v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | AlkB is a DNA repair enzyme that removes methyl adducts and some larger alkylation lesions from endocyclic positions on purine and pyrimidine bases. It is a dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron [ , ]. The catalytic core of AlkB is homologous to other Fe-2OG dioxygenases [ ]. Two discrete global conformations have been observed for AlkB, differing in accessibility of a putative oxygen-diffusion tunnel []. |
Short Name | AlkB-like |