LIS - Legume Information System
Information about legume traits for crop improvement
GlycineMine
v5.1.0.3
Glycine data from LIS
v5.1.0.3
Glycine data from LIS
| Type | Family |
| Description | 6-phosphogluconolactonases (6PGL) , which hydrolyses 6-phosphogluconolactone to 6-phosphogluconate is one of the enzymes in the pentose phosphate pathway. Two families of structurally dissimilar 6PGLs are known to exist: the Escherichia coli (strain K12) YbhE [ ] and the Pseudomonas aeruginosa DevB [ ] types. This entry contains bacterial 6-phosphogluconolactonases (6PGL) YbhE-type which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonizing enzyme carboxy-cis,cis-muconate cyclase and muconate cycloisomerase , which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures have been reported for the E. coli 6-phosphogluconolactonase and Neurospora crassa muconate cycloisomerase. Structures of proteins in this family have revealed a 7-bladed β-propeller fold [ ].The surface antigen Lp49 from Leptospira interrogans, the causative agent of leptospirosis, contains a C-terminal beta propellor domain that is also included in this entry. The structure of the Lp49 protein has been solved, and because it is an antigen is a potential drug target [ ]. |
| Short Name | Lactonase_7-beta_prop |
