v5.1.0.3
Glycine data from LIS
Type | Family |
Description | 5'-3'-exoribonucleases are enzymes that degrade RNA by removing terminal nucleotides from the 5' end. Hydrolytic exoribonucleases, to which this entry belongs, produce nucleotide monosphosphates. An exosome and a 5'-3'-exoribonuclease are important in the degradation of very unstable transcripts [ ].This entry includes 5'-3'exoribonuclease type 2 (Xrn2, also known as Rat1), which occurs in animal, plant and fungal lineages. They act as post-transcriptional gene silencing (PTGS) suppressors [ ]. In Saccharomyces cerevisiae, Rat1 serves to terminate RNA polymerase II (RNAPII) molecules engaged in the production of uncapped RNA []. This entry also includes plant Xrn3 and Xrn4. |
Short Name | Xrn2/3/4 |