LIS - Legume Information System
Information about legume traits for crop improvement
GlycineMine
v5.1.0.3
Glycine data from LIS
v5.1.0.3
Glycine data from LIS
| Type | Domain |
| Description | SUMT, an enzyme of the cobalamin and siroheme biosynthetic pathway, catalyses the transformation of uroporphyrinogen III into precorrin-2. It transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. SUMT is the first enzyme committed to the biosynthesis of siroheme or cobalamin (vitamin B12), and precorrin-2 is a common intermediate in the biosynthesis of corrinoids such as vitamin B12, siroheme and coenzyme F430 [, ]. In some organisms, the SUMT domain is fused to the precorrin-2 oxidase/ferrochelatase domain to form siroheme synthase or to uroporphyrinogen-III synthase to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase. |
| Short Name | CobA/CysG_C |
