Protein Domain : Rad21/Rec8-like protein, C-terminal, eukaryotic IPR006909

Type  Domain
Description  This domain represents a conserved C-terminal region found in eukaryotic cohesins of the Rad21, Rec8 and Scc1 families. Rad21/Rec8 like proteins mediate sister chromatid cohesion during mitosis and meiosis, as part of the cohesin complex [ ]. Cohesion is necessary for homologous recombination (including double-strand break repair) and correct chromatid segregation. These proteins may also be involved in chromosome condensation. Dissociation at the metaphase to anaphase transition causes loss of cohesion and chromatid segregation [].
Short Name  Rad21/Rec8_C_eu
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0 Child Features

0 Gene Families

446 Genes

Trail: ProteinDomain

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13 Publications

Trail: ProteinDomain
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