Protein Domain : Alpha-ketoglutarate-dependent dioxygenase AlkB-like IPR027450

Type  Domain
Description  AlkB is a DNA repair enzyme that removes methyl adducts and some larger alkylation lesions from endocyclic positions on purine and pyrimidine bases. It is a dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron [ , ]. The catalytic core of AlkB is homologous to other Fe-2OG dioxygenases [ ]. Two discrete global conformations have been observed for AlkB, differing in accessibility of a putative oxygen-diffusion tunnel [].
Short Name  AlkB-like

0 Child Features

10 Gene Families

1000 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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