Protein Domain : Inosine-5'-monophosphate dehydrogenase IPR005990

Type  Family
Description  This entry includes inosine-5'-monophosphate dehydrogenases and guanosine 5'-monophosphate (GMP) reductase. Inosine-5'-monophosphate dehydrogenase catalyses the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth [ , ]. GMP catalyses the irreversible NADPH-dependent deamination of GMP to IMP [].
Short Name  IMP_DH

2 Child Features

1 Gene Families

116 Genes

2 Ontology Annotations

0 Parent Features

14 Publications

USDA
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