Protein Domain : DEK, C-terminal IPR014876

Type  Domain
Description  DEK is a chromatin associated protein that is linked with cancers and autoimmune disease. This domain is found at the C-terminal of DEK and is of clinical importance since it can reverse the characteristic abnormal DNA-mutagen sensitivity in fibroblasts from ataxia-telangiectasia (A-T) patients [ , ]. The structure of this domain shows it to be homologous to the E2F/DP transcription factor family []. This domain is also found in chitin synthase proteins like , and in protein phosphatases such as .
Short Name  DEK_C

0 Child Features

5 Gene Families

855 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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