Protein Domain : Regulatory factor, effector binding domain superfamily IPR011256

Type  Homologous_superfamily
Description  The effector domain is found in bacterial regulatory proteins, such as transcription factors. The effector domain consists of a duplication of a beta/alpha/beta(2) motif, where the antiparallel beta sheets form a barrel structure. Several proteins contain this domain, such as the multidrug-binding domain of the transcription factor BmrR, which transcriptionally regulates multidrug transporters as well as acting as a multidrug-binding protein [ ], the C-terminal domain of the Rob transcription factor, which belongs to the AraC/XylS protein family that regulate genes involved in resistace to antibiotics, organic solvents and heavy metals [], and the gyrase inhibitory protein GyrI (SbmC, TeeB), which is induced by DNA damaging agents to suppress cell proliferation by inhibiting bacterial gyrase activity [].
Short Name  Reg_factor_effector_dom_sf

0 Child Features

6 Gene Families

784 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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