GO Term : GO:0030122 AP-2 adaptor complex Gene Ontology

Description  A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
Namespace  cellular_component
Obsolete  false

2 Data Sets

Trail: GOTerm

1 Ontology

Trail: GOTerm

163 Ontology Annotations

Trail: GOTerm

41 Parents

Trail: GOTerm

44 Relations

Trail: GOTerm

2 Synonyms

Trail: GOTerm
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