Protein Domain : Transcription factor Maf family IPR024874

Type  Family
Description  Maf transcription factors form a distinct subfamily of the basic leucine zipper (bZip) transcription factors [ ]. Maf genes have been identified in a wide range of higher eukaryotes, including both vertebrate and invertebrate species. These proteins are unique among the bZip factors in that they contain a highly conserved extended homology region (EHR), or ancillary DNA binding region, in addition to a typical basic region, and both regions are involved in target DNA sequence recognition. Maf transcription factors regulate tissue-specific gene expression and cell-differentiation in a wide variety of tissues and are also involved in human diseases and oncogenic transformation. Tissue-specific expression invloves Maf binding to Maf-recognition elements (MAREs) in the regulatory regions of target genes, and interacting with other transcription factors.
Short Name  Transcription_factor_Maf_fam

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

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