Protein Domain : Autophagy protein Atg8 ubiquitin-like IPR004241

Type  Family
Description  A number of autophagy-related proteins have been identified in yeast, including the key autophagic protein Atg8, which is a ubiquitin-like protein with a structure consisting of two amino-terminal α-helices and a ubiquitin-like core [ , ]. Many other eukaryotes contain multiple Atg8 orthologues. Atg8 genes of multicellular animals can be divided into three subfamilies: microtubule-associated protein 1 light chain 3 (MAP1LC3 or LC3) [], gamma-aminobutyric acid receptor-associated protein (GABARAP) and Golgi-associated ATPase enhancer of 16kDa (GATE-16) [, ]. Family members are involved in diverse intracellular trafficking and autophagy processes.
Short Name  Atg8-like

1 Child Features

4 Gene Families

717 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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