Protein Domain : Long-chain fatty acyl-CoA thioesterase FcoT-like IPR022598

Type  Family
Description  Proteins in this family have a HotDog fold. This family was formerly known as DUF2662. The structure of FcoT from M. tuberculosis [ ] suggested a thioesterase function. Assays showed that this protein was a thioesterase with a preference for long chain fatty acyl groups []. The maximal Kcat was observed for palmitoyl-CoA, although longer and shorter molecules were also cleaved. In solution this protein forms a homo-hexameric complex.
Short Name  FcoT_ThioEstase
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