Ontology Term : Pfam:PF01080 Presenilin EMBL-EBI
Description  Mutations in presenilin-1 are a major cause of early onset Alzheimer's disease [1]. It has been found that presenilin-1 (Swiss:P49768) binds to beta-catenin in-vivo [3]. This family also contains SPE proteins from C.elegans.
Namespace  Family
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