GO Term : GO:0016236 macroautophagy Gene Ontology

Description  The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
Namespace  biological_process
Obsolete  false

1 Data Sets

Trail: GOTerm

1 Ontology

Trail: GOTerm

2 Ontology Annotations

Trail: GOTerm

9 Parents

Trail: GOTerm

83 Relations

Trail: GOTerm

2 Synonyms

Trail: GOTerm
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