Protein Domain : AAA ATPase, CDC48 family IPR005938

Type  Family
Description  This family includes yeast CDC48 (cell division control protein 48) and the human orthologue, transitional endoplasmic reticulum ATPase (valosin-containing protein) [ ]. It also includes CDC48 homologues from Archaea []. These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus. The archeal homologue of eukaryotic CDC48/p97 functions with the 20S proteasome by unfolding substrates and passing them on for degradation []. CDC48 consists of an N-terminal domain that binds two hexameric ATPase rings (D1 and D2) surrounding a central pore [].
Short Name  AAA_ATPase_CDC48
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0 Child Features

1 Gene Families

Trail: ProteinDomain

438 Genes

Trail: ProteinDomain

1 Ontology Annotations

Trail: ProteinDomain

0 Parent Features

14 Publications

Trail: ProteinDomain
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