Protein Domain : YbaK/aminoacyl-tRNA synthetase-associated domain IPR007214

Type  Domain
Description  Bacterial prolyl-tRNA synthetases and some smaller paralogues, YbaK and ProX, can hydrolyse misacylated Cys-tRNA(Pro) or Ala-tRNA(Pro) [ ]. The small bacterial protein Ybak preferentially hydrolyses Cys-tRNA(Pro) and Cys-tRNA(Cys) [, ]. ProX functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro) []. Prolyl-tRNA synthetases main function is to catalyse the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro) [].This entry represents a domain characteristic of Ybak and ProX, that can also be found with other domains in prolyl-tRNA synthetases.
Short Name  YbaK/aa-tRNA-synth-assoc-dom
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0 Child Features

2 Gene Families

Trail: ProteinDomain

258 Genes

Trail: ProteinDomain

1 Ontology Annotations

Trail: ProteinDomain

0 Parent Features

14 Publications

Trail: ProteinDomain
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