Protein Domain : GMP synthase, glutamine amidotransferase IPR004739

Type  Domain
Description  This signature represents the type 1 glutamine amidotransferase (GATase1) domain found in the N-terminal region of GMP synthase . GMP synthase catalyzes the synthesis of GMP from XMP [ ], [].ATP + xanthosine 5'-phosphate + L-glutamine + H(2)O = AMP + diphosphate + GMP + L-glutamate GMP synthetase is a glutamine amidotransferase from the de novo purine biosynthetic pathway. It belongs to the triad family of amidotransferases having a conserved Cys-His-Glu catalytic triad in the glutaminase active site [ ].Glutamine amidotransferase (GATase) activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate.
Short Name  GMP_synth_GATase

0 Child Features

1 Gene Families

103 Genes

3 Ontology Annotations

1 Parent Features

14 Publications

USDA
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