Protein Domain : DNA polymerase I-like, H3TH domain IPR020045

Type  Domain
Description  This entry represents the H3TH (helix-3-turn-helix) domain of the 5'-3' exonuclease (53EXO) of mutli-domain DNA polymerase I and single domain protein homologues. Taq (Thermus aquaticus) DNA polymerase I contains a polymerase domain for synthesizing a new DNA strand and a 53EXO domain for cleaving RNA primers or damaged DNA strands [ , ]. Taq's 53EXO recognizes and endonucleolytically cleaves a structure-specific DNA substrate that has a bifurcated downstream duplex and an upstream template-primer duplex that overlaps the downstream duplex by 1 bp [].
Short Name  DNA_polI_H3TH
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0 Child Features

0 Gene Families

727 Genes

Trail: ProteinDomain

2 Ontology Annotations

Trail: ProteinDomain

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13 Publications

Trail: ProteinDomain
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