Protein Domain : Bacteriophage DNA replication protein Gp16.7 IPR009595

Type  Family
Description  The early-expressed gene 16.7 is conserved in bacteriophage phi-29 and related phages. It encodes a membrane protein, GP16.7, consisting of an N-terminal transmembrane domain and a C-terminal DNA-binding and dimerisation domain. GP16.7 plays an important role in organising membrane-associated bacteriophage DNA replication [ , ]. The C-terminal domain has a similar secondary structure similar to homeodomains, but forms a fundamentally different tertiary structure consisting of a six-helical dimeric fold [ ]. Multimerisation of this dimer leads to efficient DNA binding.
Short Name  Phage_DNA_replic_GP16.7
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