Protein Domain : FMN-dependent alpha-hydroxy acid dehydrogenase, active site IPR008259

Type  Active_site
Description  A number of oxidoreductases that act on alpha-hydroxy acids and which are FMN-containing flavoproteins have been shown [ , , ] to be structurally related.The first step in the reaction mechanism of these enzymes is the abstraction of the proton from the α-carbon of the substrate producing a carbanion which can subsequently attach to the N5 atom of FMN. A conserved histidine has been shown [ ] to be involved in the removal of the proton. The region around this active site residue is highly conserved and contains an arginine residue which is involved in substrate binding.
Short Name  FMN_hydac_DH_AS

0 Child Features

0 Gene Families

325 Genes

1 Ontology Annotations

0 Parent Features

13 Publications

USDA
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