Protein Domain : Dihydrofolate reductase-like domain superfamily IPR024072

Type  Homologous_superfamily
Description  Dihydrofolate reductase (DHFR) catalyses the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, an essential step in de novosynthesis both of glycine and of purines and deoxythymidine phosphate (the precursors of DNA synthesis) [ ], and important also in the conversion of deoxyuridine monophosphate to deoxythymidine monophosphate.This superfamily represents a structural domain found in dihydrofolate reductases, as well as in riboflavin biosynthesis proteins (usually as a C-terminal domain) and related enzymes.
Short Name  DHFR-like_dom_sf
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0 Child Features

3 Gene Families

Trail: ProteinDomain

419 Genes

Trail: ProteinDomain

0 Ontology Annotations

0 Parent Features

14 Publications

Trail: ProteinDomain
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