Protein Domain : RED-like, N-terminal IPR012916

Type  Domain
Description  This domain contains sequences that are similar to the N-terminal region of Red protein ( ). This and related proteins contain a RED repeat which consists of a number of RE and RD sequence elements [ ]. The region in question has several conserved NLS sequences and a putative trimeric coiled-coil region [], suggesting that these proteins are expressed in the nucleus []. Protein RED (also known as IK) is found in the nucleus and is a component of the spliceosome []. It is also associated with the spindle pole where it co-localizes with and interacts with the spindle assembly checkpoint protein MAD1 during metaphase and anaphase. Depletion of RED shortens the mitotic cycle and MAD1 is incorrectly localized [].
Short Name  RED_N
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0 Child Features

1 Gene Families

Trail: ProteinDomain

116 Genes

Trail: ProteinDomain

0 Ontology Annotations

0 Parent Features

14 Publications

Trail: ProteinDomain
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