Protein Domain : TAFII-230 TBP-binding IPR009067

Type  Domain
Description  In eukaryotes, the general transcription factor TFIID helps to regulate transcription by RNA polymerase II from class II promoters. TFIID consists of TATA-box-binding proteins (TBP) and TBP-associated factors (TAFIIs), which together mediate both activation and inhibition of transcription. In Drosophila, the N-terminal region of TAFII-230 (the TFIID 230kDa subunit) binds directly to TBP, thereby inhibiting the binding of TBP to the TATA box. The N-terminal domain is comprised of three alpha helices and a beta hairpin, which forms the core that occupies the DNA-binding surface of TBP [].
Short Name  TAF_II_230-bd

0 Child Features

1 Gene Families

100 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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