v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | In animals, SETD1A/B are histone methyltransferases that produce mono-, di-, and trimethylated histone H3 at 'Lys-4. However, if 'Lys-9' residue is already methylated, 'Lys-4' will not be. The 'Lys-4' methylation is a tag for epigenetic transcriptional activation [ , ]. The animal COMPASS complex is composed of at least the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30 []. ATXR7, the Arabidopsis homologue to Set1, is required for the expression of the flowering repressors FLC and MADS-box genes of the MAF family [, ]. ATXR7 is also involved in the control of seed dormancy and germination [].This entry represents the SET domain found in SETD1A/B and its homologues. |
Short Name | SET_SETD1A/B |