v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | This entry represents the RQC domain, which is a DNA-binding domain found only in RecQ family enzymes [ ]. RecQ family helicases can unwind G4 DNA, and play important roles at G-rich domains of the genome, including the telomeres, rDNA, and immunoglobulin switch regions. This domain has a helix-turn-helix structure and acts as a high affinity G4 DNA binding domain []. Binding of RecQ to Holliday junctions involves both the RQC and the HRDC domains. |
Short Name | RQC_domain |