-hexose to a ketose to prepare it for aldol cleavage. The enzyme is a hexamer, with each subunit being wedge-shaped and composed of three domains. Both domains 1 and 2 contain central parallel β-sheets with surrounding alpha helices. Domain 1 demonstrates the beta-α-β-α-β Rossman fold. The active centre is shared between pairs of subunits related along the molecular three-fold axis, with domains 2 and 3 from one subunit providing most of the substrate-contacting residues, and domain 1 from the adjacent subunit contributing some other residues [ ].
Short Name  Fucose_iso_N1

0 Child Features

0 Gene Families

0 Genes

3 Ontology Annotations

0 Parent Features

0 Publications

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