Protein Domain : 5'-3' exoribonuclease type 2 IPR017151

Type  Family
Description  5'-3'-exoribonucleases are enzymes that degrade RNA by removing terminal nucleotides from the 5' end. Hydrolytic exoribonucleases, to which this entry belongs, produce nucleotide monosphosphates. An exosome and a 5'-3'-exoribonuclease are important in the degradation of very unstable transcripts [ ].This entry includes 5'-3'exoribonuclease type 2 (Xrn2, also known as Rat1), which occurs in animal, plant and fungal lineages. They act as post-transcriptional gene silencing (PTGS) suppressors [ ]. In Saccharomyces cerevisiae, Rat1 serves to terminate RNA polymerase II (RNAPII) molecules engaged in the production of uncapped RNA []. This entry also includes plant Xrn3 and Xrn4.
Short Name  Xrn2/3/4

0 Child Features

0 Gene Families

249 Genes

3 Ontology Annotations

1 Parent Features

13 Publications

USDA
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