v5.1.0.3
Glycine data from LIS
Type | Homologous_superfamily |
Description | This entry represents a domain superfamily found in the pretoxin HINT domain protein and the C-terminal of protein hedgehog.Hedgehog proteins are a family of secreted signal molecules required for embryonic cell differentiation. They are synthesised as inactive precursors with an N-terminal signalling domain linked to a C-terminal autoprocessing domain. The three-dimensional structure of the autoprocessing domain shows similarity with the β-strand core of intein splicing domains. It has hence been termed the Hedgehog/Intein (Hint) domain [ ]. |
Short Name | Hint_dom_sf |