Protein Domain : Translation initiation factor IF- 2 IPR015760

Type  Family
Description  Initiation factor 2 (IF-2) is one of the three factors required for the initiation of protein biosynthesis in bacteria [ ]. IF-2 promotes the GTP-dependent binding of the initiator tRNA to the small subunit of the ribosome. IF-2 is a protein of about 70 to 95kDa that contains a central GTP-binding domain flanked by a highly variable N-terminal domain and a more conserved C-terminal domain. Some members of this group undergo protein self splicing that involves a post-translational excision of the intein followed by peptide ligation. The function of IF-2 in facilitating the proper binding of initiator methionyl-tRNA to the ribosomal P site appears to be universally conserved [ ].
Short Name  TIF_IF2

2 Child Features

3 Gene Families

407 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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