Protein Domain : U2A'/phosphoprotein 32 family A, C-terminal IPR003603

Type  Domain
Description  This motif occurs C-terminal to leucine-rich repeats in "sds22-like"and "typical"LRR-containing proteins. Examples from the metazoa are described as either "Acidic leucine-rich nuclear phosphoprotein 32 family member A"or have been characterised as U2A', the protein that interacts with U2B'' facilitating the interaction with U2 snRNA. U2A' is required for the spliceosome assembly and the efficient addition of U2 snRNP onto the pre-mRNA [ ]. The crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA has been described [ ].
Short Name  U2A'_phosphoprotein32A_C

0 Child Features

2 Gene Families

160 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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