Protein Domain : Histone acetyltransferase type B, catalytic subunit IPR017380

Type  Family
Description  This entry represents the catalytic subunit of histone acetyltransferase type B ( ) (also known as HAT1), which is the catalytic component of the histone acetylase B (HAT-B) complex [ , , ]. The HAT-B complex is composed of at least HAT1 and HAT2. In the cytoplasm, this complex binds to the histone H4 tail. In the nucleus, the HAT-B complex has an additional component, the histone H3/H4 chaperone HIF1.This enzyme acetylates soluble but not nucleosomal H4 at Lys-12, which is required for telomeric silencing. HAT1 has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. It is involved in DNA double-strand break repair [ ].
Short Name  Hist_AcTrfase_B-typ_cat-su

0 Child Features

1 Gene Families

103 Genes

4 Ontology Annotations

0 Parent Features

14 Publications

USDA
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