Protein Domain : RQC domain IPR018982

Type  Domain
Description  This entry represents the RQC domain, which is a DNA-binding domain found only in RecQ family enzymes [ ]. RecQ family helicases can unwind G4 DNA, and play important roles at G-rich domains of the genome, including the telomeres, rDNA, and immunoglobulin switch regions. This domain has a helix-turn-helix structure and acts as a high affinity G4 DNA binding domain []. Binding of RecQ to Holliday junctions involves both the RQC and the HRDC domains.
Short Name  RQC_domain

0 Child Features

1 Gene Families

246 Genes

3 Ontology Annotations

0 Parent Features

14 Publications

USDA
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