Protein Domain : Membrane associated eicosanoid/glutathione metabolism-like domain superfamily IPR023352

Type  Homologous_superfamily
Description  This domain is found in a widespread superfamily known as MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) [ ]. Included in this superfamily are:5-lipoxygenase activating protein (gene FLAP), which seems to be required for the activation of 5-lipoxygenase.Leukotriene C4 synthase ( ), which catalyses the production of LTC4 from LTA4. Microsomal glutathione S-transferase II ( ) (GST-II), which also produces LTC4 from LTA4. Prostaglandin E synthase, which catalyses the synthesis of PGE2 from PGH2 (produced by cyclooxygenase from arachidonic acid). The structure of this domain consists of four transmembrane helices [ ].
Short Name  MAPEG-like_dom_sf

0 Child Features

2 Gene Families

63 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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