Protein Domain : Methyltransferase HemK-like IPR004556

Type  Family
Description  This entry includes HemK (also known as PrmC) from Escherichia coli. HemK methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif [ , ]. Its homologue in Saccharomyces cerevisiae, Mtq1, is a methyltransferase that methylates MRF1 on 'Gln-287' using S-adenosyl L-methionine as methyl donor []. Homologues are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both Escherichia coli and Haemophilus influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain.
Short Name  HemK-like

3 Child Features

0 Gene Families

101 Genes

2 Ontology Annotations

0 Parent Features

13 Publications

USDA
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